Clinical trials: Incisions, Surgical
Pain, Acute
Optimal Timing of Parasternal Intercostal Nerve Block Application for Acute Pain Management in Cardiac Surgery
Patients experiencing pain after undergoing cardiac surgery may also experience prolonged immobilization, insufficient respiratory functions, and the inability to cough due to median sternotomy.
- Trial name
- NCT05363540
- Testing
- pre-incisional parasternal intercostal block, post-incisional parasternal intercostal block
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Benha University
Surgical Incision
Comparison of NOSE and Conventional Methods in Laparoscopic Right Colon Surgery
Laparoscopic right hemicolectomy (LRH) is an accepted surgical procedure for several right sided colonic pathologies. Recently the advantages of the intracorporeal ileotransversostomy over the extracorporeal anastomosis is…
- Trial name
- NCT03487289
- Testing
- natural orifice
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Inonu University
Infection Secondary to Surgical Procedure
Antibiotic Prophylaxis in Gynecologic Laparoscopy
Laparoscopy is a surgical procedure indicated for most gynecological pathologies and presents numerous advantages over laparotomy, among them lower rates of surgical site infection and less comorbidity feverish.
- Trial name
- NCT01991834
- Testing
- gynecologic laparoscopy, Cefazolin
- Where
- 2 sites in Brazil
- Volunteers
- 114 people
- Sponsor
- Universidade do Vale do Sapucai
Cutaneous Ulcer, Diabetic Ulcer
Dermacyte® Liquid for Treatment of Cutaneous Ulcers and Wounds
The objective of this study is to make Dermacyte Liquid available on an expanded access basis to treat cutaneous ulcers and wounds refractory to initial treatment or that do not have adequate alternative treatments.
- Conditions
- Cutaneous Ulcer, Diabetic Ulcer, Surgical Wound Dehiscence, Burns - Multiple
- Trial name
- NCT06730022
- Testing
- MTX-001 (Dermacyte Liquid)
- Where
- United States
- Sponsor
- Merakris Therapeutics
Surgical Wound Infection
Multicenter Study Protocol: Research on Evaluation and Detection of Surgical Wound Complications with AI-based Recognition. (REDSCAR-trial)
The increasing use of telemedicine in surgical care has demonstrated significant poten-tial for improving patient outcomes and optimizing healthcare resources.
- Trial name
- REDSCAR (NCT06771726)
- Testing
- RedScar App
- Where
- 5 sites in Spain
- Volunteers
- 168 people
- Sponsor
- Universitat de les Illes Balears
Tissue Expander Based Breast Reconstruction
Local Antibiotic Concentrations With Tissue Expanders in Breast Reconstruction
Infections after tissue expander breast reconstruction can lead to pain, additional surgeries, and loss of the reconstruction. This study will compare two types of antibiotic carriers used during surgery to help lower the risk of…
- Trial name
- NCT07339215
- Testing
- Antibiotic loaded calcium sulfate beads, Polymethylmethacrylate antibiotic disc
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Acute Lithiasic Cholecystitis Grade I or II, Symptoms Lasting for Less Than 5 Days
Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis
Assess whether postoperative antibiotics after cholecystectomy for acute lithiasic cholecystitis little or moderately severe, is effective and therefore justified.
- Conditions
- Acute Lithiasic Cholecystitis Grade I or II, Symptoms Lasting for Less Than 5 Days, Required Cholecystectomy, Preoperative Amoxicillin Clavulanic Acid for at Most 5 Days
- Trial name
- ABCAL (NCT01015417)
- Testing
- Amoxicillin clavulanic acid, No medication
- Where
- 21 sites in France
- Volunteers
- 414 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Child Delivery Using an Elective C- Section
Evaluation of the BioWeld1 System as a Method for Surgical Incision Closure
The purpose of this study is to assess the safety and performance of the BioWeld1 System procedure for surgical incision closure of the skin in women scheduled for elective C-section procedure.
- Trial name
- NCT01709240
- Testing
- BioWeld1 System
- Where
- Israel
- Sponsor
- IonMed Ltd
Non-small Cell Lung Cancer, Renal Cell Carcinoma
Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma
This is a pilot study of biomarker evaluation and safety of pre-incisional ketorolac for patients undergoing surgical resection for non-small cell lung cancer and renal cell carcinoma.
