Clinical trials: Incontinence, open to volunteers
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Encopresis With Constipation and Overflow Incontinence
Senna vs. Polyethylene Glycol 3350 for the Treatment of Retentive Encopresis in Children
The goal of this clinical trial is to learn which treatment is more effective for children with functional constipation (FC) and fecal incontinence (FI), also called retentive encopresis.
- Trial name
- NCT07604025
- Testing
- PEG 3350, Senna
- Where
- 2 sites in Israel
- Volunteers
- 80 people
- Sponsor
- Shaare Zedek Medical Center
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Patch Electrode
UCon is a medical device for treating the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behavior of the bladder/bowel musculature e.g.…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Nocturia, Urinary Frequency More Than Once at Night
- Trial name
- NCT06754189
- Testing
- Time Limited stimulation
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- InnoCon Medical
Low Anterior Resection Syndrome (LARS)
Evaluating the Optimal Timing of Trans-Anal Irrigation for Low Anterior Resection Syndrome Post-rectal Cancer Surgery
This study aims to evaluate the optimal timing of trans-anal irrigation (TAI) for participants with low anterior resection syndrome (LARS) who have undergone surgery for rectal cancer.
- Trial name
- EARLY-TAI (NCT07696689)
- Testing
- Water-based transanal irrigation system
- Volunteers
- 250 people
- Sponsor
- Simona Ascanelli
Primary Nocturnal Enuresis, Nocturnal Enuresis in Children
Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis
The aim of this randomized controlled trial is to evaluate the effects of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) in children with Primary Monosymptomatic Nocturnal Enuresis (PMNE) who are undergoing desmopressin…
- Trial name
- NCT06883851
- Testing
- Structured pelvic floor rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bahçeşehir University
Urinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS)
Reducing Disparities in Urinary Control Symptoms for Minority Women
The study is designed to address the disparity in available conservative/behavioral treatments for UI/LUTS. The program was developed by experts from urogynecology, psychology, and physical therapy then modified based on focus…
- Conditions
- Urinary Incontinence (UI), Lower Urinary Tract Symptoms (LUTS), Pelvic Floor Disorder
- Trial name
- SUPPORT (NCT06798311)
- Testing
- SUPPORT workbook
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Perianal Abscess, Anal Fistulas
Multicenter Study for Diagnosis and Treatment of Perianal Abscesses
Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife.
- Conditions
- Perianal Abscess, Anal Fistulas, Incontinence
- Trial name
- NCT02306382
- Testing
- Perianal abscess drainage, 3D ultrasonography
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Umeå
Incontinence, Prolapse
A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas
There are 3 aims of this study. In Aim 1 community patient partners will be enrolled to help guide the research being performed in all of the aims.
- Trial name
- TIPPS-Urogyn (NCT06679621)
- Testing
- Telehealth intervention
- Where
- United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Overactive Bladder (OAB), Urge Incontinence
Assessing the Genitourinary Microbiome of Women With Overactive Bladder Undergoing Onabotulinum Toxin Type A Intradetrusor Injections
Single-site prospective observational pilot feasibility study of women with overactive bladder/urge urinary incontinence undergoing onabotulinum toxin type A intradetrusor injections in order to achieve the following objectives…
- Trial name
- MICROAB_Pilot (NCT07025044)
- Testing
- onabotulinum toxin type a
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alexis Dieter
Stress Urinary Incontinence (SUI), Sexual Dysfunction
Effect of Knack Pelvic Floor Contraction on Sexual Dysfunction
This study aims to investigate the effect of knack pelvic floor contraction on sexual dysfunction in females with stress urinary incontinence.
- Trial name
- NCT07145216
- Testing
- Interfrential stimulation, Knack pelvic floor training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pelvic Floor Dysfunction, Urinary Incontinence
Impact of Equestrian Sports, CrossFit, and Gym Training on Pelvic Floor Health (PELFISPORT )
This observational cross-sectional study investigates the impact of equestrian sports, CrossFit, and gym training on pelvic floor health in both athletes and non-athletes.
