Clinical trials: Individual Difference
Individuality
Effects of Hydrocortisone on Social Cognition and Memory
The effects of hydrocortisone on cognition will be investigated.
- Trial name
- CORT-COG (NCT02478021)
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Type 2 Diabetes
A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes
The purpose of the study is to find out if the new tablet formulation oral semaglutide D is equally safe and effective as the approved oral semaglutide for treating Japanese people with type 2 diabetes.
- Trial name
- NCT07271251
- Testing
- Oral semaglutide
- Where
- 15 sites in Japan
- Volunteers
- 267 people
- Sponsor
- Novo Nordisk A/S
Solid Tumors, KRAS Mutation
A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation
This study is open to adults with different types of advanced or metastatic cancer (including lung cancer, colorectal cancer, pancreatic cancer, and bile duct cancer).
- Trial name
- NCT04973163
- Testing
- BI 1823911, BI 1701963, Midazolam
- Where
- 9 sites in United States, Belgium and 2 more
- Volunteers
- 30 people
- Sponsor
- Boehringer Ingelheim
Small Cell Lung Carcinoma, Neuroendocrine Neoplasms
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers
This study is open to adults with small cell lung cancer and other neuroendocrine tumours. The study is in people with advanced cancer for whom previous treatment was not successful or no standard treatment exists.
- Conditions
- Small Cell Lung Carcinoma, Neuroendocrine Neoplasms, Extra-pulmonary Neuroendocrine Carcinoma
- Trial name
- NCT05882058
- Testing
- BI 764532, dose 1, BI 764532, dose 2, Ventana DLL3 RxDx assay
- Where
- 59 sites in United States, Belgium and 10 more
- Volunteers
- 204 people
- Sponsor
- Boehringer Ingelheim
Psychotic Disorders, Metabolic Syndrome x
Is Health Coaching Effective for Improving Metabolic Health in People With Psychosis Disorders?
Antipsychotic medications frequently cause metabolic side-effects, such as abdominal obesity, high blood pressure, cholesterol abnormalities, and blood sugar dysregulation, all of which can lead to what is known as the Metabolic…
- Trial name
- NCT01752465
- Testing
- Health Coaching, Standard care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Overweight, Obesity
A Research Study Looking at the Comparability (Bioequivalence) of Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or Obesity
The study will look at how two different forms of semaglutide reach and stay in the blood after injection. None of the two forms of semaglutide have been approved by the authorities to treat obesity, but it has been approved as a…
- Trial name
- NCT04187300
- Testing
- Semaglutide
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Novo Nordisk A/S
Obstructive Sleep Apnea, Cognitive Change
Cognition After OSA Treatment Among Native American People (CATNAP)
This research project will develop and implement a motivational interviewing and electronic messaging intervention to address obstructive sleep apnea (OSA), positive airway pressure (PAP) adherence, and risk of Alzheimer's…
- Trial name
- CATNAP (NCT06227572)
- Testing
- CATNAP MI
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Washington State University
Diabetes Mellitus, Type 2
A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight
This study compares how three doses of semaglutide work in participants with type 2 diabetes (T2D) and overweight who are taking metformin.
- Trial name
- NCT05486065
- Testing
- Semaglutide
- Where
- 130 sites in United States, Greece and 3 more
- Volunteers
- 245 people
- Sponsor
- Novo Nordisk A/S
Depressive Disorder, Major
A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression
This study is open to adults with depression (major depressive disorder) for whom standard treatment with antidepressants alone does not work sufficiently.
- Trial name
- NCT04521478
- Testing
- BI 1358894, Quetiapine
- Where
- 120 sites in United States, Argentina and 12 more
- Volunteers
- 389 people
- Sponsor
- Boehringer Ingelheim
Hepatic Impairment, Healthy, Hepatic Insufficiency
A Study to Learn How the Study Medicine Called Atirmociclib is Handled by the Body in People With Normal Liver Function and Different Levels of Liver Disease
The purpose of this study to understand how the study medicine atirmociclib behaves in the body and how safe it is for people with different levels of liver health.
