Clinical trials: Incisional Hernia/Prevention and Control
Incisional Hernia/Prevention and Control
Prometheus: Prophylactic Mesh After OLtx for Hernia Reduction Study.
A multicenter prospective, consecutive case series study, on the use of a bio-absorbable mesh for prevention of incisional hernia, in high risk patients, after orthotopic liver transplantation.
- Trial name
- PROMETHEUS (NCT07744230)
- Testing
- mesh
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Incisional Hernia, Pelvic Cancer
Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer
The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual…
- Trial name
- VRAM (NCT00647569)
- Testing
- Mesh repair, Conventional facial closure
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Incisional Hernia
Prophylactic Mesh in Cytoreductive Surgery
Evaluate the effectiveness of mesh reinforcement in high-risk patients to prevent incisional hernia.
- Trial name
- NCT03953365
- Testing
- Prophylactic Mesh
- Volunteers
- 66 people
- Sponsor
- Hospital Universitario Fundación Alcorcón
Peritonitis, Incisional Hernia
Prophylactic Mesh Implantation in Patients With Peritonitis for the Prevention of Incisional Hernia
In patients undergoing laparotomy, the incidence of abdominal wall related complications such as incisional hernia is very high.
- Conditions
- Peritonitis, Incisional Hernia, Surgery
- Trial name
- PerProMe (NCT01802164)
- Testing
- A non-absorbable composite mesh (Ethicon Physiomesh)
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Incisional Hernia, Emergency Laparotomy
Preemer Trial - Prophylactic Mesh Versus no Mesh in the Midline Emergency Laparotomy Closure for Prevention of Incisional Hernia: a Multi Center, Double-blind, Randomized Controlled Trial
244 patients, who have an emergency midline laparotomy for any gastrointestinal reason, will be randomized in a 1:1 ratio either to mesh group with a retrorectus prophylactic self-gripping mesh or to control group with 4:1 small…
- Conditions
- Incisional Hernia, Emergency Laparotomy, Midline Laparotomy, Hernia Prevention
- Trial name
- NCT04311788
- Testing
- Prophylactic self gripping mesh, Slowly absorbable continuous monofilament suture
- Where
- 7 sites in Finland
- Volunteers
- 109 people
- Sponsor
- University of Oulu
Incisional Hernia
Usefulness of a Prothetic Absorbable Mesh in Incisional Hernia Prevention After Midline Laparotomy
Background: Development of an incisional hernia is one of the most frequent complications of midline laparotomies requiring reoperation.
- Trial name
- PREBIOUS (NCT02208557)
- Testing
- Reinforcement with Absorbable Mesh, Control CT, Clinical Follow Up
- Where
- 6 sites in Spain
- Volunteers
- 488 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Suture Techniques, Wound Closure Techniques
Small Bites Vs Large Bites Abdominal Midline Incisional Closure
The goal of this trial is to compare the effectiveness of small bite versus large bite abdominal incision closure in emergency settings. It will also evaluate the safety and outcomes of each technique.
- Conditions
- Suture Techniques, Wound Closure Techniques, Laparotomy/Standerds, Surgical Wound Dehiscence
- Trial name
- NCT07154277
- Testing
- Small bite closure, Large bite closure
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
Incisional Hernia
A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis
Currently, no standard of care exists to prevent incisional hernias (IH). This study will compare how frequently IH develop in standard abdominal closures vs. abdominal closures with dHACM added.
- Trial name
- NO-HERNIA (NCT04417140)
- Testing
- dHACM (AmnioWrap)
- Where
- United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Open Abdomen, Incisional Hernia
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy
The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen…
- Conditions
- Open Abdomen, Incisional Hernia, Definitive Fascial Closure, Emergency Abdominal Surgery
- Trial name
- SHIELD (NCT07835334)
- Testing
- Definitive Fascial Closure Without Prophylactic Mesh, Prophylactic Onlay Mesh Placement
- Volunteers
- 30 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Incisional Hernia
Hernia-Prophylaxis in Acute Care Surgery H-PACS
Incisional hernia is a common complication in visceral surgery and varies between 11 and 26% in the general surgical population.
- Trial name
- H-PACS (NCT03090022)
- Testing
- Strattice, Single running suture of abdominal fascia
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University