Clinical trials: Incisional Hernia of Anterior Abdominal Wall
Incisional Hernia, Umbilical Hernia
Laparoscopic or Conventional Mesh Repair of Incisional and Umbilical Hernia
The aim of this study is to compare immediate and long-term (24 months) results of laparoscopic and open mesh repair of incisional and umbilical hernia.
- Trial name
- EVENTRALAP (NCT00970515)
- Testing
- Laparoscopic mesh hernia repair, Open anterior approach
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hernia, Ventral
The Use of Local Hemostatic in Patients With Large Incisional Hernias
Design of a simple blind randomized controlled trial study. Large incisional hernia repair with use of local hemostatic Hemoblock
- Trial name
- NCT04222517
- Testing
- Incisional hernia repair by the mesh implant in sublay retromusuclar position, Incisional hernia repair by the mesh implant in sublay retromusuclar position with using a local hemostatic Hemoblock
- Where
- Russia
- Volunteers
- 66 people
- Sponsor
- Nijznevartovsk County Clinical Hospital
Ventral Incisional Hernia, Abdominal Wall Hernia
Robotic Versus Open Comparison in the Surgical Treatment of Wide Abdominal Wall heRnias (ROCSTAR)
In the treatment of ventral incisional hernias, a mesh repair in the retromuscular plane is considered as the gold standard. To allow for adequate medialization of the fascial borders and a complete closure of the defect in case…
- Trial name
- ROCSTAR (NCT05575141)
- Testing
- incisional hernia repair
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Ventral Hernia
Prevena Incision Management System Wound Care
Comparison of ventral hernia repair using standard wound care versus Prevena.
- Trial name
- NCT02953769
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- AdventHealth
Ventral Incisional Hernia
Quality Control of Ventral Hernia Surgery by Prospective Registration
Quality Control of ventral hernia surgery in 21 Belgian hospitals by prospective registration in close collaboration with the Danish Hernia Database.
- Trial name
- NCT04624100
- Testing
- Hernia repair
- Volunteers
- 5,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Incisional Hernia, Pelvic Cancer
Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer
The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual…
- Trial name
- VRAM (NCT00647569)
- Testing
- Mesh repair, Conventional facial closure
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Hernia Abdominal Wall, Botox Injection
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the…
- Conditions
- Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome
- Trial name
- PRETOX (NCT07220382)
- Testing
- OnabotulinumtoxinA Injection, OnabotulinumtoxinA, 0.9 % Normal Saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Cleveland Clinic
Ventral Incisional Hernia
SUTURE TYPE AND RECURRENCE RISK AFTER INCISIONAL HERNIA REPAIR
Incisional hernia is a common condition after abdominal surgery and is often associated with pain, impaired physical function, and reduced quality of life.
- Trial name
- TAFAR (NCT07891091)
- Testing
- Suturing of hernia defect with non-absorbable suture, Suturing of hernia defect with slowly absorbable suture
- Where
- Sweden
- Volunteers
- 980 people
- Sponsor
- Ersta Diakoni
Ventral Hernia
Biological Meshes in Infected Fields: a Randomized Controlled Trial
The SIMBIOSE trial is a large multicenter phase III prospective randomized controlled single blinded trial comparing the use of biological mesh versus traditional wound care without biological mesh in patients with an infected…
- Trial name
- SIMBIOSE (NCT01594450)
- Testing
- Biological mesh, without biological mesh
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Lille
Ventral Hernia, Incisional Hernia
Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair
The goal of this clinical trial is to learn if cryoneurolysis, a targeted cold therapy applied to nerve branches, can relax the muscles of the abdomen to facilitate surgical repair of abdominal wall hernias.
- Conditions
- Ventral Hernia, Incisional Hernia, Hernia, Hernia Abdominal Wall
- Trial name
- NCT07874724
- Testing
- Cryoneurolysis
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of South Florida
Hernia, Ventral Hernia Repair
Complication Rate of Onlay vs Sublay Mesh Repair in Incisional Hernia
This randomized controlled trial was conducted at the Department of Surgery, Hayatabad Medical Complex, Peshawar. Eligible patients with incisional hernia were randomized into two parallel groups: sublay mesh repair and onlay…
- Conditions
- Hernia, Ventral Hernia Repair, Incisional Hernia Repair, Abdominal Wall Hernia
- Trial name
- NCT07401446
- Testing
- Sublay Mesh Repair, Onlay Mesh Repair
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Incisional Ventral Hernia
Cytokine Response to Abdominal Wall Reconstruction
This is a prospective, observational translational study of patients undergoing major abdominal wall reconstruction with primary fascial closure.
- Trial name
- NCT07422584
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Ventral Hernia, Incisional Hernia
oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias
This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair…
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Defect
- Trial name
- PRIOR (NCT06364306)
- Testing
- Robotically-assisted ventral hernia repair (RVHR), Open ventral hernia repair (OVHR)
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Ventral Incisional Hernia
Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement
Prospective, multicenter, observational study to evaluate performance of GORE® BIO-A® Tissue Reinforcement when used to reinforce midline fascial closure in single-staged open complex ventral incisional hernia repair.
- Trial name
- COBRA (NCT01325792)
- Testing
- GORE® BIO-A® Tissue Reinforcement
- Where
- 9 sites in United States, Netherlands
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Ventral Hernias, Incisional Hernias
Antimicrobial Hernia Repair Device
This prospective early feasibility clinical study will collect information regarding the safety and efficacy of the Cook® Antimicrobial Hernia Repair Device to reinforce soft tissue during ventral or incisional hernia repair in…
- Trial name
- NCT02730936
- Testing
- Antimicrobial Hernia Repair Device
- Sponsor
- Cook Group Incorporated
Hernia Incisional Ventral
LIQUIBAND FIX8® for Ventral Incisional Hernia
This study is designed to evaluate the safety and performance of device LiquiBand FIX8 Open hernia mesh fixation device. The use of this device is not experimental, as it is already approved for use in the EU (CE-marked).
- Trial name
- LBF8-03 (NCT07295379)
- Testing
- LIQUIBAND FIX8
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Advanced Medical Solutions Ltd.
Hernia, Ventral, Incisional Hernia
A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair
The objective of this study is to collect additional data on safety, performance and effectiveness of Phasix™ ST in subjects receiving laparoscopic ventral or incisional hernia repair at high risk for surgical site occurrence…
- Trial name
- ATLAS (NCT02712398)
- Testing
- Phasix™ ST
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Obese Adults, Hernia Abdominal Wall
Tirzepatide-Based Prehabilitation Before Elective Ventral and Incisional Hernia Repair in Patients With Obesity
This study evaluated whether a 16-week weight-loss program using tirzepatide before elective ventral and incisional hernia surgery could improve surgical readiness and outcomes in patients with obesity.
- Conditions
- Obese Adults, Hernia Abdominal Wall, Prehabilitation
- Trial name
- NCT07638592
- Testing
- Tirzepatide prehabilitation
- Where
- Italy
- Volunteers
- 91 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Ventral Hernia, Umbilical Hernia
Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?
The purpose of this study is to determine if a Transabdominal Plane Block will decrease patient pain and pain medication use after a laparoscopic ventral (ventral, umbilical, incisional) hernia repair with mesh.
- Conditions
- Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications
- Trial name
- NCT02007096
- Testing
- Transabdominal Plane Block, Non Transabdominal Plane Block
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai