Clinical trials: Incision Infection
Surgery, Surgical Site Infection
SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty
Comparing the growth of intra-operative tissue cultures of Cutibacterium Acnes after primary shoulder replacement when using a no-prep control group versus antimicrobial wound gel versus betadine applied to the skin layer after…
- Conditions
- Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
- Trial name
- NCT05919888
- Testing
- Povidone-Iodine, SURGX Wound Gel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Infections, Surgery
Study Looking at the Effect of Silverlon on Post Operative Wound Infections
This clinical study is a prospective, randomized, controlled trial of patients undergoing elective colorectal surgical procedures that receive an abdominal skin incision of at least 6 cm.
- Trial name
- NCT01143883
- Testing
- Silverlon, Standard of Care Dressing
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Jorge Marcet
Surgical Site Infection, Pancreaticoduodenectomy
Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy
Preoperative biliary drainage predisposes the bile to be contaminated with bacteria of the duodenum. These bacteria colonizing the bile are a potential source for surgical site infections after pancreaticoduodenectomy and many…
- Conditions
- Surgical Site Infection, Pancreaticoduodenectomy, Biliary Tract Infection Bacterial
- Trial name
- NCT05581017
- Testing
- Preoperative biliary drainage
- Where
- Finland
- Volunteers
- 376 people
- Sponsor
- Helsinki University Central Hospital
Colostomy Stoma, Ileostomy - Stoma
Needle-Aspirated Compression Dressing Following Ostomy Reversal
Negative pressure wound dressings have been studied and shown to have applications in decreasing rates of surgical wound infections.
- Conditions
- Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
- Trial name
- NCT03703661
- Testing
- Needle-Aspirated Negative Pressure Dressing, Control
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Skin Diseases, Surgical Site Infection
Surgical Hand Antisepsis With Propan-ol-1 60% Per Rubbing and Scrubbing
The present study evaluates the effects of to compare bactericidal efficacy using the reference antiseptic product propan-ol-1 60% using the hand rub method versus hand scrub method in order to test if pass the standard european…
- Trial name
- NCT04446923
- Testing
- Hand antisepsis by scrub
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Total Knee Replacement Surgery
Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
This study evaluates the effect of Iodine-impregnated self-adhesive plastic drapes (IIAD) on the quantity of skin bacteria, which is a known factor in the development of surgical site infections in orthopedic surgery.
- Trial name
- NCT02342561
- Testing
- Ioban 2 incision drape, 3M
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Vancomycin, Implantable Neural Stimulator
Intrawound Vancomycin Prophylaxis for Neural Stimulator
The implantable pulse generator (IPG) is a device that generates electrical current to stimulate the spine, heart, or brain for various chronic conditions.
- Conditions
- Vancomycin, Implantable Neural Stimulator, Deep Brain Stimulation, Surgical Site Infection
- Trial name
- IV-DIRT (NCT03221023)
- Testing
- Vancomycin Hydrochloride, Saline Solution
- Where
- Canada
- Volunteers
- 900 people
- Sponsor
- University of British Columbia
Colorectal Surgery, Surgical Wound Infection
A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection
The purpose of this study is to determine whether the gentamicin-collagen sponge is safe and effective for preventing surgical wound infections in patients undergoing colorectal surgery.
- Trial name
- NCT00600925
- Testing
- gentamicin-collagen sponge dipped in saline
- Where
- 39 sites in United States
- Volunteers
- 602 people
- Sponsor
- Innocoll
Surgical Site Infection
24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis
A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd generation cephalosporin…
- Trial name
- NCT04303390
- Testing
- Cefuroxime, Cefazolin, 24 hours
- Where
- Saudi Arabia
- Volunteers
- 568 people
- Sponsor
- Saud Al Babtain Cardiac Center
ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications
Closed Incision NPWT to Prevent Wound Complications Post-ECMO
Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden.
- Conditions
- ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications, Surgical Site Infection (SSI)
- Trial name
- PREVENT-ECMO (NCT07709546)
- Testing
- Prophylactic Closed-Incision Negative Pressure Wound Therapy, Standard Wound Dressing
- Volunteers
- 144 people
- Sponsor
- St. Antonius Hospital
Endovascular Procedures
Groin Wound Infection Rate Using Prevena Compared to Standard Dressing in Vascular Surgery Patients With High Risk
Evaluate wound healing using Prevena compared to standard dressings in high risk patients after vascular surgery.
