Clinical trials: Incisions, Surgical
Surgical Incision, Nose Deformity
Rhinoplasty Scar Comparison
Traditional suture closure of the columellar scar in rhinoplasty is achieved with permanent skin sutures. These sutures create less inflammation and are thought to lead to improved final scar outcomes.
- Trial name
- NCT03748459
- Testing
- Closure with Permanent Suture, Closure with Resorbable Suture
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Surgical Wound Infection
Clorhexidine Versus Povidone for the Prevention of Surgical Site Infection After Cesarean Section
Many solutions are used for cleaning the skin of a patient previous to a surgery. Although the efficacy of clorhexidine has been proved in other surgical procedures, there is only a retrospective study in cesarean section (they…
- Trial name
- NCT01741649
- Testing
- Clorhexidine, Povidone
- Where
- Panama
- Volunteers
- 800 people
- Sponsor
- Saint Thomas Hospital, Panama
Wound Complication, Surgical Wound Infection
Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions
This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without…
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain, Postoperative Complications
- Trial name
- SCPPB (NCT06191159)
- Testing
- Scalpel and standard electrocautery or PEAK PlasmaBlade, PEAK PlasmaBlade, Standard Electrocautery
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of British Columbia
Wound
Evaluation of the Safety and Effectiveness of ALLEVYN Gentle Border
The clinical study will evaluate the safety and effectiveness of the ALLEVYN Gentle Border. The study is a post-market clinical follow-up to assess clinical performance and safety of ALLEVYN Gentle Border with new wound contact…
- Trial name
- NCT03877484
- Testing
- ALLEVYN Gentle border
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 43 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Ventral Incisional Hernia
Gentrix™ Versus Biological or Prosthetic Mesh
The hypothesis for this study is complex incisional hernia repair using the separation of components technique reinforced with retrorectus placement of Gentrix™ Surgical Matrix will lead to fewer incisional hernia recurrences and…
- Trial name
- NCT03034213
- Testing
- Gentrix™ Surgical Matrix (Treatment), Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of South Florida
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Colorectal Cancer, Surgical Site Infection
Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery
The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery.
- Conditions
- Colorectal Cancer, Surgical Site Infection, Chlorhexidine, Complications
- Trial name
- NCT06869096
- Testing
- Intraoperative area irrigation
- Where
- China
- Volunteers
- 532 people
- Sponsor
- Nanchong Central Hospital
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-II)
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if PDT has an effect on bacterial skin colonization in order to improve skin antisepsis…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- NCT04618276
- Testing
- Photodynamic Therapy
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Surgical Wound Infection
Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial
This is a prospective, randomized control trial evaluating the efficacy of iodophor-impregnated adhesive drapes for reducing bacterial count in hip surgery.
- Trial name
- NCT02919410
- Testing
- iodophor-impregnated adhesive drapes, No adhesive drapes
- Sponsor
- Rothman Institute Orthopaedics
Infection Prosthesis Hip and Knee, Infection, Prosthesis Related
Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen.
The goal of this randomized control trial is to investigate the superiority of 5 days (extended) versus a single dose of cefazolin prophylaxis in revision arthroplasty of the hip and knee.
- Conditions
- Infection Prosthesis Hip and Knee, Infection, Prosthesis Related, Joint Infection, Infection, Surgical Site
- Trial name
- REViSION (NCT06402591)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 751 people
- Sponsor
- Radboud University Medical Center
Surgery, Surgical Injury
Mini-invasive Approaches to Aortic Surgery
There are many different types of mini-invasive approaches to aortic surgery. Ministernotomy and anterior right minithoracotomy are the two main techniques applied for minimally invasive aortic valve replacement, but if one of…
- Conditions
- Surgery, Surgical Injury, Surgical Procedure, Unspecified, Surgical Incision
- Trial name
- MSvsMT (NCT04350697)
- Testing
- Aortic Surgery
- Where
- Italy
- Volunteers
- 2,425 people
- Sponsor
- University of Florence
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng
Staphylococcal Infections, Surgical Site Infection
Effect of Exeporfinium Chloride (XF-73) Gel on Nasal S.Aureus in Patients at Risk of Post-op Staphylococcal Infection
This study looks at the difference between XF-73 and placebo in reducing the carriage of a bacteria S. aureus in the nose before, during and after heart surgery.
- Trial name
- NCT03915470
- Testing
- XF-73
- Where
- 21 sites in United States, Georgia and 1 more
- Volunteers
- 124 people
- Sponsor
- Destiny Pharma Plc
Laparoscopic Surgery
Clinical Trial of MedLogic LiquiBand Laparoscopic Versus Dermabond in the Closure of Surgical Incisions
To evaluate the effectiveness, safety, and utility of LiquiBand Laparoscopic™ in relation to a currently approved active control product (High Viscosity DermaBond).
- Trial name
- NCT00762905
- Testing
- LiquiBand Laparoscopic, Dermabond
- Where
- 4 sites in United Kingdom
- Volunteers
- 460 people
- Sponsor
- MedLogic Global Limited
Surgical Wound
Reconstruction Flaps for Nasal Surgical Wounds RCT
The purpose of this study is to determine whether there is a significant difference in aesthetic and functional outcomes between nasalis sling flaps and lobed flaps of nasal tip wounds requiring reconstruction.
- Trial name
- NCT04729231
- Testing
- Nasalis Sling Flap, Lobed Transposition Flap
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Colorectal Surgery
Mechanical Bowel Prep Randomized Study
Following colon surgery, surgical site infection (SSI) is the most common complication and leads to longer recovery time for patients and increased health care costs.
- Trial name
- NCT04931173
- Testing
- IVA+OA versus IVA+MBP+OA
- Volunteers
- 1,062 people
- Sponsor
- Mount Sinai Hospital, Canada
Colorectal Neoplasms, Diverticulitis
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery.
- Conditions
- Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
- Trial name
- NCT03042091
- Testing
- Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Thomas Jefferson University
Surgical Site Infection
Efficacy Study of Delayed Primary Closure to Reduce Rate of Wound Infection in Complicated Appendicitis
Research hypothesis: Does delayed primary wound closure after appendectomy in adults with complicated appendicitis reduce postoperative superficial surgical site infection compare to primary wound closure.
- Trial name
- NCT01659983
- Testing
- Primary wound closure
- Where
- 7 sites in Thailand
- Volunteers
- 600 people
- Sponsor
- Ramathibodi Hospital
Infection of Total Knee Joint Prosthesis
Evaluating Bactisure Wound Lavage in Orthopedic Wounds
To demonstrate a reduction of debris in knee synovial fluid as demonstrated by WBC cell counts before and after irrigation with Bactisure Wound Lavage.
- Trial name
- NCT03192124
- Testing
- Bactisure
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Zimmer Biomet
Surgical Site Infection
Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study
This multicentre, adaptive, pragmatic, double-blind, three-arm, placebo-controlled, randomised, non-inferiority clinical trial will compare the incidence of surgical site infection and other healthcare associated infections…
- Trial name
- CALIPSO (NCT05447559)
- Testing
- Cefazolin, Water for injection
- Where
- 27 sites in United States, Australia and 3 more
- Volunteers
- 9,180 people
- Sponsor
- Monash University
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