Clinical trials: In-Vitro Fertilization
Infertility, Female
Study to Compare Efficacy and Safety of Primapur and Gonal-f in Women for Assisted Reproductive Treatment
The purpose of this study is to show equivalence with regard to the number of oocytes retrieved between follitropin alfa (pen-injectors) Primapur® and Gonal-f® in woman undergoing IVF/ICSI
- Trial name
- NCT03088137
- Testing
- Follitropin alfa (Gonal-f), Follitropin alfa (Primapur)
- Where
- 3 sites in Russia
- Volunteers
- 118 people
- Sponsor
- IVFarma LLC
Infertility, In-vitro Fertilization
NuvaRing vs. Oral Contraceptive Pills (OCP) for In-Vitro Fertilization (IVF) Pre-treatment
The newly designed contraceptive ring, Nuvaring has a lower total steroid dose, and medications are delivered locally. It has been proven to be as safe and effective as the combined OCP in ovarian suppression and preventing…
- Trial name
- NCT01298128
- Testing
- NuvaRing, marvelon
- Volunteers
- 70 people
- Sponsor
- University of Toronto
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility
Low Dose hCG in the Late Follicular Phase
In this study,the investigators compared two protocols for controlled ovarian hyperstimulation in infertility patients requiring IVF. In the control group, the patient undergoes a standard antagonist protocol.
- Trial name
- NCT00750100
- Testing
- human chorionic gonadotropin, recombinant gonadotropins
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Transabdominal US-guided (UGET) vs. Modified Transvaginal US-guided (mTVET) Embryo Transfer in Human IVF
One thousand, six hundred forty-eight IVF patients undergoing ET with fresh embryos, randomized to receive mTVET (n=828) or UGET (n=820).
- Trial name
- NCT02526472
- Testing
- ET under transabdominal US guidance (UGET), ET after transvaginal US uterine measurement (mTVET)
- Where
- Italy
- Volunteers
- 1,648 people
- Sponsor
- University of Turin, Italy
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin Antagonist on Reduction of Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban compared to placebo on uterine contractions on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- EFFORT (NCT01043120)
- Testing
- Barusiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Autoimmune Diseases
Research of Predictive Factors of in Vitro Fertilization (IVF) Outcome AI-IVF Study
Infertility is the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected intercourse, while subfertility means a delay in achieving pregnancy.
- Trial name
- AI-IVF (NCT06872294)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Infertility
What Embryoselection for What Chance of Success ? EmbryoSelect Study
The aim of the research is to evaluate the results of the first in vitro fertilization (IVF) attempt according to the type of embryo culture.
- Trial name
- EmbryoSelect (NCT04484181)
- Testing
- Embryo culture in time lapse technology (TLT), Embryo culture in conventional incubator
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
IVF
Pivotal Observational CHLOE Study
This pivotal study is an observational, prospective assessment, multi-center, databank based, clinical study aimed to evaluate the performance of CHLOE™ algorithm in prediction of blastocyst formation.
- Trial name
- NCT06111365
- Testing
- CHLOE
- Where
- 3 sites in United States
- Volunteers
- 59 people
- Sponsor
- Fairtility
GDM, Insulin Resistance
In Vitro Fertilization Impact on Metabolic Parameters
A quantitative prospective cohort study will be conducted, where blood samples will be collected at different timings during the IVF protocol, to assess the impact of fertility medications on metabolic parameters of patients…
- Conditions
- GDM, Insulin Resistance, Glucose Intolerance, PCOS
- Trial name
- IVF (NCT03426228)
- Testing
- HbA1C
- Where
- United Arab Emirates
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Salidroside, Randomized Controlled Trial
Effect of Salidroside on Pregnancy Outcomes in High Childbearing Age Patients in Viro Fertilization
With the decreasing of birth rate and population in our country, population problem has become a long-term and strategic problem.
- Conditions
- Salidroside, Randomized Controlled Trial, In Vitro Fertilization, Assisted Reproductive Technology
- Trial name
- NCT06990685
- Testing
- Salidroside
- Where
- China
- Volunteers
- 370 people
- Sponsor
- The Second Hospital of Shandong University
Acupuncture, in Vitro Fertilization
The Differences of Oocyte Maturation, Granulosa Cell Apoptosis Index Between Electroacupuncture And Sham Groups IVF
Interventional studies compared electroacupuncture group versus sham electroacupuncture group to granulosa cell apoptosis index, oocyte maturation, GDF9 and BMP15 levels, and fertilization rate in in vitro fertilization program
- Conditions
- Acupuncture, in Vitro Fertilization, BCL2 Gene mRNA Overexpression, Oocyte Maturation
- Trial name
- NCT03627533
- Testing
- Electroacupuncture
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
in Vitro Fertilization
Follicular Fluid Sialic Acid Levels in IVF Cycles
This cross-sectional study was conducted at the Reproductive Endocrinology and Invitro Fertilization (REI) unit of our hospital, following the approval of the hospital's ethics committee.
- Trial name
- NCT03745027
- Testing
- in vitro fertilization
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Polycystic Ovary Syndrome, Infertility
Live Birth After Fresh Embryo Transfer Vs Frozen-thawed Embryo Transfer in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of childbearing age. However, the optimal infertility treatment for PCOS patients is still a matter of controversy.
- Trial name
- FreFro-PCOS (NCT01841528)
- Testing
- fresh embryo transfer, frozen-thawed embryo transfer
- Where
- 14 sites in China
- Volunteers
- 1,180 people
- Sponsor
- Zi-jiang Chen
Cancer
In Vitro Fertilization and Pregnancy After Use of Chemotherapy
Objective: Chemotherapy regimens containing alkylating agents result in primordial follicle death and premature ovarian failure. Depending on the age and the type/dose of chemotherapy, some women may continue to menstruate.
- Trial name
- NCT00520364
- Testing
- Observation of IVF outcomes in relation to chemo history and AMH
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- New York Medical College
In Vitro Fertilization
Prediction of Ovarian Response
The purpose of this study is to evaluate if there is an association between the endocrine and ultrasonographic markers of ovarian reserve and the IVF outcome and to determine which markers contribute to the prediction of poor…
- Trial name
- NCT00557687
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Mood Disorders
Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes
The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment.
- Trial name
- IVF (NCT01032421)
- Testing
- IVF procedure
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Embryo Transfer, Fertilization in Vitro
Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?
The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates.
- Conditions
- Embryo Transfer, Fertilization in Vitro, Coitus
- Trial name
- NCT06134609
- Testing
- Sexual intercourse
- Where
- Israel
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility
Luteal Phase FSH in the IVF Poor Responder
In vitro fertilization (IVF) is a common procedure used to assist couples who have difficulty conceiving a pregnancy. IVF is a process where oocytes (eggs) are retrieved from a woman's ovaries and fertilized with sperm in the…
- Trial name
- NCT00225433
- Testing
- follitropin beta, ganirelix acetate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania