Clinical trials: Incisions, Surgical
SURGICAL SITE INFECTION
Early Short-term Antibiotic Therapy in Penetrating Abdominal Trauma, 3 vs 7 Days
Abdominal penetrating trauma represents a frequent cause of consult into emergency rooms in Venezuela. Accidents and violence at Hospital "Miguel Perez Carreño" along april 2009 were represented by gunshots and stabbing wounds…
- Trial name
- NCT01203046
- Testing
- Ertapenem
- Volunteers
- 56 people
- Sponsor
- Silvia M. Pinango L.
Curative Breast Cancer Surgery, Inflammatory Positive/Negative Status
Ketorolac in Breast Cancer Surgery
Do the use of Ketorolac in one intravenous injection at the moment of the operative incision reduce the number of recurrence in patient with advanced breast cancer without inflammation signs.
- Conditions
- Curative Breast Cancer Surgery, Inflammatory Positive/Negative Status, Pre Surgical Incision Administration
- Trial name
- KBCt (NCT01806259)
- Testing
- Ketorolac 30 mg IV
- Where
- Belgium
- Volunteers
- 203 people
- Sponsor
- Université Catholique de Louvain
Incisional Hernia, Surgical Wound Infection
Prophylactic Negative Pressure Wound Therapy for Patients Undergoing Incisional Hernia Repair
The study will examine the effect of using Negative Pressure Wound Therapy (NPWT) compared with standard wound dressing among patients undergoing elective open surgery for incisional hernia.
- Conditions
- Incisional Hernia, Surgical Wound Infection, Surgical Site Infection, Quality of Life
- Trial name
- PROPRESS (NCT05050786)
- Testing
- Negative Wound Pressure Therapy (Prevena(TM)), Standard Wound Dressing
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Kristian Kiim Jensen
Surgical Incision
A Comparison Between Two Post-operative Dressings
Surgical site infections are one of the leading causes of post-operative morbidity and mortality worldwide. The ideal post-operative dressing is impermeable and remains intact preventing contamination of the incision with…
- Trial name
- DrySee (NCT04888624)
- Testing
- DrySee® dressing with moisture detection, Tegaderm® + Pad transparent film dressing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SerenaGroup, Inc.
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Goiter, Thyroid Neoplasms
Subcuticular Suture Versus Synthetic Glue in Thyroidectomy Incision
The aim of this study is to compare aesthetic results of two different type of sutures (subcuticular versus synthetic glue) in post-thyroidectomy incisions.
- Conditions
- Goiter, Thyroid Neoplasms, Parathyroid Pathologies
- Trial name
- SCSvsSG (NCT00754182)
- Testing
- Octylcyanoacrylate (Dermabond), Subcuticular reabsorbable suture (Caprosyn)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Hyperoxia, Postoperative Complication
Individualized Perioperative Open-lung Ventilatory Strategy With High Versus Conventional Inspiratory Oxygen Fraction (iPROVE-O2).
The iPROVE-O2 trial aims at comparing the efficacy of high and conventional FiO2 within a perioperative individualized ventilatory strategy to reduce the overall incidence of SSI.
- Conditions
- Hyperoxia, Postoperative Complication, Surgical Site Infection
- Trial name
- iPROVE-O2 (NCT02776046)
- Testing
- High FiO2, Conventional FiO2
- Where
- Spain
- Volunteers
- 756 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Surgical Site Infection
Surgical Site Infection After Episiotomy Repair Related to Routine Use of Antibiotic Prophylaxis in Low-Risk Population
Bacterial infections occurring during labor, childbirth, and the puerperium may be associated with considerable maternal and perinatal morbidity and mortality.
- Trial name
- NCT06154720
- Testing
- Antibiotics
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fracture Femur, Fracture Tibia
Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail
Long-bone fractures, particularly of femur and tibia, are common following fall injury and road traffic accidents.1,2 The standard treatment is "intramedullary nailing," where a metal rod is inserted into the center of the bone…
- Conditions
- Fracture Femur, Fracture Tibia, Surgical Site Infection (SSI), Antibiotic
- Trial name
- NCT07554079
- Testing
- Short Course Antibiotics, Standard Course Antibiotics
- Where
- Nepal
- Volunteers
- 56 people
- Sponsor
- Kathmandu University School of Medical Sciences
Wound Complication
Tissue Reinforcement of Incisional Closure Among High Risk Patients
Half of all individuals will undergo abdominal surgery in their lifetime. Following abdominal surgery, 30% of patients will suffer a major chronic complication with their wound closure in the first post-operative year.
