Clinical trials: In-Hospital Cardiac Arrest
Cardiovascular Risk Factors, Coronary Disease
CPR Training: Video Self-Instruction Kit or Video-Only
Prompt delivery of cardiopulmonary resuscitation (CPR) is a crucial determinant of survival for many victims of sudden cardiac arrest (SCA), yet bystander CPR is provided in less than one third of witnessed SCA events.
- Conditions
- Cardiovascular Risk Factors, Coronary Disease, Cardiac Arrest
- Trial name
- NCT01514656
- Testing
- CPR Training using the Family and Friends CPR Anytime Video Self Instruction, Implementation of a Hospital-based CPR Training Model, Follow-up prompting to encourage skill retention
- Where
- 3 sites in United States
- Volunteers
- 1,870 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Out-of-Hospital Cardiac Arrest
AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
The investigators aimed to evaluate the effect of AMCPR (Augmented-Medication CardioPulmonary Resuscitation: administration of additional vasopressin to titrate to arterial diastolic blood pressure over 20 mmHg) on…
- Trial name
- NCT03191240
- Testing
- Vasopressins, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- Asan Medical Center
Out-Of-Hospital Cardiac Arrest
Sex-unique Disparities in Survival and Resuscitation After Out-of-hospital Cardiac Arrest - a Danish Analysis
The goal of this observational study is to investigate characteristics in out-of-hospital cardiac arrests (OHCA) related to sex differences.
- Trial name
- NCT05583084
- Testing
- Investigation
- Volunteers
- 27,000 people
- Sponsor
- Prehospital Center, Region Zealand
Shockable Out of Hospital Cardiac Arrest
CYclosporine A in Shockable Out-of-hospital Cardiac Arrest ResUScitation
Cardiac arrest (CA) is a public health problem in industrialized countries. The prognosis of these patients remains poor with significant mortality and severe neurological sequelae in survivors.
- Trial name
- CYRUS II (NCT02887807)
- Testing
- Single intravenous bolus of cyclosporine A (2.5 mg/kg) at the onset of resuscitation
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Education, Medical, Undergraduate, Out-of-Hospital Cardiac Arrest
Serious Game Versus Online Course to Pre-train Medical Students on the Management of an Adult Cardiac Arrest.
The objective of this study is to compare two forms of pre-training (an online narrative presentation and a serious game) to prepare 2nd year medical students for a hands-on training with physical simulators about out-of-hospital…
- Conditions
- Education, Medical, Undergraduate, Out-of-Hospital Cardiac Arrest, Simulation Training
- Trial name
- NCT02758119
- Testing
- Serious Game, Online course
- Where
- France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ilumens
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Outcome From Traumatic Cardiac Arrest
This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest.
- Trial name
- NCT05294575
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Cardio Respiratory Arrest
Effectiveness of a Network of Trained Volunteers Automatically Activated, on the Reduction of the Start Time of Cardiopulmonary Resuscitation Maneuvers. Study Protocol.
Background Cardiorespiratory arrest (CRA) is a health emergency with high mortality. Mortality could depends on the start time of cardiopulmonary resuscitation (CPR) maneuvers (and the quality of its performance) and the use of…
- Trial name
- Smartwatch (NCT03828305)
- Testing
- Training and creation of the Network-CPR, Control Group
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Sudden Cardiac Death, Arrhythmia
Selection of Shock Energy in Out-Of-Hospital Cardiac Arrest
Sudden cardiac death is the most frequent cause of death in industrialized countries. The most efficient interventiont in ventricular fibrillation is defibrillation in an appropriate timely manner.
- Conditions
- Sudden Cardiac Death, Arrhythmia, Survival
- Trial name
- NCT00472147
- Testing
- shock efficacy
- Where
- Germany
- Sponsor
- Charite University, Berlin, Germany
Cardiac Arrest, Morality
Call to Door Timing in Out-of-hospital Cardiac Arrest
The investigators aimed to investigate the effect of delayed hospitalization on the basis of the call time on the clinical outcomes of patients with OHCA patients using a nationwide OHCA registry.
- Trial name
- NCT05724914
- Where
- South Korea
- Volunteers
- 182,508 people
- Sponsor
- Yonsei University
Cardiac Arrest
Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Out of Hospital Cardiac Arrest
Even in patients with successful return of spontaneous circulation (ROSC), outcome after cardiac arrest remains poor. The overall in-hospital survival rate widely varies both worldwide and across communities, from 1 to 4 folds…
- Trial name
- AfterROSC1 (NCT04167891)
- Testing
- Calculation of early prognosis score
- Where
- 27 sites in Belgium, France
- Volunteers
- 1,144 people
- Sponsor
- AfterROSC
Cardiac Arrest With Successful Resuscitation, Cardiac Arrest, Cause Unspecified
Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian Region
This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.
