Clinical trials: Incontinence
Stress Incontinence
Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence
This project will determine whether post-operative prophylaxis with macrobid will decrease the incidence of postoperative urinary tract infection in women receiving sub-urethral slings for the treatment of urinary incontinence.
- Trial name
- NCT00734968
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Urinary Incontinence, Retention, Urinary
Performance of a Single-use Intermittent Micro-hole Zone Catheter
The goal of this randomized, controlled crossover study was to assess the performance of a new micro-hole zone catheter compared to a conventional 2-eyelet catheter in 42 male intermittent catheter users.
- Trial name
- NCT05485922
- Testing
- Investigational device - intermittent catheter with a micro-hole zone, Comparator device -VaPro intermittent catheter
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Coloplast A/S
Stress Urinary Incontinence
Exploratory Trial of TAS-303 in Female Patients With Stress Urinary Incontinence
The purpose of this study is to evaluate the efficacy and safety of TAS-303 in female patients with stress urinary incontinence.
- Trial name
- NCT02906683
- Testing
- TAS-303
- Where
- Japan
- Volunteers
- 337 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Urinary Urge Incontinence
InterStim® Amplitude Study
This feasibility study will explore the effects of three different InterStim amplitude settings on overactive bladder symptoms (OAB).
- Trial name
- NCT03335761
- Testing
- InterStim Therapy
- Where
- 18 sites in United States, Belgium and 5 more
- Volunteers
- 97 people
- Sponsor
- MedtronicNeuro
Fecal Incontinence
Fecal Microbial Transplantation for the Treatment of Fecal Incontinence in Women
Open label pilot study assessing FMT to treat fecal incontinence in women 50 years of age and older.
- Trial name
- FMT for FI (NCT04201821)
- Testing
- fecal microbial transplantation (FMT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Fecal Incontinence
A Feasibility Study of a Fecal Incontinence Management System for Medical Use
The purpose of this feasibility study is to evaluate the performance and skin-friendliness of the barrier of the Fecal Incontinence Management System.
- Trial name
- NCT00556972
- Testing
- Fecal Incontinence Management System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Coloplast A/S
Urinary Incontinence
TOMUS-Trial Of Mid-Urethral Slings
The primary aim of this clinical trial is to compare treatment success for two minimally invasive surgical procedures to treat stress urinary incontinence in women. These procedures are called mid-urethral slings.
- Trial name
- TOMUS (NCT00325039)
- Testing
- retropubic mid-urethral sling (TVT), transobturator mid-urethral sling (TVT-O and the Monarc)
- Where
- 11 sites in United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Stress Urinary Incontinence
GTx-024 as a Treatment for Stress Urinary Incontinence in Women
The purpose of this study is to determine whether GTx-024 is safe and effective in the treatment of stress urinary incontinence in postmenopausal women.
- Trial name
- NCT02658448
- Testing
- GTx-024
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- GTx
Urinary Incontinence
A Study to Assess Efficacy and Safety With Solifenacin Succinate to Improve Urinary Continence After Robotic Assisted Radical Prostatectomy
The purpose of this study is to assess the efficacy and safety of 12 weeks of treatment of solifenacin succinate versus placebo in participants who are incontinent after Robotic Assisted Radical Prostatectomy.
- Trial name
- NCT01371994
- Testing
- solifenacin succinate
- Where
- 60 sites in United States, Canada
- Volunteers
- 640 people
- Sponsor
- Astellas Pharma Inc
Fecal Incontinence
Educational-Medical-Behavioral Treatment of Fecal Incontinence
In previous studies at a university referral center the investigators demonstrated that a multicomponent conservative treatment for fecal incontinence was effective.
- Trial name
- FIX (NCT01717456)
- Testing
- Education, Fiber supplements, Laxatives or anti-diarrheals
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of North Carolina, Chapel Hill
Urinary Incontinence
Acupuncture for Urinary Incontinence
This research study will evaluate the effectiveness of acupuncture in decreasing urinary incontinence (involuntary urine loss) in women. The study will involve 12 acupuncture sessions over 6 weeks.
- Trial name
- NCT00297427
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- University of Pittsburgh
Stress Urinary Incontinence
Comparison of the Viveve Treatment and Cryogen-Only Treatment Versus Sham Treatment for Stress Urinary Incontinence
This is a prospective, randomized, single-blind, study comparing both the Viveve Treatment (RF plus cryogen) and cryogen alone treatment versus sham treatment in patients with mild to moderate stress urinary incontinence.
- Trial name
- NCT04206085
- Testing
- Viveve - Active, Viveve - Cryogen-Alone
- Where
- 3 sites in Canada
- Volunteers
- 38 people
- Sponsor
- Viveve Inc.
Overactive Bladder
Study of Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence
The purpose of this study is to assess the safety and effectiveness of botulinum toxin type A (onabotulinumtoxinA) in treating patients with idiopathic overactive bladder with urinary incontinence.
- Trial name
- NCT00910845
- Testing
- onabotulinumtoxinA, normal saline
- Where
- 2 sites in United States, Canada
- Volunteers
- 557 people
- Sponsor
- Allergan
Neurogenic Overactive Bladder, Urinary Incontinence
Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
The study is designed to demonstrate that treatment with low level stimulation of the bladder muscles reduces symptoms of urinary incontinence in comparison with no stimulation.
- Conditions
- Neurogenic Overactive Bladder, Urinary Incontinence, Detrusor Overactivity
- Trial name
- ACCEPTANCE (NCT01023269)
- Testing
- InterStim Therapy
- Where
- 8 sites in Belgium, France and 4 more
- Volunteers
- 17 people
- Sponsor
- MedtronicNeuro
Stress Urinary Incontinence
The Prefyx PPS™ System eRegistry
Registry to gather information about the long term use of the Prefyx PPS System for the treatment of Stress Urinary Incontinence (SUI).
- Trial name
- NCT00688181
- Testing
- The Prefyx PPS™ Pre-pubic Sling System
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Boston Scientific Corporation
Overactive Bladder, Urinary Urge Incontinence
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
The purpose of this study is to test whether using belladonna \& opiate suppositories (B\&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder…
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Bladder, Neurogenic, Painful Bladder Syndrome
- Trial name
- ROBIN (NCT02600715)
- Testing
- Onabotulinumtoxin A (BoNT), belladonna, Morphine
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Edgar LeClaire, MD
Overactive Bladder
Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation
The aim of this study is to determine the efficacy of an accelerated course for percutaneous tibial nerve stimulation (PTNS) induction to treat overactive bladder symptoms.
- Trial name
- NCT03547518
- Testing
- PTNS treatment
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Corewell Health East
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Constipation, Fecal Incontinence
A Colonic Tube to Improve Bowel Function in Spinal Cord Injury
The investigators want to know if placing a tube through the skin and into the colon to flush out the colon is safe and effective in helping spinal cord Veterans with bowel management.
- Conditions
- Constipation, Fecal Incontinence, Spinal Cord Injury
- Trial name
- NCT00345397
- Testing
- Percutaneous endoscopic colostomy (PEC) tube
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Catheter-Associated Urinary Tract Infection
Prevention of Catheter-Associated Urinary Tract Infection in Incontinence and Reconstructive Pelvic Surgery Patients
The study will assess the risk of catheter associated urinary tract infection in women undergoing incontinence or reconstructive pelvic surgery. Women will be given an antibiotic or placebo at the time of catheter removal.
- Trial name
- PRECAUTION (NCT01108757)
- Testing
- Bactrim
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic