Clinical trials: InVitro Fertilization
InVitro Fertilization, Gonadotropins
rFSH vs rFSH+rLH in Dydrogesterone-Based Progestin Protocol: A Prospective Study
This study aims to compare two commonly used hormone treatments for women undergoing IVF. All participants will receive a stimulation protocol that includes dydrogesterone, a medication used to safely control natural hormone…
- Trial name
- DYG-GONA (NCT07348757)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Infertility, Male Infertility
To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.
The goal of this prospective, multicenter randomized controlled clinical trial is to evaluate whether the SwimCount Harvester microfluidic sperm preparation device can achieve equivalent or superior clinical outcomes compared to…
- Conditions
- Infertility, Male Infertility, InVitro Fertilization, Aneuploidy Rate
- Trial name
- NCT07369362
- Testing
- microfludics semen processing device
- Where
- United States
- Volunteers
- 1,600 people
- Sponsor
- MotilityCount aps
Ovarian Aging, In Vitro Fertilisation (IVF) Treatment
Follicular Fluid microRNAs in Ovarian Aging and Reproduction
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes.
- Conditions
- Ovarian Aging, In Vitro Fertilisation (IVF) Treatment, InVitro Fertilization, In Vitro Fertilization Outcome
- Trial name
- NCT07214246
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Central Florida
WHITE NOISE, INVITRO FERTILIZATION, PAIN, ANXIETY, COMFORT
White Noise and In-vitro Fertilizasyon
In vitro fertilization is the placement of embryos into the uterus with a catheter under ultrasound guidance after the fertilization of sperm and oocytes in a laboratory tube.
- Trial name
- NCT06996340
- Testing
- White noise group, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Yasemin Sökmen
Invitro Fertilization
Endometrial Injury and Implantation Rates Before First ICSI Cycle
Midluteal single endometrial strip will be taken using a Novak curett under general anasthesia to avoid discomfort and cramping and to proceed to cervical dilatation in case of forbidden cervix, the step that will be beneficial…
- Trial name
- NCT02660125
- Testing
- Endometrial scratch injury
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Psychiatric Disorder, Invitro Fertilization /Intracytoplasmic Spem Injection Failure
Psychiatric Disorders With Prolonged Infertility
Psychiatric disorders in women with prolonged infertility with or without IVF/ICSI failure will be included then a questionnaire will be applied plus psychiatric examinatins
- Trial name
- NCT03569215
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 324 people
- Sponsor
- Tanta University
Invitro Fertilization, Diminished Ovarian Reserve
Effect of Follicular Flushing in Patients With Mono-follicular Growth Undergoing In Vitro Fertilization
Retrieval of an oocyte from a follicle relies on the release of the cumulus-oocyte-complex (COC) from the follicular wall into the lumen, thereby allowing aspiration by a needle.
- Conditions
- Invitro Fertilization, Diminished Ovarian Reserve, Oocyte
- Trial name
- NCT03831542
- Testing
- direct follicular aspiration, follicular flushing
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Invitro Fertilization
Accuracy of Ultrasound Markers Versus Biochemical Markers in Prediction of Ovarian Response in Obese Women Undergoing IVF/ICSI Treatment
After detailed history and examination, long luteal protocol will be used for controlled ovarian hyperstimulation, so the patient will start treatment in day 21 of previous cycle, then in the early follicular phase of next cycle…
- Trial name
- NCT03684824
- Testing
- Long luteal phase GnRH agonist protocol, Gonadotropins
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Invitro Fertilization
Comparative Study Between ICSI Results in Transvaginal Ultrasound Guided Embryo Transfer and Transabdominal Ultrasound Guided Embryo Transfer
This prospective study will be conducted on 120 patients candidates for ICSI cycle and following the long protocol for controlled ovarian stimulation; the patients were randomly allocated in a 1:1 ratio to either group A; where…
- Trial name
- NCT03683043
- Testing
- Long GnRH agonist protocol, Embryo transfer
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Invitro Fertilization
Poor Responders Infertile Patients -A Great Clinical Challenge
infertile , poor responders patients who underwent ICSI. The participants were divided into 2 groups according to the starting dose of Gn stimulation. Group I started with 4 ampoules while group II started with 6 ampoules
- Trial name
- NCT03402620
- Testing
- Gonadotropins
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Cairo University
Invitro Fertilization
The Impact of Body Weight on Reproductive Outcomes in Poor Ovarian Responders in ICSI Cycles
Induction of ovulation cycle: 1. Gonadotrophines is started on day 2 with HMG(merional, IBSA) ,until the day of HCG administration(choriomon,IBSA10000IU) with starting dose 300 to 450iu. 2.
