Clinical trials: Independence
Lymphedema, Lymphatic Filariasis
A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in India
Current lymphedema management protocols are based on the use of simple measures of hygiene (regular washing with soap and water, skin and nail care), use of topical antibiotics or antifungal agents, exercise and footwear.
- Conditions
- Lymphedema, Lymphatic Filariasis, Filariasis
- Trial name
- LeDoxy-India (NCT02929121)
- Testing
- Doxycycline
- Where
- India
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- The Task Force for Global Health
Elderly People, Living Alone in a Residence With Care Giver
Comparative Study of QuietCare
The objective of the study is to examine the efficacy and safety of QuietCare in a randomized, open study in elderly subjects living in assisted/ independent living facilities for 6 months.
- Trial name
- NCT01839825
- Testing
- QuietCare
- Where
- Japan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- National Center for Geriatrics and Gerontology, Japan
Aging, Physical Activity
Smart Television and Exercise Promotion for Independent Living Facilities
Physical activity (PA) has physical, emotional, and cognitive benefits for seniors (e.g., increased strength and balance, reduced frailty, fewer falls, improved brain function, lower mortality risk), yet many seniors have limited…
- Trial name
- STEP4Life (NCT03001778)
- Testing
- Usability Testing
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Elevated Blood Sugar
Power of Choice on Autonomy, Motivation, Exercise Adherence, and Cardiorespiratory Fitness
People with elevated blood sugar levels are at increased risk of developing chronic medical conditions such as obesity, type 2 diabetes, and cardiovascular disease.
- Trial name
- NCT03576924
- Testing
- MICT, HIIT, CHOICE
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Periapical Periodontitis
Adrenomedullin Upregulation in Apical Periodontitis
The aim of the present study was to investigate the relationship between Apical periodontitis (AP) severity and inflammatory markers (IL-12, TNF-alpha), and Mid-Regional Pro Adrenomedullin (MR-proADM) in patients with AP.
- Trial name
- NCT05297747
- Testing
- Apical periodontitis, Chronic periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Physical Activity, Aging
Promoting Walking in Older Adults Living in Independent Living Communities in Northern Ireland: A Feasibility Study.
The multi-level 12 week peer-led walking intervention incorporates aspects from all three levels of the ecological model (with the aim of producing sustained (>6months) physical activity behaviour change in older adults living in…
- Conditions
- Physical Activity, Aging, Health Behaviour, Social Isolation
- Trial name
- NCT02596672
- Testing
- The friendly walking group
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Hypercholesterolemia, Hyperlipidemias
Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterol
This study will comprise a randomized controlled, counter-balanced, cross-over trial to evaluate the independent effects of a high cholesterol (high egg), low saturated fat diet and a high saturated fat, low cholesterol diet on…
- Conditions
- Hypercholesterolemia, Hyperlipidemias, Physical Inactivity, Diet, Healthy
- Trial name
- NCT05267522
- Testing
- Egg diet, Egg-free Diet, Control Diet
- Where
- Australia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of South Australia
Healthy
Effects of Dual-task Exercises on Gait Parameters and Cognitive Function in Elderly Women: A Randomized Controlled Trial
The training of a secondary task while walking, whether it is reasoning activities, memory or motor tasks, may enhance automation, walking performance, and postural control and, thus, minimize the risk of falls influenced by the…
- Trial name
- NCT02185157
- Testing
- dual -task exercises, Aerobic training
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Healthy
Movement-Sequence Observation in Healthy Adults: Motor and Cognitive Effects on Effector-Independent Performance
Studies examining the effects of action observation (AO) on ipsilateral versus contralateral upper limb (UL) motor performance have reported mixed findings.
- Trial name
- NCT07531212
- Testing
- Action observation (AO), Sequence observation (SO), Nature Observation (NO)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ariel University
Healthy Elderly, Mild Cognitive Impairment (MCI)
Hand Training Device For Cognitive Care
Previous studies indicated that auditory stimulation as an external cue might have positive impacts on sensorimotor synchronization.
