Clinical trials: In-Vitro Fertilization
Infertility
Protocols for Improved in Vitro Fertilization (IVF) Outcomes
Many infertile patients have a decreased chance of becoming pregnant when using in vitro fertilization (IVF). For these patients, many different treatments are available, but none of them have been shown to be better than the…
- Trial name
- NCT00334243
- Testing
- Microflare protocol for IVF, Antagonist protocol for IVF, Demi-halt protocol for IVF
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
In Vitro Fertilization
Initial Experience of Transabdominal Fetal Reduction in Nepal
Multifetal pregnancies are common in in vitro fertilization. Multifetal gestation increases maternal and fetal morbidity and mortality. We perform fetal reduction in our hospital by intra-thoracic injection of potassium chloride.
- Trial name
- NCT06251440
- Testing
- Fetal Reduction
- Where
- Nepal
- Volunteers
- 108 people
- Sponsor
- Grande International Hospital, Nepal
IVF Outcome
Trigger Timing in Ovarian Stimulations
The gonadotrophin-releasing hormone (GnRH) antagonist protocol is widely used in in vitro fertilisation (IVF) for its flexibility and ability to reduce the risk of ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT04163133
- Testing
- 1-2 days later trigger than regular timing
- Where
- China
- Volunteers
- 834 people
- Sponsor
- Peking University Third Hospital
Infertility, Infertility, Female
Follicular Fluid Fetuins in in Vitro Fertilization
This study aims to investigate whether follicular fluid concentrations of fetuin A and fetuin B are associated with the clinical pregnancy and live birth rates in in vitro fertilization (IVF) cycles.Twenty-nine women with poor…
- Trial name
- NCT04201847
- Testing
- Serum test
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Samsun Education and Research Hospital
Infertility
The Effectiveness of Endometrial Injury in IVF
Many studies have demonstrated that endometrial scratch significantly increase pregnancy rate in patients undergoing in vitro fertilization and embryo transfer.
- Trial name
- NCT02409745
- Testing
- endometrial scratch
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Pregnancy, Neonates
Pregnancy & Neonatal Follow-up of Ongoing Pregnancies Established During Clinical Trial 38826 (Study 38827)(P06056)(COMPLETED)
The objective of this trial was to evaluate whether Org 36286 treatment for the induction of multifollicular growth in women undergoing controlled ovarian stimulation (COS) for in vitro fertilization (IVF) or intracytoplasmatic…
- Trial name
- NCT00702988
- Testing
- Org 36286, recFSH
- Volunteers
- 44 people
- Sponsor
- Organon and Co
Women Infertility
Myo-inositol/D-chiro-inositol Ratio in Follicular Fluid
Considering the importance assumed by follicular microenvironment for a proper oocyte development, this study is a prospective observational clinical trial which aims to evaluate whether the embryo blastocyst quality may be…
- Trial name
- NCT03055442
- Testing
- Dosage of myo-inositol, Dosage of D-chiro-inositol
- Where
- Greece
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
In Vitro Fertilization, Controlled Ovarian Stimulation
N680S Polymorphism of the FSHR Gene and Its Relationship With the Type of Gonadotropin Used in COS
This project wants to determinate whether there is a relationship between the N680S polymorphism genotype of the FSHR gene and the nature of the FSH used in controlled ovarian stimulation.
- Trial name
- NCT04122729
- Where
- 12 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Angelini Farmacéutica
Infertility
Dehydroepiandrosterone (DHEA)Supplementation Pre-IVF(In Vitro Fertilization) Cycles
The purpose of this study is to compare the effect of pre-IVF cycles treatment with and without DHEA(Dehydroepiandrosterone) on the ovarian reserve markers, the number of oocytes obtained and IVF(in vitro fertilization) outcomes…
- Trial name
- IVF (NCT02866253)
- Testing
- DHEA
- Volunteers
- 78 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility
Endometrial Injury and in Vitro Fertilization Outcomes
Infertility affects 1 in 7 couples worldwide. The most successful treatment is in vitro fertilization (IVF), a procedure where a woman's eggs are collected and fertilized with sperm to make embryos, which are then placed in the…
- Trial name
- NCT02153814
- Testing
- Endometrial Scratch
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Northwestern University
Subfertility
Prognostic Value of Progesterone for In Vitro Fertilization (IVF) Outcome
This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF…
- Trial name
- PROG2 (NCT01067664)
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Aristotle University Of Thessaloniki
Female Infertility
Use of IMSI in Poor Responders to IVF
This is a pilot study which aims to determine the role of IMSI in poor responders.
