Clinical trials: In-hospital Mortality
Critical Illness, Malnutrition
Association Between Malnutrition and Clinical Outcomes in the Intensive Care Unit
Previous studies have demonstrated the direct associations between malnutrition and hospital mortality as well as the length of stay in critically ill patients.
- Trial name
- NCT03213899
- Volunteers
- 503 people
- Sponsor
- JurongHealth
Post-craniotomy, Critical Illness
Scores in Critically Ill Patients After Craniotomy
This study planned to review patients admitted to three ICU wards at Beijing Tiantan Hospital between 2017 and 2020. It focused on adult patients who had undergone craniotomy and stayed in the ICU for more than 24 hours.
- Conditions
- Post-craniotomy, Critical Illness, Mortality, Severity of Illness Scores
- Trial name
- SCORES (NCT06762184)
- Where
- Chile
- Volunteers
- 1,600 people
- Sponsor
- Beijing Tiantan Hospital
Measles Vaccination, Oral Polio Vaccine
Vaccine Campaign Effects on General Hospital Admissions and Mortality Among Children
The world is set on eradicating measles and polio infections in the coming decade. Once both infections are under control, campaigns with measles and oral polio vaccines will be phased out.
- Conditions
- Measles Vaccination, Oral Polio Vaccine, Non-specific/Heterologous Effects of Vaccines, Mortality
- Trial name
- RE-CAMP (NCT03460002)
- Testing
- Measles vaccine, Oral polio vaccine
- Where
- Guinea-Bissau
- Volunteers
- 28,612 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
All-cause Mortality
ADL and CONUT for Predicting 1-year Mortality Risk in Older Adults After Hip Fracture
Hip fracture has a serious impact on the quality of life and even the survival of older adults. The multidisciplinary management of hip fracture has been shown to be effective in improving patient outcome and cost-effective in…
- Trial name
- NCT05814172
- Testing
- no intervention
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Beijing Tongren Hospital
Cholecystolithiasis, Cholecystitis
Influence of Hospital Volume on Mortality and Short-term Postoperative Outcomes in Uncomplex General Surgery in Switzerland
The effect of centralisation measures on the operative outcomes after any type of surgery in Switzerland has not been highlighted yet.
- Conditions
- Cholecystolithiasis, Cholecystitis, Inguinal Hernia, Femoral Hernia
- Trial name
- NCT07022665
- Testing
- Appendicectomy, Cholecystectomy, Umbilical hernia repair
- Where
- Switzerland
- Volunteers
- 399,701 people
- Sponsor
- Cantonal Hospital of St. Gallen
Femur Fracture, Morality
Mortality of Patients Undergoing Fracture of the Upper Extremity u Femur at the University Hospital of Amiens
Fractures of the upper femur (EFSF) represent a major public health problem in the elderly. Approximately 1.6 million patients are victims each year of an EFSF and this number is increasing as a result of the aging of the…
- Trial name
- FESF-Amiens (NCT03117868)
- Testing
- Study of mortality at 6 months
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Head Trauma
Early Induced Hypernatremia for the Prevention and Management of Brain Edema
The purpose of this study is to estimate the effect of an early induced hypernatremia protocol (150-155 milliequivalent/L) versus normonatremia plus mannitol (135 - 145 milliequivalent/L) in terms of neurologic outcome in…
- Trial name
- EHIBE (NCT02798601)
- Testing
- Hypernatremia
- Sponsor
- Hospital Pablo Tobón Uribe
Cholecystitis
Harmonic in Laparoscopic Cholecystectomy for Acute Cholecystitis
In the developmental stage of laparoscopic cholecystectomy it was considered 'unsafe' or 'technically difficult' to perform laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- HAC (NCT00746850)
- Testing
- early LC within 72 hours after the diagnosis with H (Harmonic), early LC within 72 hours after the diagnosis with MD (Monopolar Diathermy)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Bologna
Fast-track Protocol, Hip Fracture
IMPLICATION OF FAST-TRACK PROTOCOL FOR HIP FRACTURE FIXATION IN ALEXANDRIA UNIVERSITY HOSPITALS
The present study aims to evaluate the impact of fast-track protocol of hip fracture fixation within 48 hours on patients' mortality and morbidities.
- Conditions
- Fast-track Protocol, Hip Fracture, 30 Days Mortality
- Trial name
- NCT06881121
- Testing
- Fast-track protocol for hip fracture fixation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Surgical Wound Infection
Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Comparison between waterproof sterile dressing OPSITE Post-Op Visible, Smith \& Nephew, UK and PICO-7, Smith \& Nephew, UK in terms of inguinal surgical wound infection and complications after lower limb revascularization.