- Trial name
- NCT06417034
- Testing
- Game Software
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Genetic Disease, Nonsense Mutation
Phase 1 Study of ELX-02 in Healthy Adult Subjects
Phase 1 Multiple Ascending Dose Study in Normal Healthy Volunteers
- Trial name
- NCT03309605
- Testing
- ELX-02
- Where
- Belgium
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Eloxx Pharmaceuticals, Inc.
Cataract
Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens
This is a study to assess the spectacle independence and quality of vision of patients receiving the AcrySof® Panoptix® Intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04124952
- Testing
- Panoptix
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SightTrust Eye Institute
Developmental Coordination Disorder, Autism Spectrum Disorder
An Explorative RVA of the Motor Development of Children With DCD <2y
This study compares motor development in three groups of infants (controls, DCD, DCD+ASD) before the age of 2 years using retrospective video analysis of infants in home video contexts.
- Trial name
- RVA_DCD (NCT04126395)
- Testing
- Movement Assessment Battery for Children 2(M-ABC-2), Developmental Coordination Disorder - Questionnaire (DCD-Q), Social Responsiveness Scale 2 (SRS-2)
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Ghent
Immunometabolism, Mitochondrial Function, Bioenergetics
Independent and Combined Effects of Short-term Sulforaphane Supplementation and Exercise on Immunometabolism in Healthy Adults
The study consist of 3 interventional periods which will be completed by each consenting participant in a randomized, crossover fashion. The interventional periods will be separated by a minimum 1 week washout period.
- Conditions
- Immunometabolism, Mitochondrial Function, Bioenergetics, Inflammation
- Trial name
- EXSFN (NCT07668596)
- Testing
- Sulforaphane-rich Broccoli Sprout Extract, High Intensity Interval Treadmill Running
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Oral Cancer, Oral Cavity Cancer
WORST PATTERN OF INVASION IN ORAL SQUAMOUS CELL CARCINOMA
Cancer of the oral mucosa, also known as oral squamous cell carcinoma (OSCC), occurs as an ulceroproliferative lesion that can develop at any site in the mouth, from the lips to oropharynx.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Squamous Cell Carcinoma
- Trial name
- NCT05927220
- Testing
- Biopsy Specimens Histopathology
- Where
- Pakistan
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Pathology Rawalpindi
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Dysphagia, Stroke
Development and Validation of an Online Independent Training Program for TOR-BSST© Dysphagia Screeners
Stroke is a leading cause of death and disability globally. Dysphagia, swallowing difficulty, is common following stroke, affecting about 55% of all stroke patients.
- Trial name
- NCT05379699
- Testing
- TOR-BSST© eLearning Training, Standard TOR-BSST© Training
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Breast Cancer
Nutritional Supplements and Hormonal Manipulations for Breast Cancer Prevention
The overall hypothesis is that the combination of a low dose of the antiestrogen Raloxifene with omega-3 fatty acids will exert a synergistic breast cancer chemopreventive effect due to the crosstalk of their downstream cellular…
- Trial name
- NCT00723398
- Testing
- Lovaza 4gm oral, Raloxifene 60 Mg Oral Tablet, Raloxifene 30 Mg Oral Tablet
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Aging
The Evaluation of Efficacy and Safety of Hyaluronic Acid Injection on Skin Moisturization and Elasticity
STYLAGE® HydroMax is a CE-marketed hyaluronic acid gel intended to improve skin moisturization and elasticity through injection into the dermis of the face, neck, neckline area and back of the hand.
- Trial name
- HYDRELA (NCT04088006)
- Testing
- Injection of STYLAGE® HydroMax
- Where
- France
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Physical Activity, Activity Play
Active Play in After School Programs
Background: Physical activity (PA) is a key component in health promotion and prevention of overweight. Interventions delivered in after-school programs (ASP) have the potential to become a means of ensuring PA among young…
- Conditions
- Physical Activity, Activity Play, Motor Activity, Quality of Life
- Trial name
- NCT02954614
- Testing
- Active play in after school programs (ASP)
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University