- Trial name
- NCT02358733
- Testing
- Intra-cytoplasmic Sperm Injection, Intra-cytoplasmic Morphologically-selected Sperm Injection
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Centro de Infertilidad y Reproducción Humana
Subfertility
Use of Atosiban in in Vitro Fertilization (IVF) Treatment
The hypothesis of this randomized double blind study is that the live birth rates are significantly higher after the use of atosiban prior to the embryo transfer in patients undergoing in vitro fertilization (IVF) treatment.
- Trial name
- NCT01501214
- Testing
- Atosiban, Normal saline
- Where
- 2 sites in China, Vietnam
- Volunteers
- 800 people
- Sponsor
- The University of Hong Kong
Infertility
Split Cohort Trial Comparing IVF Outcomes After the Use of Testicular vs. Ejaculated Sperm for ICSI
The primary objective of this study is to determine if there is a difference in in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) outcomes when using testicular sperm versus ejaculated sperm in couples…
- Trial name
- NCT03483298
- Testing
- ICSI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
The Impact of Lifestyle Behavior on in Vitro Fertilization (IVF) Outcome
The purpose of this study is to prospectively examine the impact of various lifestyle habits in both men and women on the outcome of in vitro fertilization.
- Trial name
- NCT01404858
- Testing
- There is no intervention; this is a survey only study
- Where
- United States
- Volunteers
- 12,800 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility
Needle-Free Monitoring for IVF Patient Cycles
Salivary diagnostic testing is emerging as a less invasive, inexpensive alternative to serum analyte measurements with proven diagnostic accuracy in clinical settings.
- Trial name
- NCT03162809
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston IVF
IVF
Evaluate the Effectiveness of Progestin-Primed Versus GnRH Antagonist Protocols in Vietnamese Women Undergoing In-vitro Fertilization
This study aims to evaluate the efficacy of the progestin-primed ovary stimulation (PPOS) protocol compared to the standard GnRH antagonist (GnRH_ant) protocol across successive stages in a controlled ovarian stimulation (COS)…
- Trial name
- NCT06191809
- Testing
- Controlled Ovarian Stimulation Protocol
- Where
- Vietnam
- Volunteers
- 200 people
- Sponsor
- Hanoi Medical University
Infertility, Female
Evaluation of Different Culture Media for in Vitro Fertilization
Under in vivo conditions, human gametes and embryos are exposed to fluids in the fallopian tubes, where fertilization occurs, and in the uterus, the site of embryonic implantation.
- Trial name
- NCT05676515
- Testing
- culture media
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diminished Ovarian Reserve, IVF
Study of G-CSF for DOR in Patients Undergoing IVF
Diminished ovarian reserve (DOR) is defined by reduced follicle counts in women, associated with decreased fertility and lower success rates with In Vitro Fertilization (IVF).
- Conditions
- Diminished Ovarian Reserve, IVF, G-CSF, Granulocyte Colony Stimulating Factor
- Trial name
- NCT07871825
- Testing
- Neupogen 300 μg subcutaneous injection, Subcutaneous injections of a saline solution
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Center for Human Reproduction
Acupuncture, Quality of Life
Acupuncture as a Complementary Therapy for in Vitro Fertilization Patients: a Randomized Controlled Trial
This is an open-label randomized controlled trial of the use of acupuncture in infertile patients receiving In Vitro Fertilization (IVF).
- Conditions
- Acupuncture, Quality of Life, Infertility, Stress
- Trial name
- NCT03142490
- Testing
- Acupuncture, Questionnaires
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Minas Gerais