Clinical trials: Incisions, Surgical
Liver Transplant Infection, Surgical Site Infection
Pharmacological Study of Cefazolin Antibioprophylaxis in Liver Transplantation
This study describes Cefazolin pharmacokinetics variation to target levels during liver transplantation.
- Conditions
- Liver Transplant Infection, Surgical Site Infection, Antibiotic Prophylaxis, Cephazolin Adverse Reaction
- Trial name
- ProCeTH (NCT04280237)
- Testing
- Blood samples
- Where
- France
- Sponsor
- University Hospital, Tours
Surgical Site Infections
PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
To study the effect of applying a PHMB-based antiseptic solution to tie-over dressings in full-thickness surgical wounds in dermatologic surgery in order to minimise the development of surgical site infections.
- Trial name
- NCT02253069
- Testing
- Applying Prontosan antiseptic solution to tie-over dressings
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Pain, Surgical Wound
Preemptive Paracetamol for Postoperative Pain
The purpose of this study is to test whether a dose of paracetamol given before surgical incision is more effective at reducing postoperative pain and analgesic consumption in cervical spine surgery versus a dose given at the end…
- Trial name
- PPPP (NCT02425254)
- Testing
- Intravenous paracetamol, Intravenous saline 0.9%
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Surgical Site Infections
Examination of the Effect of Skin Antisepsis With Pre-heated Povidone Iodine on Surgical Site Infections: A Quasi-Experimental Study
Surgical Site Infections (SSI) develop as a complication of surgical care 30-90 days after surgery without implants and within 1 year after implanted operations.
- Trial name
- NCT04969302
- Testing
- Follow-up
- Where
- Cyprus
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Urethral Stricture
A Comparative Study of the Antibacterial Effects of Two Preoperative Hair Removal Methods in Male Patients With Urethral Stricture
Male urethral stricture is one of the common diseases in urology, with risk factors including a history of hypospadias surgery, indwelling urinary catheterization or instrumental manipulation, trauma, transurethral surgery, and…
- Trial name
- NCT07508566
- Testing
- Wiping with wet wipes containing 2% chlorhexidine gluconate (CHG).
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Wound Heal, Wound Surgical
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part II
The purpose of the present study is to evaluate the influence of the post-surgical chlorhexidine indication in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the…
- Conditions
- Wound Heal, Wound Surgical, Oral Soft Tissue Conditions, Chlorhexidine Adverse Reaction
- Trial name
- NCT04276129
- Testing
- periodontal surgery + 24 hr buccal attached gingiva (G) biopsy, post-surgical CHX mouth-rinses indication
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- University of Roma La Sapienza
Pilonidal Sinus, Surgical Wound
Ghnnam Excision Technique for Pilonidal Sinus
Pilonidal disease is a common disorder of the sacrococcygeal region. It comprises a variety of problems, including infection/abscess and the development of a chronic sinus cavity.here we try a minimmally invasive method for…
- Conditions
- Pilonidal Sinus, Surgical Wound, Dressing by Cyanoacrylate
- Trial name
- NCT01399320
- Testing
- cyanoacrylate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Incisional Hernia, Incision Infection
Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections
In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate…) provides a remarkable…
- Trial name
- NCT04394988
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Surgical Wound, Post Operative Wound Infection
Early Versus Delayed Bathing of Orthopaedic Surgical Wounds
This is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures.
- Trial name
- EVDB (NCT06014411)
- Testing
- Time to bathing (delayed), Time to bathing (early)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Wound Infection, Postoperative Complications
Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study)
This is a prospective randomized, controlled, unblinded, interventional feasibility study to evaluate if showering with post operative drains in place leads to an increase in complications.
- Conditions
- Postoperative Wound Infection, Postoperative Complications, Surgical Site Infection, Drain Site Complication
- Trial name
- SHOWER (NCT04725916)
- Testing
- Showering, Restriction of Showering
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sean Devitt
All Diseases That Require Gastrointestinal Open Surgery
Subcutaneous Closed-Suction Drainage Affects Surgical Wounds Healing in Lower Gastrointestinal Open Surgery: a Randomized Controlled Study
This is a single-center, randomized controlled trial to evaluate whether subcutaneous closed-suction drainage would decrease the incidence of poor surgical site healing in lower gastrointestinal open surgery.
- Trial name
- NCT05318430
- Testing
- Subcutaneous closed-suction drainage device
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Friendship Hospital
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery
This study is being done to find out if the height of the fluid bag and the direction of the surgical cut affect the pressure of the fluid used during unilateral biportal endoscopic (UBE) spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Degenerative Disease
- Trial name
- NCT07837427
- Testing
- Unilateral Biportal Endoscopic Surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fan Zhang
Inguinal Incisions
Interest of 2-octyl-cyanoacrylate (Dermabond®) in Closing Surgical Incisions in Children Before Acquisition of Continence
Inguinal incisions are the most frequent incisions used in children before the acquisition of continence (180 incisions per year for the Pediatric Surgery Department in Nice CHU).
- Trial name
- NCT00909805
- Testing
- cutaneous suture (Surjet), 2-octyl-cyanoacrylate (Dermabond® glue)
- Where
- 4 sites in France
- Volunteers
- 89 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs)
Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care
This clinical study is being conducted to evaluate how well the Miro3D Wound Matrix helps heal difficult wounds and ulcerations in an outpatient care setting.
- Conditions
- Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD)
- Trial name
- NCT06939673
- Testing
- Acellular Porcine-Derived Wound Matrix
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Reprise Biomedical, Inc.
Wound Infection, Wound Surgical
Efficacy of Negative Pressure Wound Closure Therapy by PICO System in Prevention of Complications of Femoral Artery Exposure
Evaluate negative pressure wound closure therapy by PICO system in Prevention of complications of femoral artery exposure.
- Trial name
- NCT04453319
- Testing
- Femoral Wound Closure and dressing
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Incisional Hernia
Incisional Hernia Outcomes Study Using Parietex Composite Mesh
The purpose of this study is to describe the outcomes of laparoscopic incisional hernia repair surgery and to record the outcomes of patients after surgery.
- Trial name
- NCT00459602
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Columbia University
Surgical Wound Dehiscence, Wound Infection
Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy
Wound complications after Cesarean section (C-section) are common in obese women. Approximately 25% of obese women having a C-section will have a wound complication.
- Trial name
- NCT00654641
- Testing
- Negative pressure wound closure, Standard wound closure
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- West Virginia University
Surgical Site Infections, Post Operative Complication
2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients
Surgical site infection (SSI) following spinal surgery is a frequent complication and results in higher morbidity, mortality and healthcare costs.
- Trial name
- DeSSI (NCT02490631)
- Testing
- 2% chlorhexidine gluconate cloths
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Vanderbilt University
Healing Surgical Wounds
Comparative Evaluation of Osseous Resection by Piezoelectric Device Versus Conventional Rotary Instruments
The aim of this study is to comparatively evaluate changes in periodontal healing, surgical time required and postoperative morbidity observed in patients undergoing osseous resection in crown lengthening procedure with…
- Trial name
- NCT03916653
- Testing
- osseous resection using piezoelectric device in surgical crown lengthening, Osseous resection using conventional rotary instruments in surgical crown lengthening
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Recurrent Hernia
Review of Complex Recurrent Hernia Repair
Abdominal wall incisional hernia is a common finding in patients who have undergone previous intra-abdominal surgeries. Common methods of abdominal fascial closure include primary closure, mesh inlay versus onlay, with or without…
- Trial name
- BARS (NCT01644695)
- Testing
- Bony Anchoring Reinforcement System
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Institute For Advanced Reconstruction
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