Clinical trials: Individual Difference
Individuality
Genetic & Environmental Determinants Of Immune Phenotype Variance: Establishing A Path Towards Personalized Medicine
The purpose of this study is to assess the determinants of immunologic variance within the general healthy population.
- Trial name
- LabExMI (NCT01699893)
- Testing
- unique arm
- Where
- France
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Individuality, Healthy Subjects
Milieu Intérieur Collection - Genetic & Environmental Determinants Of Immune Phenotype Variance
The purpose of this study is to assess the determinants of immunologic variance within the general healthy population.
- Trial name
- MI (NCT03905993)
- Volunteers
- 956 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Solid Tumors
A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
This study is open to adults with different types of advanced cancer. People can take part if previous treatment was not successful, or no treatment exists.
- Trial name
- NCT05471856
- Testing
- BI 1703880, Ezabenlimab
- Where
- 21 sites in United States, Japan and 4 more
- Volunteers
- 66 people
- Sponsor
- Boehringer Ingelheim
Overweight, Obesity
A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight
This study is being done to find out how well a medicine called CagriSema helps people with overweight or obesity lose weight. CagriSema is still being tested in studies and is not yet available for doctors to prescribe.
- Trial name
- NCT07357766
- Testing
- Cagrisema
- Where
- 116 sites in United States, Bulgaria and 12 more
- Sponsor
- Novo Nordisk A/S
Self-Management, Behavior
Development and Feasibility of a Nurse-led Person-centered Education Program
Background Psoriasis is a chronic inflammatory skin disease causing reduced quality of life. Psoriasis patients are often insufficiently informed about their disease with its treatment possibilities leading to non-adherence of…
- Conditions
- Self-Management, Behavior, Patient Empowerment
- Trial name
- PsoEd (NCT05715190)
- Testing
- Education
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- School of Health Sciences Geneva
COVID-19 SARS-CoV-2 Infection
A Phase III Clinical Trial to Evaluate the Efficacy and Safety of SCTV01E in Healthy People
The objective of this study is to evaluate the effectiveness of SCTV01E in healthy people
- Trial name
- NCT05683561
- Testing
- CoronaVac, SCTV01E
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Type 2 Diabetes
A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes
The purpose of the study is to find out if the new tablet formulation oral semaglutide D is equally safe and effective as the approved oral semaglutide for treating Japanese people with type 2 diabetes.
- Trial name
- NCT07271251
- Testing
- Oral semaglutide
- Where
- 15 sites in Japan
- Volunteers
- 267 people
- Sponsor
- Novo Nordisk A/S
Depression - Major Depressive Disorder, Anxiety
Comparative Effects of Acceptance and Commitment Therapy, Cognitive Behavioral Therapy, and Treatment-as-Usual on Depression Among People With Marital Crisis
This parallel three-arm, single-blind (assessor-blinded), randomized controlled trial (RCT) aims to compare the effects of ACT, CBT, and treatment-as-usual (TAU) on the severity of depressive symptoms (primary outcome), the…
- Conditions
- Depression - Major Depressive Disorder, Anxiety, Marital Conflict
- Trial name
- NCT07808021
- Testing
- Acceptance and Commitment Therapy, Cognitive Behavioral Therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Universiti Sains Malaysia
Obesity
Health Benefits of Functional Oil (Mega 3 Fatty Acids From Fish Oil) on Obese People
Examine the effects and safety of functional oil (olive oil with omega 3 fatty acids from fish oil) on different inflammatory markers in obese subjects with dietary intervention for weight lost.
- Trial name
- NOBO (NCT01739998)
- Testing
- functional oil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Frail Elderly Syndrome
Resistance Exercise Training at Different Intensities in Healthy and Frail Older People: A Feasibility Study
After the age of 40-45 years muscle mass and function progressively decline, reducing older peoples' abilities to perform tasks of daily living and also increase the risk of falls.
