Clinical trials: Incomplete Spinal Cord Injury
Spinal Cord Injury, Muscle Spasticity
Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
Normally, nerve fibers carry electrical impulses through the spinal cord, providing communication between the brain and the arms and legs.
- Trial name
- NCT00041717
- Testing
- Fampridine-SR
- Where
- 45 sites in United States, Canada
- Volunteers
- 213 people
- Sponsor
- Acorda Therapeutics
Acute Traumatic Spinal Cord Injury
NEUROwave - Extracorporeal Shock Wave Therapy (ESWT) in Acute Traumatic Complete (AIS A) and Incomplete (AIS B-D) Cross-sectional Lesions on Motor and Sensory Function Within Six Months After Injury
It has been hypothesized that there are two mechanisms of acute traumatic spinal cord injury (SCI): the primary mechanical damage and the secondary injury due to additional pathological processes initiated by the primary injury.
- Trial name
- NCT04474106
- Testing
- Shock waves, dummy head
- Where
- 15 sites in Austria
- Volunteers
- 246 people
- Sponsor
- AUVA
Incomplete Spinal Cord Injury, Muscular Dystrophy
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Background: Cerebral palsy (CP) is the most common motor disorder in children. CP often causes crouch gait, an abnormal way of walking. Knee crouch has many causes, so no single device or approach works best for everybody.
- Conditions
- Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
- Trial name
- NCT01961557
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Spinal Cord Injuries, Complete Spinal Cord Injury
The Efficacy and Safety of a New Power Exoskeleton Robot for Improving Walking Ability in Spinal Cord Injury Patients
In Taiwan, there are more than 23,000 individuals with spinal cord injuries (SCI, mean age: 27 years), with an increment of new 1,200 SCI individuals each year.
- Conditions
- Spinal Cord Injuries, Complete Spinal Cord Injury, Incomplete Spinal Cord Injury
- Trial name
- NCT03548649
- Testing
- exoskeleton robot training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Spinal Cord Injuries (SCI)
Patient and Clinician Perceptions of Safe Ambulation in Incomplete Spinal Cord Injury
This observational cross-sectional study aims to investigate the relationship between patient and therapist perceptions of safe ambulation and objective clinical outcomes in individuals with incomplete spinal cord injury (iSCI).
- Trial name
- NCT07139652
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injury
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
Background: Body weight supported (BWS) locomotor training improves overground walking ability in individuals with motor-incomplete spinal cord injury (SCI).
- Trial name
- NCT01095380
- Testing
- Locomotor training
- Volunteers
- 74 people
- Sponsor
- University of Miami
Spinal Cord Injuries (Complete and Incomplete)
Pilot Testing of Vagus Nerve Stimulation for Early Spinal Cord Injury Recovery
This study looks at a treatment called transcutaneous auricular vagus nerve stimulation, or taVNS. taVNS uses a small device worn on the ear to gently stimulate a nerve.
- Trial name
- PIVOTS-Rehab (NCT07562113)
- Testing
- Transauricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injury Cervical
Blood Flow-restricted Resistance Exercise to Promote Muscle Strength and Use in Adults With Incomplete Spinal Cord Injury
Recovery of arm and hand motor control is critical for independence and quality of life following incomplete spinal cord injury (iSCI).
- Trial name
- NCT06907381
- Testing
- Blood flow-restricted resistance exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Quality Living, Inc.
Neurogenic Bladder, Incomplete Spinal Cord Injury
Effects Of App-Supported Transitional Care On Neurogenic Bladder In Spinal Cord Injury Patients
This is a single-blind randomized controlled trial for patients with neurogenic bladder after incomplete spinal cord injury. Participants are randomly divided into two groups.
- Trial name
- NCT07641101
- Testing
- Mobile Application Based Transitional Care, routine standardized inpatient bladder nursing
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xiamen University
Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injuries (SCI)
Feasibility of Transcutaneous Spinal Stimulation in Rehabilitation
Transcutaneous spinal stimulation (TSS) is a non-invasive neuromodulation approach that delivers electrical stimulation to spinal nerve roots through electrodes placed over the spinal cord.