- Trial name
- PICO-Vasc (NCT04840576)
- Testing
- Regular waterproof sterile dressing., Prophylactic Negative Pressure Dressing
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Corporacion Parc Tauli
Sepsis, Lactate Blood Increase
Blood Lactate Level for Pre-hospital Orientation of Septic Shock
In the pre-hospital setting, the severity assessment of septic shock is essential to decide the optimal initial in-hospital level of care.
- Trial name
- LAPHSUS (NCT03831685)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hôpital Necker-Enfants Malades
Diabetes Mellitus, Type 2
Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients
The study aims to evaluate the effects of Insulin Degludec/Liraglutide on glycemic variability assessed by continuous glycemic monitoring with the function time in range, serum markers of inflammation, markers of endothelial…
- Trial name
- NCT05360537
- Testing
- Insulin Degludec / Liraglutide Injectable Product, Insulin Glargine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
COVID-19, Methylprednisolone
Investigation of Hospitalisation Times and Mortality According to Drug Dose in Patients Given Systemic Methylprednisolone With a Pre-diagnosis of Covid-19 Pneumonia; Retrospective Study
Aim:There is still not enough data to determine methylprednisolone treatment timing, dosage, duration of use and indication in Covid 19 pneumonia.
- Conditions
- COVID-19, Methylprednisolone, Pneumonia
- Trial name
- NCT04847687
- Testing
- methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
COPD, Interstitial Pneumonia
Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study
This study analyzes patients who underwent lung transplantation at the First Affiliated Hospital of Zhejiang University from 2017 to 2024, focusing on anesthesia's impact on post-op results.
- Conditions
- COPD, Interstitial Pneumonia, Bronchiectasis, Respiratory Failure
- Trial name
- NCT06922916
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Zhejiang University
Geriatric Patients, Emergencies
European Geriatric Emergency Departments Registry Study
Geriatric presentations to emergency services comprise a significant percentage of all emergency service presentations in Europe and it has been reported that 3-23% of all emergency service presentations from various regions of…
- Conditions
- Geriatric Patients, Emergencies, Length of Stay, Early Warning Score
- Trial name
- EGERS (NCT04680299)
- Where
- 7 sites in Croatia, France and 4 more
- Volunteers
- 3,000 people
- Sponsor
- Gazi University
Myocardial Infarction
Comparison of Information Recorded in MINAP, GPRD and HES: a CALIBER Study
Medical information is increasingly processed electronically. This study will describe the similarities and differences in the data recorded by different databases of electronic healthcare database.
- Trial name
- NCT01569139
- Where
- 3 sites in United Kingdom
- Volunteers
- 21,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Sars-CoV2
LILLE COVID RESEARCH NETWORK (Covid-19)
The Lille University Hospital developped a research objective common to all the services which took care of patients, "suspected patient", "possible case", "probable case" or "confirmed case" infected with SARS-CoV-2 by…
- Trial name
- LICORNE (NCT04475211)
- Where
- France
- Volunteers
- 757 people
- Sponsor
- University Hospital, Lille
Premature Birth
Study of the Short-term Mortality and Morbidity of Newborns Born at a Gestational Age <32 Weeks of Amenorrhea
An "outborn" birth is a premature birth that occurs in an unsuitable level center at the end of the child (unlike "inborn" births).
- Trial name
- OutBorn (NCT05150301)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Strasbourg, France
Infection Resistant to Drugs, Gram-Negative Bacterial Infection
Burden of Antibiotic Resistance in Gram-Negative Infections in Dutch Hospitals
This study aims to assess how large an additional disease burden and what extra costs are generated by antibiotic resistance in patients suffering from infections caused by gram-negative bacteria, such as Escherichia coli and…
- Trial name
- GRAND-ABC (NCT02007343)
- Where
- 8 sites in Netherlands
- Volunteers
- 3,895 people
- Sponsor
- UMC Utrecht
Myocardial Infarction
Quality and Safety of Initial Management for ST-segment Elevation Myocardial Infarction
This is a multicenter multidisciplinary study designed to investigate patient, provider, and system-related factors that are associated with the quality and safety of initial management for suspected ST-segment elevation…
- Trial name
- STEMI-Qual (NCT02788344)
- Testing
- Daily practice care for patients with suspected of STEMI
- Where
- France
- Volunteers
- 6,920 people
- Sponsor
- Centre Hospitalier Annecy Genevois