Clinical trials: Incontinence
Urinary Bladder, Neurogenic, Blood Pressure
Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
This study will incorporate critical cross viscero-visceral intersystem interactions to investigate in a controlled laboratory setting the extent, severity, and frequency of occurrence of autonomic dysreflexia with respect to…
- Conditions
- Urinary Bladder, Neurogenic, Blood Pressure, Autonomic Dysreflexia, Bowel Incontinence
- Trial name
- NCT04193709
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Louisville
Normal Subjects, Fecal Incontinence
Trial to Evaluate Fecobionics in Fecal Incontinence (FI) (NORMAL and ABNORMAL-FI)
The objective is to determine the length-tension properties of the anal sphincters using Fecobionics in normal subjects and FI patients during anal distension and during simulated evacuation.
- Trial name
- NCT05412069
- Testing
- Fecobionics
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- The California Medical Innovations Institute, Inc.
Urinary Urge Incontinence, Stress Urinary Incontinence
Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer
Background: Men who are treated for prostate cancer often develop urinary leakage (incontinence). An experimental device that uses electrical impulses to stimulate pelvic floor muscles and surrounding tissues may help.
- Conditions
- Urinary Urge Incontinence, Stress Urinary Incontinence, Prostatic Hyperplasia
- Trial name
- NCT06161506
- Testing
- Elidah Device
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- National Cancer Institute (NCI)
Urinary Tract Infections, Stress Urinary Incontinence
Prophylactic Antibiotics for Outpatient Urethral Bulking
The purpose of this study is to evaluate whether taking prophylactic (preventative) antibiotics at the time of standard of care clinic-based urethral bulking reduces the risk of post-procedural urinary tract infection (UTI).
- Conditions
- Urinary Tract Infections, Stress Urinary Incontinence, Urinary Incontinence
- Trial name
- NCT07501065
- Testing
- Bactrim (800/160 mg), Keflex (500 mg), Cipro (250 mg), or Macrobid (100mg)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Stress Urinary Incontinence
Feasibility of Resisted Expiratory Muscle Training for Females Assigned at Birth With Stress Urinary Incontinence: A Pilot Study
The goal of this randomized pilot study is to determine whether adding expiratory muscle strength training (EMST) to standard pelvic floor muscle training (PFMT) is feasible and may help improve stress urinary incontinence (SUI)…
- Trial name
- NCT07905586
- Testing
- Pelvic floor muscle training, Expiratory muscle strength training
- Volunteers
- 24 people
- Sponsor
- Thomas Jefferson University
Bulkamid® for Urinary Incontinence, Urinary Incontinence
Quantity of Bulkamid® After Injection for Urinary Incontinence
Bulkamid filler is a gel that we use very regularly to treat female urinary leakage during exercise. It is a minimally invasive technique which is increasingly used around the world because it has almost no adverse effects…
- Conditions
- Bulkamid® for Urinary Incontinence, Urinary Incontinence, Ultrasound
- Trial name
- BULKA3D (NCT07900880)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Bulkamid® for Urinary Incontinence, Urinary Incontinence
Perineal Ultrasound After Bulkamid® Injection for Urinary Incontinence
There are currently different treatment options in the management of stress urinary incontinence (SUI). Given a risk of complications inherent to prosthetic reinforcement and numerous current controversies over the use of a…
- Conditions
- Bulkamid® for Urinary Incontinence, Urinary Incontinence, Ultrasound
- Trial name
- BULKPOS (NCT07900906)
- Testing
- Improvement in patients' symptoms
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Fecal Incontinence
The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence
This multicenter clinical trial evaluates ramosetron and psyllium for adults with fecal incontinence, which is the accidental loss of stool.
- Trial name
- SERAFI (NCT06166615)
- Testing
- Ramosetron, Psyllium
- Where
- 3 sites in South Korea
- Volunteers
- 147 people
- Sponsor
- Seoul National University Hospital
Urinary Incontinence
Augmenting Urinary Reflex Activity: Study 3
AURA-3 study (Augmenting Urinary Reflex Activity Study 3) is a single arm, short-duration (8 month) cohort follow up study of preceding interventional medical device study, AURA-2.