- Trial name
- NCT03457233
- Testing
- Gonadotropins, GNRH antagonist, Human chorionic gonadotropin Chorimon
- Where
- Egypt
- Volunteers
- 185 people
- Sponsor
- Cairo University
Invitro Fertilization
Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI
Patients will be divided into two groups Group A; patients using long protocol and freeze all embryos Group B; patients using antagonist protocol with fresh embryo transfer Patients will be carefully chosen according to a strict…
- Trial name
- NCT03118830
- Testing
- Triptorelin, cetrorelix, Recombinant Follicle Stimulating Hormone
- Where
- Egypt
- Volunteers
- 204 people
- Sponsor
- Cairo University
Invitro Fertilization
Value of Cabergoline and Low Dose Aspirin in Poor Responders Undergoing ICSI-ET With GnRH Agonist Flare-Up-Protocol
Ovarian stimulation will be done using the Microdose flare-up regimen. The patient will receive diluted doses of the GnRH agonist leuprolide acetate 40 µg, given subcutaneously twice daily.
- Trial name
- NCT03263299
- Testing
- cabergoline, Aspirin, GnRH agonist
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Invitro Fertilization
Embryoscope and Reproductive Outcome
cases with embyos cultured in the standard incubator and evaluated only by morphology are compared to cases with embryos continuously monitored by the embryoscope followed by embryo selection based on a multivariable model
- Trial name
- NCT02764255
- Volunteers
- 770 people
- Sponsor
- Ahmed Maged
Invitro Fertilization
Factors Associated With Pregnancy Loss in IVF Women
Maternal and clinical characteristics associated with spontaneous second-trimester pregnancy loss (between 12 1/7 and 23 6/7 weeks of gestation) will be assessed.
- Trial name
- NCT02383394
- Testing
- follow up antenatal care
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Invitro Fertilization
FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women
All women had normal uterine cavity determined by previous hysterosalpingography or hysteroscopy. Women with abnormally low Gn as hypothalamic hypogonadism , High LH as PCOS and women with abnormal endocrine functions as abnormal…
- Trial name
- NCT02674178
- Testing
- Invitro fertilization
- Where
- Egypt
- Volunteers
- 235 people
- Sponsor
- Cairo University
Infertility, Invitro Fertilization
Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure
Women with history of previous IVF cycle failure will be subjected to a fresh IVF cycle. At the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will…
- Trial name
- NCT02329197
- Testing
- Human Chorionic Gonadotropin (HCG)
- Where
- Egypt
- Volunteers
- 380 people
- Sponsor
- Mansoura University
Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome
Long Acting GnRH Antagonist in PCOS Women Undergoing IVF
PCOS is a common endocrinopathy affecting 5-10% of women in their reproductive age characterized by hyperandrogenism, chronic anovulation and polycystic ovaries.
- Conditions
- Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome, Invitro Fertilization
- Trial name
- NCT02084940
- Testing
- GnRH antagonist depot Degarelix
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bioroma
InVitro Fertilization
Telomeres and Reproduction in Women
The purpose of the study is to describe the relationship between leukocyte, granulose cell and polar body telomere length, telomere injury foci (TIFs), polarized light microscopy of oocyte spindles and their frequency in the eggs…
- Trial name
- NCT01576991
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of South Florida