- Conditions
- Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injuries (SCI), Spinal Cord Injuries and Disorders (SCI/D)
- Trial name
- NCT07898150
- Testing
- Transcutaneous Spinal Stimulation, Inpatient SCI Physiotherapy, Inpatient SCI Occupational Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Janelle Unger
Spinal Cord Injuries
Assessment of the Efficacy and Safety of EESS in Patients With Incomplete Spinal Cord Injuries
Neurological disability caused by traumatic lesions of the spinal cord is a significant challenge for medicine and society. These lesions, leading to sublesional central nervous system dysfunction, include sensorimotor…
- Trial name
- Parastim (NCT04496609)
- Testing
- Stimulation and automated rehabilitation / automated rehabilitation, Automated rehabilitation / Stimulation and automated rehabilitation
- Where
- 2 sites in France
- Volunteers
- 14 people
- Sponsor
- Hopital Foch
Incomplete Spinal Cord Injury, Spastic Tetraplegia
Correlation Between Clinical Assessment and Neurophysiological Assessment in Spinal Cord Injury
This study is a cross-sectional study that aims to explore the correlation between clinical assessment and neurophysiological assessment in SCI.
- Conditions
- Incomplete Spinal Cord Injury, Spastic Tetraplegia, Spastic Paraplegia, Spinal Cord Injury
- Trial name
- NCT06680063
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Stroke, Gait Disorders, Neurologic
ZEPU AI9 Exoskeleton Rehabilitation Robot
The goal of this clinical trial is to learn whether the ZEPU AI9 lower limb exoskeleton robot is feasible, safe, and effective for people with walking difficulty caused by stroke, incomplete spinal cord injury, or orthopedic…
- Conditions
- Stroke, Gait Disorders, Neurologic, Spinal Cord Injuries, Incomplete, Postoperative Complication
- Trial name
- NCT07750808
- Testing
- ZEPU-AI9 Lower Limb Exoskeleton Gait Training, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Spinal Cord Injuries
Transcutaneous Spinal Cord Stimulation in Children With Incomplete Spinal Cord Injury
Aim 1: Determine the safety and feasibility of administration of TSCS to children in a clinical setting. Participants will be randomly assigned to experimental (TSCS) or control (sham stimulation) groups.
- Trial name
- NCT06242873
- Testing
- Gait training with/without TSCS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Neuromodulation With Spinal Stimulation Methods
This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled.
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Paraplegia, Spinal, Paraplegia, Incomplete
- Trial name
- NCT06272279
- Testing
- spinal stimulation-DCS, spinal stimulation-EPS
- Where
- 2 sites in Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Stroke, Incomplete Spinal Cord Injury
ZEPU-AI5 Strength Training Study (ZEPUAI5RCT)
The goal of this clinical trial is to learn if robot-assisted lower-limb strength and gait training can improve safety, feasibility, and functional recovery in adults aged 18-60 years with lower-limb motor dysfunction due to…
- Conditions
- Stroke, Incomplete Spinal Cord Injury, Gait Impairment Following Orthopedic Surgery
- Trial name
- NCT07735702
- Testing
- Robotic lower-limb gait training (ZEPU-AI5), Standard-of-care rehabilitation (conventional physiotherapy)
- Where
- Bangladesh
- Volunteers
- 51 people
- Sponsor
- Bangladesh Medical University
Incomplete Spinal Cord Injury
Neurofeedback to Improve Spasticity After Incomplete Spinal Cord Injury
After incomplete spinal cord injury (iSCI), many people still have control over their upper and/or lower limbs, but secondary conditions such as spasticity impair the function they have left.
- Trial name
- NCT04849676
- Testing
- visual neurofeedback
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Spinal Cord Injuries, Non Invasive Spinal Stimulation
Development of a Novel Strategy to Analyze the Effect on Gait Using Transcutaneous Spinal Current Stimulation in Incomplete Spinal Cord Injured Patients
To determine whether the combination of non-invasive spinal cord stimulation together with gait rehabilitation reduces spasticity and facilitates recovery of lower limb motor strength and gait function in patients with incomplete…
- Conditions
- Spinal Cord Injuries, Non Invasive Spinal Stimulation, Gait Disorders, Neurologic, Motor Function; Retardation
- Trial name
- NCT07289191
- Testing
- transcutaneous spinal cord stimulation
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut Guttmann
Spinal Cord Injuries (SCI)
RTsMS and Body Weight-support Treadmill Training After Incomplete Spinal Cord Injury
The aim of this study is to assess the feasibility of combining rTsMS with BWSTT for gait and sensorimotor recovery in individuals with incomplete spinal cord injury.
- Trial name
- NCT06886308
- Testing
- Repetitive trans-spinal magnetic stimulation
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- Universidade Federal de Pernambuco
Incomplete Spinal Cord Injury
Myosuit in Incomplete Spinal Cord Injury
The Myosuit is a light-weighted lower extremity soft exosuit which provide assistance during walking. In this study the Myosuit will be tested in the home and community setting in patients with incomplete spinal cord injury.
- Trial name
- NCT05605912
- Testing
- Control, Myosuit
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Sint Maartenskliniek