- Conditions
- Pelvic Floor Dysfunction, Urinary Incontinence, Pelvic Organ Prolapse (POP), Chronic Pelvic Pain
- Trial name
- PELFISPORT (NCT06848634)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Stress Urinary Incontinence
Post Market Clinical Follow-up Study on TVT ABBREVO® Continence System
The objective of this single arm, post market, clinical study is to evaluate the performance of Gynecare TVT ABBREVO® Continence System in women undergoing Mid-urethral sling surgery for Stress Urinary Incontinence (SUI).
- Trial name
- NCT04829357
- Testing
- Intervention
- Where
- 4 sites in United States, Italy and 1 more
- Volunteers
- 195 people
- Sponsor
- Ethicon, Inc.
Stress Urinary Incontinence (SUI)
The Effect of Different Delivery Positions on Pelvic Floor Function.
This study is a prospective, multicenter, randomized controlled trial. Baseline data will be collected from eligible subjects recruited during the third trimester of pregnancy.
- Trial name
- NCT07081321
- Testing
- Lithotomy position, Lateral Position, Upright Position
- Where
- China
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
Aquarius Pilot Study to Evaluate the New Axonics Trial System
Evaluation of the new Axonics External Trial System (ETS-02) in patients with overactive bladder (OAB) and/or fecal incontinence (FI).
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI), Overactive Bladder (OAB)
- Trial name
- NCT07335484
- Testing
- Axonics External Trial System (ETS)
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people
- Sponsor
- Axonics, Inc.
Stress Urinary Incontinence
Impact of Virtual Reality Pelvic Floor Training on Postpartum Stress Urinary Incontinence
This study will be conducted to determine the effect of virtual reality (VR) on pelvic floor training on postpartum stress urinary incontinence (SUI) .
- Trial name
- NCT07455838
- Testing
- Pelvic floor muscle rehabilitation supported by an immersive VR, Medical treatment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dysfunctional Voiding, Stress Incontinence, Urinary
Case Control Study to Investigate the Use of Urethral Pressure Profile Measurement in Children
The bladder has a muscle that acts like a tap called the sphincter. Just like a tap, when pee is stored the sphincter muscle is closed and during peeing the sphincter opens.
- Trial name
- NCT04147793
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College London
Stress Urinary Incontinence (SUI), Postmenopausal Women
The Effectiveness of Combined Pelvic Floor Muscle Training and Vaginal Oestrogen Therapy in Postmenopausal Women With Stress Urinary Incontinence
The objective of this clinical trial is to investigate whether the combination of pelvic floor muscle training (PFMT) and topical estrogen is more effective in treating stress urinary incontinence (SUI) in postmenopausal women…
- Trial name
- NCT07186985
- Testing
- Combined Pelvic Floor Muscle Training and Vaginal Oestrogen Therapy, Vaginal estrogen
- Volunteers
- 115 people
- Sponsor
- Hanoi Medical University
Stress Urinary Incontinence (SUI)
Differences in Pelvic Floor Motion Level Among Chinese Women and Construction of an Assessment System
The purpose of this study is to integrate millimeter-wave radar technology to investigate the dynamic movement characteristics of the pelvic floor muscles in patients with different Body Mass Index (BMI) and stress urinary…
- Trial name
- NCT07608146
- Where
- 20 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Stress Urinary Incontinence (SUI)
The Effects of Expiratory Muscle Strength Training in Women With Stress Urinary Incontinence
The aim of this study is to investigate the effects of expiratory muscle strength training in addition to pelvic floor muscle training in women with stress urinary incontinence.
- Trial name
- NCT07693920
- Testing
- Pelvic Floor Muscle Training, Expiratory muscle strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mustafa Kemal University
Male Erectile Disorder, Prostate Cancer
Focal Therapy for Prostate Cancer Using HIFU
RATIONALE: Prospective trials using hemi-ablation with high intensity focused ultrasound (HIFU) (Sonablate 500) have demonstrated feasibility, safety, and encouraging functional outcomes and early cancer control with 90% of men…
- Conditions
- Male Erectile Disorder, Prostate Cancer, Therapy-related Toxicity, Urinary Incontinence
- Trial name
- INDEX (NCT01194648)
- Testing
- questionnaire administration, assessment of therapy complications, high-intensity focused ultrasound ablation
- Where
- United Kingdom
- Volunteers
- 354 people
- Sponsor
- University College, London