- Trial name
- NCT04495894
- Testing
- Preoperative Ketorolac
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emory University
Surgical Wound
The Closer Trial: A Safety and Efficacy Study of the Rex Medical Vascular Sealing System
The objective of this trial is to demonstrate the safety and effectiveness of the Rex Medical Closer Vascular Sealing System in sealing femoral arterial access sites.
- Trial name
- Closer (NCT02136004)
- Testing
- Closer VSS
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rex Medical
Periodontitis, Periodontal Diseases
Three Types of Papilla Incision in Periodontal Surgery
Three types of papilla incision in periodontal reconstruction techniques will be compared.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket
- Trial name
- NCT06428149
- Testing
- Midline interproximal soft-tissue incision, Marginal approach by palatal incision, Minimally invasive surgical technique
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Murcia
Primary Open-angle Glaucoma
GORE Glaucoma Drainage Implant Clinical Study Dominican Republic
The objective of this early feasibility clinical study is to evaluate the safety and effectiveness of several different GORE Glaucoma Drainage Implant configurations in subjects with primary open-angle glaucoma that is…
- Trial name
- NCT05557058
- Testing
- Gore Glaucoma Device Implant (GORE GDI)
- Where
- Dominican Republic
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Total Knee Replacement
Comparison of Surgical Site Infection After Skin Closure by Prolene or Staples in Bilateral Knee Arthroplasty Patients
Knee arthroplasty also known as the total knee replacement is an orthopedic surgical procedure done to resurface the knee that has been severely damaged by arthritis.
- Trial name
- NCT04492852
- Testing
- Polypropylene (PROLENE) sutures, Staple Sutures
- Volunteers
- 82 people
- Sponsor
- Indus Hospital and Health Network
Rheumatoid Arthritis
Anti-TNFα Use During Elective Foot and Ankle Surgery in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a frequent inflammatory arthritis that can lead to severe joint deformity and often requires orthopaedic surgical interventions.
- Trial name
- NCT02242474
- Testing
- Anti-TNF suspended perioperatively, Anti-TNFα continued perioperatively
- Where
- Canada
- Volunteers
- 660 people
- Sponsor
- CHU de Quebec-Universite Laval
Surgical Incision
Does Disinfection of the Subcutaneous Tissue Reduce Contamination of the Operating Field With P. Acnes?
Propionibacterium acnes is a pathogen commonly identified in postoperative shoulder infections. A recent study has shown that P.
- Trial name
- Elec_cautery (NCT04250649)
- Testing
- subcutaneous tissue disinfection
- Where
- Switzerland
- Volunteers
- 105 people
- Sponsor
- Hôpital du Valais
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection
Infection after spinal surgery is one of the serious complications. Spinal surgery infection can cause high morbidity, mortality, and costs.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Scoliosis Lumbar Region, Lumbar Spondylolisthesis
- Trial name
- NCT04341831
- Testing
- Teicoplanin
- Volunteers
- 120 people
- Sponsor
- Bezmialem Vakif University
Osteoarthritis, Knee, Osteoarthritis, Hip
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing…
- Trial name
- NCT07439575
- Testing
- Barbed Suture Wound Closure, Conventional Suture Wound Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bahattin Kemah
Surgical Site Infections, ARSC Motivation Model
The Effect of an ARCS Model-Based Escape Room Simulation on Nursing Students' Knowledge, Motivation, and Self-Efficacy Regarding Surgical Site Infections
The study is designed as a randomized controlled trial with an experimental and control group, using a pre-test, post-test, and follow-up test design.
- Conditions
- Surgical Site Infections, ARSC Motivation Model, Escape Room Simulation
- Trial name
- NCT07551973
- Testing
- Escape Room Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
C.Surgical Procedure; Disruption of Wound, Suture
Use of Stratafix Symmetric™ to Prevent Incisional Hernia in Gastrointestinal and Abdominal Surgery
Comparing the use of Stratafix Symmetric™ sutures to standard laparotomy closure sutures.
- Trial name
- STRATA-G (NCT06063577)
- Testing
- Stratafix suture, Standard of care suture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- West Michigan Cancer Center
Surgical Site Infection
Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
We are investigating outcome of antibiotic coated vicryl versus non coated vicryl in terms of rate of surgical site infection and lebgth of hospital stay in children after lalaprotomy for perforated viscera.
- Trial name
- NCT06129773
- Testing
- antibiotic coated vicryl used for fascial closure
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Muhammad Adeel Ashiq
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