Clinical trials: Incisions, Surgical
Surgical Procedure, Unspecified, Soft Tissue Infections
Three-dimensional Bone Regeneration Using Custom-made Meshes With and Without Collagen Membrane
The presence of alveolar ridge deficiencies is considered major limitation to achieve an implant-prosthetic restoration with high aesthetics and stability over time.
- Conditions
- Surgical Procedure, Unspecified, Soft Tissue Infections, Surgical Wound Dehiscence, Bone Density
- Trial name
- NCT04286334
- Testing
- Bone augmentation with cad-cam laser-sintered mesh
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- GBR Academy
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Upper Gastrointestinal Surgery, Post-operative Analgesia
Comparison of Continuous Wound Catheter Infusion Versus Continuous Epidural Infusion in Abdominal Surgery
Comparison of efficacy in management of pain in abdominal surgery between epidural versus wound infusion catheter {catheter placed within the incision site}
- Conditions
- Upper Gastrointestinal Surgery, Post-operative Analgesia, Wound Infusion Catheter, Upper Midline Incision
- Trial name
- NCT02782767
- Testing
- Wound catheter infusion, Epidural infusion
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Operation Wound; Infection, Bacterial Infections
Nudging Effect of Timer on Surgical Rub
To study whether a device has a nudging effect on the time spend on surgical rub.
- Conditions
- Operation Wound; Infection, Bacterial Infections, Surgical Procedure, Unspecified
- Trial name
- NCT04609384
- Testing
- Alcohol rub timer device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Sygehus Lillebaelt
Surgical Incision
Fractional Radiofrequency for Reduction of Surgical Scar Formation
Safety and Efficacy of Fractional Radiofrequency for the Reduction of Surgical Scar Formation
- Trial name
- NCT05897723
- Testing
- Fractional Radiofrequency
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Wound Healing, Surgical Wound
Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction
Skin cancers such as basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma lesions that develop on the head and neck are treated by Mohs surgery or wide local excision to remove all tumor cells and preserve the…
- Trial name
- NCT06634030
- Testing
- RhPDGF-BB, Saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University Medical Center
Appendicitis, Cholecystitis
NOVOsyn® for Trocar Incision After Laparoscopic Appendectomy and Cholecystectomy
The aim of this study is to evaluate if the application of a Chlorhexidine coated suture (Novosyn® CHD) will reduce the colonization of bacteria in comparison to an uncoated suture (Novosyn®) used for the closure of trocar wounds…
- Trial name
- NOVOTILAC (NCT04033211)
- Testing
- Novosyn® CHD for fascia and skin closure, Novosyn® for fascia and skin closure
- Where
- 4 sites in Germany, Spain
- Volunteers
- 316 people
- Sponsor
- Aesculap AG
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Gastric Cancer, Surgical Wound Infection
Fatigue and QoL Among Gastric Cancer Patients Undergoing Abdominal Surgery
Background: Cancer-related fatigue (CRF), one of the indicators of QoL, is one of the most common side effects of cancer and its treatment.
- Conditions
- Gastric Cancer, Surgical Wound Infection, Fatigue, Quality of Life
- Trial name
- NCT03766945
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Wound Healing Disorder, Post-Surgical Complication
NovoX®Cup as Primary Dressing After Breast Reduction
Breast reduction is one of the most frequently performed plastic surgeries. Studies have shown that breast reduction surgery significantly improves the patients' suffering and leads to a better health-related quality of…
- Conditions
- Wound Healing Disorder, Post-Surgical Complication, Mammaplasty
- Trial name
- NCT06420323
- Testing
- Treatment with NovoX® Cup, Treatment with Omnistrip®
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- MOSS S.p.A.
Rupture, Venous Thromboembolism
Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture
This prospective randomized study aims to determine whether intermittent pneumatic compression (IPC), 75 patients, beneath functional bracing compared to treatment-as-usual in plaster cast, 75 patients, can reduce the Venous…
- Conditions
- Rupture, Venous Thromboembolism, Venous Thrombosis, Surgical Wound Infection
- Trial name
- NCT01317160
- Testing
- Intermittent pneumatic compression (IPC)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Surgical Site Infection
The Inselspital Surgical Cohort Study
Personalizing surgical care is of enormous clinical relevance, when considering the number of patients undergoing surgery in Switzerland every year.
- Trial name
- InSurg (NCT04096885)
- Testing
- Blood and urine samples, skin and stool swabs
- Where
- Switzerland
- Volunteers
- 1,226 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Wound of Skin, Wound Heal
Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting
The aim of this study is to compare negative pressure wound therapy to traditional care after split-thickness skin grafting in patients aged over 18.
- Conditions
- Wound of Skin, Wound Heal, Wound, Wound Open
- Trial name
- TRUTH (NCT03649308)
- Testing
- Negative Pressure Wound Therapy, Conventional treatment
- Where
- 2 sites in Finland
- Volunteers
- 160 people
- Sponsor
- Central Finland Hospital District
Surgical Site Infection (SSI), Mediastinitis
Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy
The goal of this clinical trial is to learn whether applying autologous platelet-rich plasma (PRP) to the sternal wound during heart surgery improves wound healing and reduces complications after surgery.
- Conditions
- Surgical Site Infection (SSI), Mediastinitis, Delayed Wound Healing
- Trial name
- NCT07352020
- Testing
- Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Scar
Botox in the Healing of Surgical Wounds of the Neck
The investigators hypothesize that Botox A will reduce scarring and improve healing of surgical neck wounds.
- Trial name
- NCT01177358
- Testing
- Botulinum Toxin Type A, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Cataract, Astigmatism
Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration (ARCUATAS)
This is an observational, prospective follow-up post-marketing study of CE marked medical devices aimed at treating astigmatism in patients with cataracts.
- Trial name
- ARCUATAS (NCT05053620)
- Testing
- Calculation of the arcuate intrasomal incisions
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Adult Patients Undergoing Open Heart Replacement of the Aortic Valve for Aortic Stenosis or Insufficiency
Elimination of CO2-insufflation-induced Hypercarbia in Open Heart Surgery
The study aim was to evaluate if an additional separate venous reservoir eliminates CO2-insufflation induced hypercapnia and keeps sweep gas flow of the oxygenator constant during open heart surgery.
- Trial name
- NCT04202575
- Testing
- Tube clamping
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska University Hospital
Colorectal Resection
Impact of Triclosan-coated Suture on Surgical Site Infection After Colorectal Surgery
Despite adequate antimicrobial prophylaxis and perioperative correction of risk factors, surgical site infections (SSI) remain the most frequent complication of colorectal resection (range 10-17%).
- Trial name
- NCT01869257
- Testing
- Triclosan coated suture, regular suture
- Where
- Italy
- Volunteers
- 279 people
- Sponsor
- University of Milano Bicocca
Wound Infection
Prevena™ vs Dermabond in Groin Wound Infections in Vascular Surgery
This study evaluates the clinical efficacy and cost effectiveness of Prevena Incision Management System versus Dermabond in preventing groin wound infections in patients who undergo vascular surgery requiring a groin wound.
- Trial name
- NCT02836990
- Testing
- Prevena Incision Management System, Dermabond
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- State University of New York at Buffalo
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