Clinical trials: Incisions, Surgical
Keratoconus, Corneal Dystrophies
Laser Assisted Procedures in Penetrating Keratoplasty
Laser- assisted procedures in penetrating keratoplasty (PK) are proposed to improve the surgical outcomes: minimally invasive procedures, improved biomechanical stability of the transplanted flap, reduction of rejection risks…
- Conditions
- Keratoconus, Corneal Dystrophies, Corneal Opacity
- Trial name
- NCT02173847
- Testing
- Penetrating keratoplasty, Femtosecond laser, Diode laser
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Ospedale Santo Stefano
Surgical Site Infection, Colorectal Cancer
Comparison of Method for Skin Closure in Colorectal Cancer.
Compared to tissue adhesives and skin stapling devices, tissue adhesives are reported to have advantages in terms of wound infection and cost competitiveness.
- Trial name
- NCT06549803
- Testing
- skin bond, skin stapler
- Where
- South Korea
- Volunteers
- 304 people
- Sponsor
- Yoon Suk Lee
Surgical Site Infection
INtestinal Dysbiosis and TRanslocation of Bacteria in Patients Undergoing Surgery
The goal of this observational study is to contribute to a better understanding of the perioperative kinetics of intestinal microbial composition and association with surgical site infections.
- Trial name
- INTRA (NCT05775341)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Wound Infection
A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery
Following closure of surgical incisions, wounds may develop redness, swelling, and drainage which may result in increased pain and infection.
- Trial name
- NCT00576745
- Testing
- Vicryl Suture, 3M TM S Surgical Skin Closure System
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- American Heart Association
Postoperative Pain, Single-incision Thoracoscopic Surgery
Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery
This is a single center, randomized, single blind study to compare the analgesic effect of different anesthesia and postoperative analgesic methods in uniportal VATS lung surgery.
- Trial name
- CDAAMIUVLS (NCT03311737)
- Testing
- general anesthesia, epidural anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Wound Closure Technique, Wound Dehiscence, Surgical
Comparison of Cosmetic Outcome and Patient Satisfaction Between Staples and Suture Technique for Wound Closure Following Upper Limb Surgeries
Surgical wound closure is an essential component of postoperative care that influences wound healing, infection rates, cosmetic appearance, and patient satisfaction.
- Trial name
- NCT07633977
- Testing
- Staples, Sutures
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- Kathmandu University School of Medical Sciences
Diabetes, Hyperglycemia
The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery
The purpose of this study was to investigate the effects of three different glycemic treatment conditions (tight, conventional, and standard) in the intraoperative period on: 1) postoperative surgical site infections, and 2)…
- Conditions
- Diabetes, Hyperglycemia, Surgical Site Infection
- Trial name
- NCT01831154
- Testing
- Tight Glycemic, Conventional Glycemic, Standard Glycemic
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- James A. Haley Veterans Administration Hospital
Infection Due to Coronary Artery Bypass Graft (Diagnosis)
Surgical Wound Infection Prevention Bundle in Patients Undergoing Coronary Bypass Graft Surgery
estimate the utilization of locally customized surgical wound infection bundle to prevent and or control of infection in patients undergoing CABG surgery in Sohag
- Trial name
- NCT07003750
- Testing
- Surgical wound infection prevention bundle
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Corneal Toxicity, Ototoxicity
A Comparison of Infection Rates Between Two Surgical Sites
Does the use of chlorhexidine scrub prior to cutaneous surgery on the face increase the chances of toxicity to the eyes or ears? In addition, does the us eof chlorhexidine scrub on the face prior to cutaneous surgery decrease the…
- Conditions
- Corneal Toxicity, Ototoxicity, Surgical Site Infection
- Trial name
- NCT01263262
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Surgical Infection
Routine Preoperative Antibiotic Prophylaxis in Modified Radical Mastectomy
This is a randomized, double blinded, placebo-controlled trial on the routine use of preoperative antibiotic prophylaxis in modified radical mastectomy to evaluate the efficacy of preoperative prophylactic antibiotics in the…
- Trial name
- NCT01558986
- Testing
- Cefazolin, Sterile water
- Where
- Philippines
- Volunteers
- 254 people
- Sponsor
- University of the Philippines
Surgical Wound, Wound Healing Delayed
Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review
The goal of this clinical trial is to learn if artificial intelligence within digital wound monitoring of surgical wounds can prioritise non-healing wounds for urgent review in patients having first/redo CABG surgeries with or…
- Conditions
- Surgical Wound, Wound Healing Delayed, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- WISDOM (NCT06475703)
- Testing
- Isla wound prioritisation module, Standard follow-up
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Colorectal Surgery
Safety and Efficacy of One Dose Prophylactic Antibiotic in Laparoscopic Colorectal Surgery
In colorectal surgery, the use of prophylactic antibiotics is recommended. The standard use of antibiotics for colorectal surgery is three doses.
- Trial name
- NCT01220661
- Testing
- Cefotetan
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- National Cancer Center, Korea
Liver Tumors
The Efficacy of Chlorhexidine Gluconate Pre - Disinfection Scrubbing in Preventing Surgical Site Infections for Hepatectomy Patients
To test whether pre - disinfection skin scrub with 4% chlorhexidine gluconate is more effective on the reduction of surgical site microbial colonization and subsequent infection than is normal saline.
- Trial name
- NCT01782573
- Testing
- Chlorhexidine gluconate, 0.9% Sodium Chloride
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Changhua Christian Hospital
Hematoma, Surgical Wound
Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.
The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery.
- Conditions
- Hematoma, Surgical Wound, Surgery, Eye Bruise
- Trial name
- NCT03917641
- Testing
- Khat leaves
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Surgical Site Infection
Effect of Preoperative Diet on Perioperative Gut Microbiome
The aim of the study is to evaluate the gut microbiome (i.e. bacteria, viruses, and fungi that reside in the gut) of people undergoing abdominal surgery, evaluate whether specific diets can change the gut microbiome, and, if so…
- Trial name
- NCT05027763
- Testing
- high-fiber, fermented
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Infection, Surgery
Topical Vancomycin for Neurosurgery Wound Prophylaxis
This study is a collaboration between New York Presbyterian (NYP)-Columbia and NYP-Cornell that seeks to evaluate the use of topical vancomycin and its reduction on surgical site infection (SSI) in neurosurgical procedures.
- Conditions
- Infection, Surgery, Nervous System Diseases
- Trial name
- Vanguard (NCT02284126)
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 1,103 people
- Sponsor
- Columbia University
Surgical Site Infection
Prophylactic Antibiotics After Cesarean
The purpose of this study is to determine if the addition of a 48-hour course of post-operative antibiotics to the recommended course of pre-operative antibiotics improves surgical site infection rate in patients who are obese…
- Trial name
- PACT (NCT03187106)
- Testing
- Cephalexin, Metronidazole
- Where
- 2 sites in United States
- Volunteers
- 321 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Dehiscence, Surgical Wound
Evaluation of Safety and Efficacy of Using Seraffix LTB - (Laser Tissue Bonding) System
The purpose of this study is to evaluate the safety and effectiveness of using Seraffix LTB system for soft tissue bonding.
- Trial name
- NCT00521755
- Testing
- Seraffix LTB
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Seraffix
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