- Trial name
- AURA-3 (NCT06597994)
- Testing
- Amber UI system
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Amber Therapeutics Ltd
Overactive Bladder (OAB), Urinary Urgency
APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women
The APPROVE trial is a multi-centered, randomized controlled trial designed to assess differences in symptom improvement, quality of life, bladder symptoms, satisfaction with treatment and continued treatment efficacy in women…
- Conditions
- Overactive Bladder (OAB), Urinary Urgency, Urinary Urge Incontinence (UUI), Nocturia
- Trial name
- APPROVE (NCT06797245)
- Testing
- RiSolve App, AUGS Patient Handouts
- Where
- 10 sites in United States
- Volunteers
- 596 people
- Sponsor
- Medstar Health Research Institute
Urology, Urinary Bladder, Overactive
Ambulatory Long Length URodynamics Evaluation
A prospective, open-label, single arm interventional trial evaluating the safety and performance of the in-clinic and extended monitoring of the lower urinary tract using the Glean Urodynamics System.
- Conditions
- Urology, Urinary Bladder, Overactive, Benign Prostatic Hyperplasia, Urodynamics
- Trial name
- ALLURE (NCT07425015)
- Testing
- Glean Urodynamics System
- Where
- 9 sites in United States
- Volunteers
- 101 people
- Sponsor
- Bright Uro
MRI in Evaluation of Fecal Incontinence
Fecal Incontinence (FI) is a Debilitating Physical and Psychological Disorder Characterizedbytheinvoluntary Loss of Flatus or Liquid/Solid Stool.
Fecal incontinence (FI) is a debilitating physical and psychological disorder characterizedbytheinvoluntary loss of flatus or liquid/solid stool.
- Trial name
- NCT07898748
- Testing
- 3DendoanalultrasoundversusexternalphasedarrayMRI inevaluationoffecal Incontinence
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assiut University
Incontinence-associated Dermatitis, Decubitus Ulcer
Safety and Efficacy of RashEndZ Wound Aeration Technology
The aim of this study is to determine the safety and efficacy of RashEndZ therapeutic liner technology and Dynamic Oxygen Skin Therapy in improving symptoms and expediting healing of IAD and DU in adult patients.
- Trial name
- NCT07899060
- Testing
- Dynamic Oxygen Skin Therapy (DOST), Standard Wound Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- RashEndZ Inc.
Stress Urinary Incontinence (SUI)
Comparison of Two Autologous Sling Procedures for Stress Urinary Incontinence in Women
This study compares two operations for stress urinary incontinence in adult women. Stress urinary incontinence means leaking urine during activities such as coughing, sneezing, laughing, or exercising.
- Trial name
- NCT07899450
- Testing
- Transobturator Autologous Vaginal Wall Sling, Autologous Rectus Sheath Pubovaginal Slinge
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mohamed Ehab Saad Fadl
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate
Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence (SUI), Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-BIPO (NCT07893548)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Benha University
Stress Urinary Incontinence (SUI)
A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)
Prospective, multicenter, single-arm study
- Trial name
- SOPHIA2 (NCT06968741)
- Testing
- Artificial Urinary Sphincter (AUS)
- Where
- 21 sites in United States, France
- Volunteers
- 140 people
- Sponsor
- UroMems SAS
Urinary Incontinence, Medical Device Discomfort
Tolerance, Use and Performance of the PEASY Urine Collection Device in Hospitalized Patients
At present, 3 types of urine collection device can be distinguished: absorbent devices (diaper-type), penile clamps and penile collection sheaths.
- Trial name
- TUPELO (NCT07028996)
- Testing
- Daily use of the PEASY urine collection device for 5 days, Daily collection of patient feedback using a visual analog scale (0-100)
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Urinary Incontinence (UI), Prostatectomy
Transcutaneous Tibial Nerve Stimulation for Urinary Incontinence After Radical Prostatectomy
Urinary incontinence (UI) after radical prostatectomy (RP) is a common postoperative complication that significantly affects quality of life.
- Trial name
- NCT07742176
- Testing
- Active Transcutaneous Tibial Nerve Stimulation (TTNS), Pelvic Floor Muscle Training (PFMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Pamukkale University
Urinary Incontinence, Mixed Urinary Incontinence
Comparing the Effect of Two Types of Pelvic Floor Muscle Stimulation Devices to Improve Symptoms of Urinary Incontinence in Women.
This randomized, parallel-group, non-inferiority clinical trial will compare electromagnetic chair therapy with standard electrostimulation combined with biofeedback in 58 adult women with mixed urinary incontinence.
- Conditions
- Urinary Incontinence, Mixed Urinary Incontinence, Urinary Incontinence (UI), Stress Urinary Incontinence (SUI)
- Trial name
- ESEMS (NCT07792031)
- Testing
- Electromagnetic chair therapy, Electrical stimulation therapy
- Where
- 2 sites in Argentina
- Volunteers
- 58 people
- Sponsor
- Espacio Gaspar Clinic