Clinical trials: Incontinence Bowel
Rectal Cancer
The Longitudinal Study of Low Anterior Resection Syndrome in Patients with Newly Diagnosed Rectal Cancer.
The aims are to identify the trajectory of LAR Syndrome and explore the adaptation process and coping strategies of LAR Syndrome in patients newly diagnosed with rectal cancer.
- Trial name
- NCT05445245
- Where
- Taiwan
- Volunteers
- 125 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Anal Fissure
Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure
This study is aimed at studying the effectiveness and safety of surgical treatment of chronic anal fissure.
- Trial name
- BTATCAF (NCT05598164)
- Testing
- Botulinum toxin type A
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Sacral Neuromodulation
Preliminary Outcomes of Sacral Neuromodulation Applications; Tertiary-Center Experience in Turkey
to report our patients' outcomes of SNM in tertiary health centres in Turkey
- Trial name
- NCT06098963
- Testing
- sacral neuromodulation
- Volunteers
- 16 people
- Sponsor
- Cigli Regional Training Hospital
Fecal Incontinence
The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal Incontinence
This multicenter clinical trial evaluates ramosetron and psyllium for adults with fecal incontinence, which is the accidental loss of stool.
- Trial name
- SERAFI (NCT06166615)
- Testing
- Ramosetron, Psyllium
- Where
- 3 sites in South Korea
- Volunteers
- 147 people
- Sponsor
- Seoul National University Hospital
Anorectal Malformation
National Study on the Quality of Life of Patients With Anorectal Malformation
Anorectal malformations, occurring approximately 1 in 5000 live births, mainly involve the distal anus and rectum, but also sometimes the urinary and genital tracts.
- Trial name
- MARQOL (NCT02029248)
- Testing
- Quality of life questionnaire
- Where
- 37 sites in France
- Volunteers
- 762 people
- Sponsor
- Nantes University Hospital
Fecal Incontinence in Old Age, Urinary Incontinence in Old Age
Community-Based Continence Promotion: Sustaining Healthy Aging in Place (SHAIP) Through Mind Over Matter (MOM)
The goal of this study is to obtain data about the effectiveness, reach, adoption, and implementation potential of an innovative, combined urinary/bowel continence workshop through a randomized controlled trial in six Wisconsin…
- Trial name
- SHAIP (NCT03140852)
- Testing
- Mind Over Matter; Healthy Bowels, Healthy Bladder
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Faecal Incontinence, Chronic Constipation
Outcome Research in Bowel Irrigation Techniques for the Treatment of Chronic Constipation and/or Faecal Incontinence
This clinical investigation is a post-market, exploratory, randomised, parallel, open-label investigation comparing two UKCA/CE-marked transanal irrigation products for the management of faecal incontinence and/or chronic…
- Trial name
- ORBIT-1 (NCT07473622)
- Testing
- Transanal irrigation
- Volunteers
- 66 people
- Sponsor
- Qufora A/S
Faecal Incontinence
Fecal Incontinence Type Assessment Scale
Urge faecal incontinence (FI) and passive FI are the two subgroups of FI described by the International Continence Society. Urge FI is described as "the inability to defer defecation once the urge is perceived for long enough to…
- Trial name
- NCT04410822
- Testing
- Clinical tests
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Gérard Amarenco
Rectal Cancer
Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)
Primary hypothesis: Side-to-end anastomosis is non-inferior to colon J pouch for reconstruction after low anterior resection for rectal cancer in fecal incontinence (Wexner score).
- Trial name
- SAVE (NCT01006577)
- Testing
- side-to-end anastomosis, colon j pouch
- Where
- Germany
- Volunteers
- 306 people
- Sponsor
- Charite University, Berlin, Germany
Chronic Constipation
Anorectal Manometery in Pediatric Chronic Refractory Constipation
Anorectal manometry and high-resolution anorectal manometry (HRAM) are becoming the investigation of choice for understanding the pathophysiology of chronic constipation with or without fecal incontenance in children in many…
- Trial name
- NCT06543979
- Testing
- lubiprostone , single arm, biofeed back sessions, botox injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Fecal Incontinence
Comparison of Rectal Trumpet and Standard Care
Primary: To determine the effectiveness of the rectal trumpet compared to the standard care in maintaining skin integrity in patients with fecal incontinence.
