Clinical trials: Inactivity, open to volunteers
Ulcerative Colitis (UC), Crohn's Disease
Stopping PPI Therapy in Inactive IBD
To investigate the feasibility of proton pump inhibitor (PPI) withdrawal in inflammatory bowel disease (IBD); the data collected will provide valuable information to inform a future multi-centre randomised controlled trial.
- Trial name
- STOP-IT (NCT07691138)
- Testing
- Continue PPI Therapy, Withdraw PPI Therapy
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Nottingham
Physical Inactivity, Sedentary Lifestlye
Roybal Via Habit Formation
This pilot study will develop and evaluate ViaHabit, a personalized walking intervention designed to promote physical activity habit formation among sedentary midlife adults (ages 45-65).
- Trial name
- Via Habit (NCT07848178)
- Testing
- ViaHabit
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Louisiana State University and A&M College
Head and Neck Neoplasms, Physical Inactivity
Preventive Physical Activity Intervention in Head and Neck Cancer
The study includes patients with tumors of the oropharynx, larynx and hypopharynx scheduled to receive radiotherapy with curative intent (+/- chemotherapy).
- Trial name
- NCT05432297
- Testing
- Preventive physical exercise
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Sahlgrenska University Hospital
Obesity, Physical Inactivity
Age and Insulin Resistance
Insulin resistance is a crucial factor for the development of type 2 diabetes and a major health problem for older adults. It is the principal mechanism by which obesity is considered to increase the risk for type 2 diabetes and…
- Conditions
- Obesity, Physical Inactivity, Aging
- Trial name
- AGIR (NCT01224886)
- Testing
- Physical activity
- Where
- 2 sites in Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Overweight and Obese Adults, Physical Inactivity
A 12-week Field Trial of the Movámonos Physical Activity Support Program
The objective of this study is to design and refine an activity support program, called Movámonos, for adults with overweight or obesity who speak Spanish.
- Trial name
- Movámonos (NCT07561996)
- Testing
- Movámonos Physical Activity Support Program
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
General Surgery, Perioperative Complication
Perioperative Impact of Physical Activity on Short- and Long-term Morbidity and Mortality
Over 300 million surgeries are performed globally every year. Complications after surgery - infections, cardiovascular conditions, postoperative pulmonary complications and renal impairment - affect survival and quality of life.
- Conditions
- General Surgery, Perioperative Complication, Perioperative Medicine, Physical Inactivity
- Trial name
- PeriopIPA (NCT06678360)
- Where
- Sweden
- Volunteers
- 180,000 people
- Sponsor
- Karolinska Institutet
Sedentary Behaviors, Core Muscle Weakness
Pilates for Sedentary Individuals
The global rise in physical inactivity represents an escalating public health crisis, with the proportion of insufficiently active adults projected to reach 35% by 2030.
- Trial name
- NCT07666919
- Testing
- Pilates exercise, Walking exercise
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Obesity, Physical Inactivity
Effects of Short Isokinetic Eccentric Resistance Training on Neuromuscular Induced Adaptations
The study compares the impact of isokinetic resistance training (RT) -induced neuromuscular adaptation following an 8-week short ECC ISO RT and CON ISO RT among obese, untrained women. The main question it aims to answer is: 1.
- Trial name
- NCT07407621
- Testing
- ECC ISO, CON ISO
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Metabolic Syndrome, Inactivity/Low Levels of Exercise
Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial
This study aims to evaluate the impact of public health interventions on changes in healthy lifestyle habits over time and their subsequent effects on health outcomes.
- Conditions
- Metabolic Syndrome, Inactivity/Low Levels of Exercise, Unhealthy Diet, Unhealthy Alcohol Use
- Trial name
- LifeHealth-RCT (NCT07314957)
- Testing
- Intervention of physical activity, Mediterranean Diet Education, Behavioral: Stress-Resilience Training
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Liver Transplant; Complications, Physical Inactivity
Preoperative Prehabilitation in Patients Planned for Liver Transplantation
The objective of this study is to determine the feasibility and effectiveness of a home-based multimodal prehabilitation program in patients anticipated to be waitlisted for LT.
- Trial name
- PRELIVERT (NCT06808945)
- Testing
- Prehabilitation program
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
tDCS, Physical Activity + tDCS
Influence of Physical Exercise on Neuroplasticity and Sensorimotor Networks in Older Adults
The purpose of this study is to investigate the influence of a single session of moderate aerobic exercise on motor cortex neuroplasticity in older adults, both alone and in combination with transcranial direct current…
- Conditions
- tDCS, Physical Activity + tDCS, Physical Inactivity + tDCS
- Trial name
- EXOPLASTIC (NCT07438808)
- Testing
- Aerobic Exercise, Physical Inactivity, Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Physical Inactivity, Overweight and Obesity
A Pilot Factorial Trial of an Integrated Lifestyle Intervention
This study plans to learn more about the feasibility and acceptability of integrating the Move physical activity support program within an existing lifestyle intervention program.
- Trial name
- NCT06116435
- Testing
- Prevent T2, Move group-based classes, Fitness Membership
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sedentary Behavior / Physical Inactivity, Aging
Effects of Different Amounts of Plyometric Exercise Without Jumping in Physically Inactive Older Adults
The goal of this clinical trial is to investigate whether different amounts of plyometric exercise without jumping can improve lower-limb muscle strength, power, and muscle and tendon mechanical properties in sedentary and/or…
- Trial name
- NJPT-OLDER (NCT07891000)
- Testing
- High-Volume Non-Jumping Plyometric Training, Low-Volume Non-Jumping Plyometric Training
- Volunteers
- 54 people
- Sponsor
- University of Americas - Chili
Physical Inactivity
Makoyoh'Sokoi - The Wolf Trail Program Expansion Project - Supporting Indigenous Women to Celebrate Good Health
During the MKS+ program participants complete health education modules that expose them to health information, a substantial portion of which relate to healthy nutrition and prevention, and on occasion to local healthcare…
- Trial name
- MKS+ (NCT05362435)
- Testing
- Physical activity-based wellness programs
- Where
- 7 sites in Canada
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Physical Inactivity, Phosphate Overload
Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity
Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal…
- Conditions
- Physical Inactivity, Phosphate Overload, Visceral Obesity
- Trial name
- NCT05147909
- Testing
- Sodium Phosphate, Sodium Chloride
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy Endurance Athlet, Inactive People
Effects of Exercise Timing on Sleep Quality
Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects.
- Trial name
- SLEEPCORE (NCT07322276)
- Testing
- Aerobic Exercise
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Leukemia, Physical Inactivity
Dyadic Physical Activity Intervention for Children Undergoing Cancer Treatment
The goal of this study is to learn if a parent-child dyadic physical activity (PA) intervention works to improve physical activity levels in children with leukaemia.
- Trial name
- DYAD-PA (NCT07737418)
- Testing
- Dyadic Physical Activity Intervention, Individual Intervention, Psychological Support
- Volunteers
- 198 people
- Sponsor
- The Hong Kong Polytechnic University
Depression, Physical Inactivity
Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2)
This study develops and tests a dynamic workplace-based depression intervention that is tailored to the specific social and behavioral needs of low-wage hospital service workers.
- Trial name
- NCT06753123
- Testing
- A workplace-based depression intervention for low-wage hospital workers
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- San Diego State University