Clinical trials: Incisions, Surgical
Surgical Site Infection
Skin Staples vs Polypropylene in Elective Laparotomy
Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07781878
- Testing
- Skin staples, Polypropylene skin suture
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Radius Fracture Distal, Surgery
Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up
A 10-year follow up of a fusion of two earlier published randomized controlled trials. 203 patients with displaced distal radius fractures were randomized to surgery with a volar locking plate or external fixation.
- Conditions
- Radius Fracture Distal, Surgery, Surgery--Complications, Treatment Complication
- Trial name
- EXTEND (NCT05371938)
- Testing
- Volar locking plate, external fixation
- Where
- Sweden
- Volunteers
- 203 people
- Sponsor
- Olof Skoldenberg
Cornea, Astigmatism
Multifocal-toric IOL Compared to Multifocal IOL Combined With Limbal Relaxing Incisions for Correction of Moderate Astigmatism During Cataract Surgery
The purpose of the present study is to compare the outcome of multifocal toric intraocular lens with standard multifocal lens plus incisional surgery in patients undergoing bilateral cataract surgery.
- Conditions
- Cornea, Astigmatism, Cataract
- Trial name
- NCT06277349
- Testing
- Toric multifocal IOL, Non-toric multifocal IOL
- Volunteers
- 30 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Hip Dysplasia
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1.
- Trial name
- PILA PAO (NCT06519955)
- Testing
- Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Michael C Willey
Dural Defect, Cerebrospinal Fluid Leak
Immiseal™ Dural Sealant Post-Market Registry Study
This is a multicentre, prospective, open-label, single-arm, observational, post-market clinical follow-up registry study designed to observe the safety and performance of the Immiseal™ Dural Sealant System when used as an adjunct…
- Conditions
- Dural Defect, Cerebrospinal Fluid Leak, Neurosurgical Procedures
- Trial name
- NCT07651826
- Where
- Latvia
- Volunteers
- 85 people
- Sponsor
- Medprin Regenerative Medical Technologies Co., Ltd.
Periimplantitis, Dental Plaque
Antimicrobial Activity of Two Mouthwashes
This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.
- Conditions
- Periimplantitis, Dental Plaque, Periodontal Diseases, Caries
- Trial name
- NCT02375178
- Testing
- chlorhexidine, Polyhexamethylene biguanide, Sterile saline solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Children with neuromuscular disorders such as cerebral palsy, children with kyphosis and post-traumatic scoliosis have higher infection rates after scoliosis surgery than healthy children who undergo scoliosis surgery.
- Trial name
- NPWT (NCT02790385)
- Testing
- Negative Pressure Wound Therapy, Standard Gauze Treatment
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dehiscence, Surgical Wound
Evaluation of Safety and Efficacy of Using Seraffix LTB - System for Excisional Biopsy Wounds Closure
The purpose of this study is to evaluate the safety and effectiveness of using Seraffix LTB system for excisional biopsy wounds closure
- Trial name
- NCT00525434
- Testing
- Seraffix LTB
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Seraffix
Postoperative Complications, Hernia
Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?
The purpose of this study is to determine whether drainage after prosthetic repair of incisional abdominal hernias increases or decreases complications such as infection, seromas and hematomas.
- Trial name
- NCT00478348
- Testing
- Prosthetic repair of abdominal incisional hernia
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Lausanne Hospitals
Surgical Site Infection
Antibiotics for Prevention of SSI in Obese Women Undergoing CS
Effect of cephalexin plus metronidazole on SSI better than cephalexin alone in obese women undergoing CS
- Trial name
- NCT03736187
- Testing
- Cephalexin
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Incision
BandGrip® Closure of Surgical Incisions Following Arthroscopic Surgery
A single-arm, prospective, unblinded, post marketing, single center study using BandGrip to close incisions post arthroscopic shoulder surgery.
- Trial name
- NCT03644316
- Testing
- BandGrip skin closure device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- BandGrip
Surgical Site Infection
Cheetah - Sterile Glove and Clean Instrument Change at the Time of Wound Closure to Reduce Surgical Site Infection
To assess whether the practice of using separate sterile gloves and instruments to close wounds at the end of surgery compared to current routine hospital practice can reduce surgical site infection
- Trial name
- Cheetah (NCT03980652)
- Testing
- Change of gloves and sterile instruments
- Volunteers
- 12,800 people
- Sponsor
- University of Birmingham
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Superficial Abscess Packing
Abscess Packing Versus Wick Placement After Incision and Drainage
Abscesses or "boils" are becoming more common every year and are a common reason children come to the Emergency Department. For the abscess to heal the skin needs to be opened to let the pus come out.
- Trial name
- NCT01281930
- Testing
- Full packing into abscess cavity, Wick placement into abscess cavity
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Washington University School of Medicine
Surgical Site Infection
DFA-02 in Patients Undergoing Colorectal Surgery
This is a randomized, double-blind, placebo controlled, safety, tolerability, and pharmacokinetic dose escalation Phase II study of DFA-02 in patients undergoing colorectal surgery to evaluate the safety, tolerability and…
- Trial name
- NCT01496352
- Testing
- DFA-02
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Postoperative Hernia
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR)
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Trial name
- (PROTOP-PAR) (NCT05508152)
- Testing
- Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital de Granollers
Skin Cancer Face, Quality of Life
Buddy Relationships in DermatoloGic Excisions for Skin Cancer
More than 5 million skin cancer surgeries are performed each year in the United States with 80% of tumors appearing on the head and neck.
- Conditions
- Skin Cancer Face, Quality of Life, Surgical Wound, Peer Mentorship
- Trial name
- BRIDGES (NCT04036344)
- Testing
- Peer Mentorship Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cataract, Phacoemulsification
Comparison of Manual Super Small Incision Cataract Surgery and Phacoemulsification
The purpose of this study is to compare the safety and efficacy of manual super small incision cataract surgery (MSSICS) and Phacoemulsification.
- Trial name
- NCT01146964
- Testing
- MSSICS, Phacoemulsification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
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