- Trial name
- NCT03148496
- Testing
- Biologic Mesh, Small Bites, Large Bites
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- The University of Texas Health Science Center, Houston
Surgery, Surgical Site Infection
SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty
Comparing the growth of intra-operative tissue cultures of Cutibacterium Acnes after primary shoulder replacement when using a no-prep control group versus antimicrobial wound gel versus betadine applied to the skin layer after…
- Conditions
- Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
- Trial name
- NCT05919888
- Testing
- Povidone-Iodine, SURGX Wound Gel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Infections, Surgery
Study Looking at the Effect of Silverlon on Post Operative Wound Infections
This clinical study is a prospective, randomized, controlled trial of patients undergoing elective colorectal surgical procedures that receive an abdominal skin incision of at least 6 cm.
- Trial name
- NCT01143883
- Testing
- Silverlon, Standard of Care Dressing
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Jorge Marcet
Surgical Site Infection, Pancreaticoduodenectomy
Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy
Preoperative biliary drainage predisposes the bile to be contaminated with bacteria of the duodenum. These bacteria colonizing the bile are a potential source for surgical site infections after pancreaticoduodenectomy and many…
- Conditions
- Surgical Site Infection, Pancreaticoduodenectomy, Biliary Tract Infection Bacterial
- Trial name
- NCT05581017
- Testing
- Preoperative biliary drainage
- Where
- Finland
- Volunteers
- 376 people
- Sponsor
- Helsinki University Central Hospital
Colostomy Stoma, Ileostomy - Stoma
Needle-Aspirated Compression Dressing Following Ostomy Reversal
Negative pressure wound dressings have been studied and shown to have applications in decreasing rates of surgical wound infections.
- Conditions
- Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
- Trial name
- NCT03703661
- Testing
- Needle-Aspirated Negative Pressure Dressing, Control
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Nephrectomy, Partial Nephrectomy
Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.
Using a randomized double-blinded study design, the study goal is to evaluate the superiority of Erector Spinae Plane block (ESPB) in the peri-operative pain management of patients undergoing surgery through a flank or anterior…
- Conditions
- Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
- Trial name
- NCT03691935
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Skin Diseases, Surgical Site Infection
Surgical Hand Antisepsis With Propan-ol-1 60% Per Rubbing and Scrubbing
The present study evaluates the effects of to compare bactericidal efficacy using the reference antiseptic product propan-ol-1 60% using the hand rub method versus hand scrub method in order to test if pass the standard european…
- Trial name
- NCT04446923
- Testing
- Hand antisepsis by scrub
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Total Knee Replacement Surgery
Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
This study evaluates the effect of Iodine-impregnated self-adhesive plastic drapes (IIAD) on the quantity of skin bacteria, which is a known factor in the development of surgical site infections in orthopedic surgery.
- Trial name
- NCT02342561
- Testing
- Ioban 2 incision drape, 3M
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Vancomycin, Implantable Neural Stimulator
Intrawound Vancomycin Prophylaxis for Neural Stimulator
The implantable pulse generator (IPG) is a device that generates electrical current to stimulate the spine, heart, or brain for various chronic conditions.
- Conditions
- Vancomycin, Implantable Neural Stimulator, Deep Brain Stimulation, Surgical Site Infection
- Trial name
- IV-DIRT (NCT03221023)
- Testing
- Vancomycin Hydrochloride, Saline Solution
- Where
- Canada
- Volunteers
- 900 people
- Sponsor
- University of British Columbia
Colorectal Surgery, Surgical Wound Infection
A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection
The purpose of this study is to determine whether the gentamicin-collagen sponge is safe and effective for preventing surgical wound infections in patients undergoing colorectal surgery.
- Trial name
- NCT00600925
- Testing
- gentamicin-collagen sponge dipped in saline
- Where
- 39 sites in United States
- Volunteers
- 602 people
- Sponsor
- Innocoll
Healing Wound, Iron-deficiency
Impact of Iron Stores on Wound Healing in Plastic Surgery
In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight.
- Conditions
- Healing Wound, Iron-deficiency, Surgical Wound
- Trial name
- IRONPLAST (NCT04276168)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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