- Trial name
- NCT03627793
- Testing
- resistance training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Healthy
A Study in Healthy People to See How Zongertinib is Taken up Into the Blood When Given as Tablets Made by Two Different Manufacturers
The main objective of this trial is to establish the bioequivalence of zongertinib tablet from manufacturer 1 (Test, T) compared with zongertinib tablet from manufacturer 2 (reference, R) following oral administration.
- Trial name
- NCT06360081
- Testing
- Zongertinib manufacturer 1, Zongertinib manufacturer 2
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Condition: Healthy
Resting-state Connectivity and Individual Differences in Affective Placebo Responsiveness
Expectation effects on affective states are central to mechanisms relevant for mood disorders and their treatment. This study will test whether inter-individual differences in resting-state functional connectivity (rsFC) within…
- Trial name
- NCT07479966
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stefanie Brassen
Knee Osteoarthritis
A Study of the Effectiveness of Different Types of Exercise for People With Knee Osteoarthritis
This pilot study will test the testing and exercise training protocols for a larger study that is in the desing phase and may be modified based on the findings of this study.
- Trial name
- KBA Exercise (NCT00519922)
- Testing
- Kinesthesia, Balance, and Agility (KBA) Exercise, Standard LE Strength Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Arthritis Research Institute of America
Autism Spectrum Disorder (ASD
Effectiveness of DIR/Floortime™ in Children With Autism Spectrum Disorder
This randomized controlled trial evaluates the efficacy of Integrated DIR/Floortime™ in improving functional emotional development and adaptive behavior in children aged 4-12 years with Autism Spectrum Disorder (ASD).
- Trial name
- DIR-ASD (NCT07758465)
- Testing
- DIR/Floortime, Standard therapy
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Fatima Tabassum
Obesity
CD36 and Human Fat Taste Perception
The purpose of this study is to determine the effect of common human variants in in taste related genes, such as CD36 gene, a putative fat taste receptor, affect fat taste perception.
- Trial name
- FATYP (NCT02699567)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Parkinson's Disease
Turning Pattern of Different Body Segments During Turns and Turning Performance
This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited.
- Trial name
- NCT05929781
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Alcohol Use, Unspecified
Risk Factors for Stress-induced Alcohol Misuse: Genetic Predictors and Mediation by Personality Type
To examine whether variation in 'risk-taking' personality and linked genetic variants predicts susceptibility to, and resilience against, stress-induced alcohol misuse.
- Trial name
- RISK (NCT04533802)
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Gender Dysphoria
Evaluation of the Variation in Quality of Life During Medical Transition for Transgender People.
Transgender people can benefit from psychological, psychiatric, endocrinological support, sexual reassignment surgery, sexology support and dermatological care. The value of transitional care courses is scientifically recognized.
- Trial name
- TRANS'ITION (NCT05273112)
- Where
- 13 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Lille
ESBL Producing E.Coli, ESBL Producing K.Pneumoniae
Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals)
This study investigates carriage rate and risk factors for acquiring multiresistant bacteria (ESBL producing E.coli and K.pneumoniae, carbapenem-resistant and multidrug resistant P.aeruginosa, MRSA and VRE) in hospitalised…
- Conditions
- ESBL Producing E.Coli, ESBL Producing K.Pneumoniae, Multidrug Resistant P.Aeruginosa, Carbapenem Resistant P.Aeruginosa
- Trial name
- ABRESIST (NCT03343119)
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Cognitive Dysfunction
Individual Intervention of Cognitive Stimulation
Population aging in Portugal has led to problematic social issues (American Psychiatric Association, 2013; Spector, Woods \& Orrell, 2008; Wimo \& Prince, 2010).
- Trial name
- NCT05966207
- Testing
- Individual Cognitive Stimulation
- Where
- Portugal
- Volunteers
- 53 people
- Sponsor
- Escola Superior de Enfermagem de Coimbra