- Trial name
- PREVENA (NCT03105154)
- Testing
- Prevena Dressing, Conventional Dressing
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- The Cleveland Clinic
Wound Infection
Supplemental Oxygen Reduces Surgical Infection
Supplemental perioperative oxygen has been reported to halve or double the risk of surgical wound infection. We tested the hypothesis that supplemental oxygen reduces infection risk following colorectal surgery.
- Trial name
- NCT00235456
- Testing
- Perioperative supplemental oxygen, Standard oxygen
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- The Cleveland Clinic
Surgical Site Infection
Study of the Incidence of Surgical Site Infections Developed by Patients Hospitalized in the Wards of a Large Teaching Hospital in Rome, Italy
The surgical departments of the hospital were included in the study on a rotational basis over a period of 5 months. All patients undergoing surgery during this period were enrolled in the study.
- Trial name
- NCT05788575
- Testing
- surgery
- Where
- Italy
- Volunteers
- 5,424 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Incisional Surgical Site Infections
Total Occlusive Ionic Silver-containing Dressing vs Mupirocin Ointment Application vs Conventional Dressing in Elective Colorectal Surgery: Effect on Incisional Surgical Site Infection
The patients were randomized into 3 groups: those patients undergoing a ionic silver-containing dressing (ISD) (Group 1), those undergoing a Mupirocin ointment application (MOA) (Group 2) and those using a conventional dressing…
- Trial name
- NCT02267122
- Testing
- ionic silver-containing dressing, Mupirocin ointment application
- Volunteers
- 147 people
- Sponsor
- Hospital General Universitario Elche
Infection Prophylaxis in Colo Rectal Surgery
Orally Administered Trimethoprim-sulfamethoxazole and Metronidazole as Prophylaxis of Infection Following Elective Colorectal Surgery
The current standard Swedish infection prophylaxis in colorectal surgery is intravenously administered cefuroxime and metronidazole. this combination is well studied.
- Trial name
- NCT00613769
- Testing
- trimethoprim-sulfamethoxazole + metronidazole, cefuroxime and metronidazole
- Where
- 6 sites in Sweden
- Volunteers
- 1,073 people
- Sponsor
- Halmstad County Hospital
Postoperative Surgical Site Infections
Negative Pressure Wound Therapy Use to Decrease Surgical Nosocomial Events in Colorectal Resections
The purpose of this study is to determine, in patients who undergo an elective colorectal resection through a midline laparotomy incision, whether the use of negative pressure wound therapy (NPWT) applied to the site of the…
- Trial name
- NEPTUNE (NCT02007018)
- Testing
- Negative Pressure Wound Therapy, Usual Care of Surgical Wound
- Where
- 2 sites in Canada
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Surgical Site Infection
Prophylactic Antibiotic in Subtalar Fusion Surgery
Assessment of surgical site infection when using postoperative antibiotic prophylaxis in subtalar fusion surgery 24hours versus 5 days
- Trial name
- NCT06527989
- Testing
- Ceftriaxone 2000 mg
- Volunteers
- 102 people
- Sponsor
- Assiut University
Abscess, Pain
IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D
The general objective of this study is to determine whether intranasal ketamine should be incorporated into formulary as an option to treat pain during minor procedures in the pediatric emergency department.
- Trial name
- NCT02635282
- Testing
- intranasal ketamine, intranasal fentanyl, intranasal midazolam
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Infection; Cesarean Section, Surgical Wound Infection
Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity
Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are…
- Conditions
- Infection; Cesarean Section, Surgical Wound Infection, Endometritis
- Trial name
- Peri-Op (NCT00603603)
- Testing
- 80% inhaled oxygen via non-rebreather mask, 30% inhaled oxygen via nasal cannula
- Where
- United States
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Surgical Site Infection
Effect of Vitamin E Ointment on Incisional SSI in Colorectal Surgery
A prospective, randomized study was performed. The patients were randomized into 2 groups: those patients undergoing subcutaneous vitamin E ointment application (Group 1) and those patients who not (Group 2).
- Trial name
- NCT02820948
- Testing
- Vitamin E ointment application
- Volunteers
- 108 people
- Sponsor
- Hospital General Universitario Elche