- Trial name
- NCT07009652
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Cardiovascular Risk Factors, Coronary Disease
Cardiopulmonary Resuscitation (CPR) Dissemination Study Using Nurses and Volunteers
Each year in the United States, 300,000 people suffer from Cardiac Arrest (CA), and of them there is a 90% mortality rate. Out-of-Hospital arrests in particular have a 1-5% survival to hospital discharge.
- Conditions
- Cardiovascular Risk Factors, Coronary Disease, Cardiac Arrest
- Trial name
- NCT01252316
- Testing
- CPR Training using the Family and Friends CPR Anytime VSI Kit, Implementation of an In-Hospital CPR Training Model
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Out-of-Hospital Cardiac Arrest
Induced Hypothermia in Cardiac Arrest Patients Rescued by Extracorporeal Cardiopulmonary Resuscitation.
Background： Cardiopulmonary resuscitation (CPR) with closed-chest cardiac massage has been shown that survival to discharge rate is poor.
- Trial name
- NCT00965016
- Testing
- hypothermia
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Min-Sheng General Hospital
Cardiac Arrest, Out-Of-Hospital, Ventricular Fibrillation
Ventricular Fibrillation Following Out-of-hospital Cardiac Arrest
The majority of survivors suffering an out-of-hospital cardiac arrest (OHCA) are those who initially present with a shockable rhythm, which is usually ventricular fibrillation (VF).
- Trial name
- NCT05325385
- Testing
- There are no interventions - this is a database study only
- Where
- United Kingdom
- Volunteers
- 15,000 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Cardiac Arrest, Sudden, Cardiopulmonary Arrest
The Success Rate of Cardiopulmonary Resuscitation in Patients Experiencing In-hospital Cardiac Arrest
Cardiac arrest causes the heart to stop functioning to maintain circulation that provides oxygen to the brain. The global incidence of cardiac arrest is 50 to 60 per 100,000 people per year.
- Conditions
- Cardiac Arrest, Sudden, Cardiopulmonary Arrest, Cardiopulmonary Failure, In-hospital Cardiac Arrest
- Trial name
- NCT04786860
- Testing
- CPR
- Where
- 2 sites in Indonesia
- Volunteers
- 415 people
- Sponsor
- Udayana University
Cardio-respiratory Arrest, Prolactin
Evaluating Prognostic Contribution of Lactate on Recovery of Spontaneous Cardiac Activity After Cardiac Arrest
Incidence of non-hospital cardio-respiratory arrest (ACR) in France is around 40 000 cases per year, with mortality remaining very high, with 75% of patients dying before arrival in hospital.
- Trial name
- PROLAC (NCT03325452)
- Testing
- venous lactate
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Out-Of-Hospital Cardiac Arrest, Foreign Body Aspiration
Foreign Body Airway Obstruction, Incidence, Survival EMS-treatment and First Aid Treatment by Laypersons
Background: Foreign body airway obstruction (FBAO) is often described as an uncommon cause of Out of Hospital Cardiac Arrest (OHCA) accounting for approximately 1.4% of all OHCA.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Foreign Body Aspiration, Cardiopulmonary Arrest
- Trial name
- NCT04279860
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Out-of-hospital Cardiac Arrest (OHCA)
Application of Transesophageal Echocardiography in Pre-hospital Cardiac Arrest Patients
The Use of Point-of-Care Ultrasound (POCUS), Transthoracic Echocardiography (TTE), and Transesophageal Echocardiography (TEE) in Cardiac Arrest and Acute Coronary Syndrome Patients Studies have shown that POCUS can rapidly change…
- Trial name
- TAPCAP (NCT06672315)
- Testing
- transesophageal echocardiography
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Jen-Tang Sun
Out-Of-Hospital Cardiac Arrest
The Impact of Aortic Valve Compression During Cardio-pulmonary Resuscitation on Patients With Out-of-hospital Cardiac Arrest
Purpose: This study aims to find out if the current way of performing chest compressions during resuscitation for patients who have suffered a cardiac arrest outside of the hospital is affecting their chances of recovery.
- Trial name
- AVC in OHCA (NCT05932784)
- Testing
- transesophageal echocardiography
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiac Arrest
The Assessment of Survival After In-hospital Cardiac Arrest for 2 Years in Tertiary Hospital
Define the frequency and survival pattern of cardiac arrests in relation to the hospital day of event and etiology of arrest.
- Trial name
- IHCA (NCT03484559)
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Aydin Adnan Menderes University