- Trial name
- NCT00307476
- Testing
- Rusch Nasopharyngeal Airway
- Where
- 2 sites in United States
- Sponsor
- Christiana Care Health Services
Rectum Cancer, Quality of Life
Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Cancer.
Background: Patients treated for rectal cancer are in high risk of developing poor quality of life and faecal incontinence. Faecal incontinence has a negative impact on quality of life.
- Conditions
- Rectum Cancer, Quality of Life, Faecal Incontinence, Low Anterior Resection Syndrome
- Trial name
- EDFI-Cohort (NCT03257332)
- Testing
- Low Anterior Resection for Rectum Cancer
- Where
- 2 sites in Denmark
- Sponsor
- Slagelse Hospital
Fecal Incontinence
BTL Emsella Chair Versus Sham for the Treatment of Fecal Incontinence
The purpose of this clinical trial is to compare the Emsella Chair to sham and to determine whether electromagnetic technology is effective in the treatment of fecal incontinence.
- Trial name
- NCT04138602
- Testing
- BTL Emsella
- Where
- United States
- Sponsor
- Corewell Health East
Fecal Incontinence
Effects of an Anal Insert Device in Fecal Incontinence
The purpose of this research is to test the effects of an inserted anal device on fecal incontinence (accidental bowel leakage) in patients who have persistent symptoms despite other conservative therapy.
- Trial name
- NCT03898778
- Testing
- Minnesota Medical Technologies Anal Insert Device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Minnesota Medical Technologies
Dysphagia, Fecal Incontinence
Evaluation of Potential Vitamin D Effects on Muscle: a Pilot Study
People who do not have adequate amounts of vitamin D develop weakness of leg and arm muscles. This study will determine if vitamin D supplementation benefits muscle functions important for swallowing, bladder and bowel function.
- Conditions
- Dysphagia, Fecal Incontinence, Urinary Incontinence
- Trial name
- NCT00593996
- Testing
- Ergocalciferol (vitamin D2)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Fecal Incontinence
Treatment of Faecal Incontinence With Sacral Nerve Stimulation - Improved Function With Stimulation Bilaterally?
Faecal incontinence is a devastating condition causing psychological stress, affecting daily living and influences quality of life. Faecal incontinence affects 2,2 to 5 % of the adult population.
- Trial name
- SNS (NCT00913601)
- Testing
- Medtronic INTERSIM II - 3058
- Where
- Denmark
- Volunteers
- 29 people
- Sponsor
- University of Aarhus
Massage
Massage With Senna-based Laxatives Versus Senna-based Laxatives in Managing Overflow Retentive Stool Incontinence
This study aimed to evaluate the effect of abdominal massage with senna-based laxative in managing overflow retentive stool incontinence in pediatrics.
- Trial name
- NCT04273295
- Testing
- Abdominal massage
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- South Valley University
Rectal Cancer, Rectal Neoplasms
Transverse Coloplasty vs. Side-to-end Anastomosis Following Low Anterior Resection (LAR): CSAR Trial
CSAR Trial's aim is to determine whether the transverse coloplasty pouch or the side-to-end anastomosis as rectal reservoir reconstruction offers the best functional results.
- Conditions
- Rectal Cancer, Rectal Neoplasms, Rectal Tumors, Fecal Incontinence
- Trial name
- CSAR (NCT03074461)
- Testing
- Side-to-End Anastomosis, Transverse Coloplasty
- Where
- 3 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Fecal Incontinence
Stem Cells Therapy for Fecal Incontinence in Children After Posterior Sagittal Ano-rectoplasty
The problem of the incontinence imposes considerable strain on the child and their parents. These patients suffer from a long-life handicap and they need support and follow-up.
- Trial name
- NCT02161003
- Testing
- Stem Cells Injection Technique, Stem Cell Isolation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Fecal Incontinence, Dyssynergic Defecation
Home Biofeedback Therapy for Dyssynergic Defecation, Fecal Incontinence and Urinary Incontinence
Biofeedback therapy is an effective treatment for the management of patients with dyssynergic defecation and constipation, urinary incontinence (UI), and fecal incontinence (FI).
- Conditions
- Fecal Incontinence, Dyssynergic Defecation, Urinary Incontinence
- Trial name
- Bioanatoner (NCT05771597)
- Testing
- Home Biofeedback therapy, Office biofeedback therapy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Augusta University