Clinical trials: Incisions, Surgical
Functional Disturbance as Result
A Clinical Study to Compare Functional Outcomes After Surgery Using a Transverse or Longitudinal Surgical Incision in the Skin.
Trigger finger is a common pathology in the hand. Patients suffer from pain and depending on which tasks, patients have difficulty to perform them.
- Trial name
- NCT06267105
- Testing
- Longitudinal incision, Transverse incision
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Corporacion Parc Tauli
Surgical Site Infection
SMS-Based Follow-Ups to Improve Post-Discharge Surgical Outcomes
The purpose of this study is to determine whether low-cost Short Message Service (SMS)-based follow-up medication reminders and surveys for surgical site infection (SSI) reporting can improve outcomes by increasing medication…
- Trial name
- NCT03161262
- Testing
- SMS-based reminders
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Emory University
Thyroid Disease, Parathyroid Disease
Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery
The effectiveness of antimicrobial prophylaxis (AMP) for prevention of surgical site infection (SSI) following thyroid and parathyroid surgery remains uncertain.
- Trial name
- Ito-RCT1 (NCT01805856)
- Testing
- PIPC piperacillin sodium, CEZ, cefazolin sodium
- Where
- Japan
- Volunteers
- 2,164 people
- Sponsor
- Ito Hospital
Surgical Procedures, Minimally Invasive
Comparison of Ivor Lewis and Tri-incision Approaches for Patients With Esophageal Cancer
Esophagectomy for esophageal cancer is a technically complex procedure which is associated with high perioperative mortality, even in high volume centers[1].
- Conditions
- Surgical Procedures, Minimally Invasive, Operative, Esophageal Neoplasms
- Trial name
- NCT02017002
- Testing
- Ivor Lewis, Tri-incision
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Arthropathy, Incision, Surgical
Approach Modification for Total Knee Arthroplasty in Morbidly Obese Patients
The study provides a detailed description of a smaller incision with better visualization in total knee arthroplasty operations
- Conditions
- Arthropathy, Incision, Surgical, Obesity, Morbid
- Trial name
- NCT05840705
- Testing
- Small curved incision with apex lateral
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Surgical Wound
RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)
The objective of this trial is to demonstrate the safety and effectiveness of the Cardiva VASCADE™ Vascular Closure System (VCS) in sealing femoral arterial access sites.
- Trial name
- RESPECT (NCT01297322)
- Testing
- Manual compression, Cardiva VASCADE™ Vascular Closure System
- Where
- 21 sites in United States, Australia
- Volunteers
- 420 people
- Sponsor
- Cardiva Medical, Inc.
Surgical Site Infection, Antibiotic Resistant Infection
Antibiotic Stewardship Program in Pancreatic Surgery: a Multicenter Time Series Analysis (BIOSTEPS).
Rationale: Surgical site infection (SSI) is one of the most frequently reported postoperative complication, occurring in up to one-third of patients.
- Trial name
- BIOSTEPS (NCT04199494)
- Testing
- Antibiotic Stewardship Program
- Where
- 2 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Infection, Bacterial, Wound Infection
DACC in the REduction of Surgical Site INfection
Surgical site infection is an infection at a place in the body where surgery has taken place, and has been reported in around 5% of people undergoing an operation. In vascular surgery, infection rates are as high as 30%.
- Conditions
- Infection, Bacterial, Wound Infection, Wound Infection, Surgical, Surgical Incision
- Trial name
- DRESSINg (NCT02992951)
- Testing
- DACC-Coated Post Operative Dressing
- Where
- United Kingdom
- Volunteers
- 722 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Surgical Site Infection
Randomized Controlled Trial to Evaluate the Optimal Timing of Surgical Antimicrobial Prophylaxis
Surgical site infections (SSI) are the most frequent hospital acquired infections in patients who underwent surgery. With regards to the increasing financial restraint in patient care, the socio-economic burden of SSI in the…
- Trial name
- NCT01790529
- Testing
- Early administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in anesthetic room (75 to 30 minutes prior to skin incision), Late administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in the operating theatre (within 30 minutes prior to skin incision)
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Hypothermia
Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
The application of active warming to patients whether awake or under general anesthesia has been proven safe in numerous studies and it is common practice to use warmers.
- Trial name
- NCT02177903
- Testing
- Bair Paws Patient Adjustable Warming System
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Solventum US LLC
Gynecological Surgery
Assessment of Changes in Vaginal Microbiota Profiles Before and After Vaginal Urogynecologic Surgery
Several studies have shown interactions between vaginal microbiota and post-surgical evolution. A study conducted by our team showed a tendency for patients with complications to have a greater diversity of vaginal microbiota.
- Trial name
- VAGIBIOTE (NCT04301401)
- Testing
- Vaginal swabs, Stool samples, Urine samples
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Skin Cancer Face, Surgical Incision
Exploratory Prospective of Experienced by Patients in the Surgery of Skin Cancers of the Face in Interventional Dermatology Department
Surgery is the first-line treatment of localized skin cancers. Knowledge on the patient's psychological experience is limited. Therefore, the psychological impact on patients before, during and after surgery can be…
- Trial name
- VECUCHIR (NCT04336371)
- Testing
- Self-administered questionnaires
- Where
- France
- Volunteers
- 98 people
- Sponsor
- University Hospital, Bordeaux
Laparotomy, Incisional Hernia
Clinical Performance and Safety of Suture-TOOL
The goal of this single arm intervention study is to investigate the safety and performance of a suturing device for closure of the midline incision after open abdominal surgery.
- Conditions
- Laparotomy, Incisional Hernia, Wound Infection, Closure Technique
- Trial name
- NCT05695157
- Testing
- Suture-TOOL
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Suturion AB
Surgical Wound Infection
NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies
This randomized trial will use a Negative Pressure Wound Therapy device or standard wound closure, in participants with gastrointestinal neoplasms, to measure the rate of surgical site infections
- Trial name
- NCT04955730
- Testing
- Negative Pressure Wound Therapy
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Retinal Perforations, Myopia, Degenerative
Corneal Flap Transplantation for Macular Hole Repair of High Myopia
The goal of this clinical trial is to learn about an innovative surgical technique for macular hole repair. This technique is for patients with high myopia using pars plana vitrectomy (PPV) combined with corneal flap…
- Trial name
- NCT05875909
- Testing
- corneal flap transplantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First People's Hospital of Hangzhou
Wound Surgical, Diabetes
Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty
This study is a single-center, prospective, randomized, open-label clinical trial evaluating three commercially available closed-incision negative pressure wound therapy (ciNPWT) devices: NPseal, PICO, and Prevena, in adult…
- Conditions
- Wound Surgical, Diabetes, Obesity, Chronic Kidney Diseases
- Trial name
- NCT07770633
- Testing
- NP Seal, PICO, Prevena
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Wound, Re-Epithelialization
Phenytoin in the Healing of Clean Surgical Wounds
The purpose of this study is to investigate the potential healing properties of phenytoin. The investigators will use the donor site of a split skin thickness graft (SSTG) to model a basic wound in a randomized controlled trial…
- Trial name
- NCT02413658
- Testing
- Phenytoin, Sugar solution
- Where
- Cambodia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Surgical Center, Cambodia
Postoperative Pain, Cesarean Section
Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune…
- Conditions
- Postoperative Pain, Cesarean Section, Wound Heal
- Trial name
- NCT05840406
- Testing
- Postoperative pain management with acetaminophen, Bilateral TAP Block with levobupivacaine, Bilateral TAP Block with levobupivacaine and dexmedetomidine
- Where
- Croatia
- Volunteers
- 105 people
- Sponsor
- University Hospital Sestre Milosrdnice
Wound Surgical, Wound Infection
PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds
Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. This study is taking place to investigate if Negative Pressure Wound Therapy (NPWT) dressings reduces Surgical Site Infections, post…
- Conditions
- Wound Surgical, Wound Infection, Cosmesis
- Trial name
- PROPEL-2 (NCT05977816)
- Testing
- Negative Pressure Wound Therapy, Standard wound dressing
- Where
- 10 sites in Ireland
- Volunteers
- 2,000 people
- Sponsor
- Royal College of Surgeons, Ireland
Laparotomy, Suture; Complications, Mechanical
DuraMesh Laparotomy Study
This is a multisite randomized control proof-of-concept trial to evaluate the safety of Duramesh laparotomy closure in the trauma and emergency laparotomy setting.
- Conditions
- Laparotomy, Suture; Complications, Mechanical, Hernia Incisional
- Trial name
- NCT03966768
- Testing
- Duramesh suturable mesh for laparotomy closure, Conventional suture for laparotomy closure
- Sponsor
- Mesh Suture Inc.
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