- Conditions
- Hepatic Impairment, Healthy, Hepatic Insufficiency, Healthy Adults
- Trial name
- NCT07677358
- Testing
- Atirmociclib
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabetes Mellitus, Type 2
Research Study Comparing New Tablets of Semaglutide in New Doses, in Healthy People
In this study a known investigational medicinal product called semaglutide will be tested in four different tablet versions. In addition to semaglutide, the different tablet versions C, D, E and F contain different helping agents…
- Trial name
- NCT04524832
- Testing
- Oral semaglutide
- Where
- Germany
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
A Study in Healthy People to Test How 2 Different Formulations of a Combination Treatment (Vicadrostat and Empagliflozin) Are Taken up in the Body and How Food Influences the Amount of the Medicines in the Blood
To investigate the relative bioavailability of two different vicadrostat/empagliflozin combinations. Additionally, the trial investigates the effect of food on the pharmacokinetics of the vicadrostat/empagliflozin.
- Trial name
- NCT07133399
- Testing
- vicadrostat / empagliflozin combination 1, vicadrostat / empagliflozin 2
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Epilepsy
Utilizing Activity Trackers to Promote Physical Activity in People With Epilepsy: Can we Make a Difference?
The purpose of this study is to evaluate standard of care exercise education alone or in combination with a wearable physical activity tracker in people with epilepsy (PWE) to determine the most effective way to increase physical…
- Trial name
- NCT04357912
- Testing
- Activity Tracker Group, Standard of Care Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Individual Difference
Identifying Neuroimaging Biomarkers, Demographic, Personality and Sensory Factors for Predicting Extreme Pain Responses to Various Experimental Pain Stimulations in Healthy Subjects
The proneness to react to noxious stimuli varies widely between individuals and pain ratings of seemingly identical noxious stimuli may range from "no pain" to "excruciating pain" .
- Trial name
- NCT03436264
- Testing
- MRI
- Where
- Israel
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Healthy
A Study in Healthy People to Compare 3 Different Formulations of Apremilast Tablets Taken With or Without Food
The aim of this trial is to establish bioequivalence between EU-, US- and Japan-sourced Otezla® tablet formulations to assure comparability of results from Phase III trials of BI 730357 (new oral agent for treatment of psoriasis…
- Trial name
- NCT04811573
- Testing
- EU-sourced Otezla®, US-sourced Otezla®, Japan-sourced Otezla®
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pain, Recruitment
Effect of Different Techniques of Recovery in Para-athletes
Para-athletes are submitted and intense efforts in training and competitions that often overlap in days and weeks. In this sense, and in the search for better brands and indexes, it is necessary to use recovery methods that allow…
- Trial name
- NCT03431636
- Testing
- immersion, ice pack, rest
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Healthy Participants
Development of Assessment Method for Driving Ability Using Driving Simulator in Healthy Volunteers #2
The purpose of this study is to verify the intra-individual difference of the SDLP values in driving simulator.
- Trial name
- NCT03413592
- Testing
- Road-tracking test, Car-following test, Harsh-braking test
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Oral Health Knowledge, Oral Health Behavior Change
Improving Oral Health Knowledge and Habits in People With Diabetes Through a Theory Guided WhatsApp Education Program
The goal of this Educational interventional study is to test the usefulness of an educational program delivered through WhatsApp videos in increasing oral health knowledge and habits in people with Diabetes between the age of 18…
- Conditions
- Oral Health Knowledge, Oral Health Behavior Change, Diabetes Type 2
- Trial name
- NCT07323771
- Testing
- Health Belief Model (HBM) Based WhatsApp Oral Health Education Program, Educational Brochure Group
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Dow University of Health Sciences
Drug Addiction, Vulnerability to Substance Addiction
Individual Differences in Reward and Impulse Control
Background: The risk for becoming addicted to drugs varies among individual, even those using similar drugs in a similar way. It is not known why some people become addicted and others do not.
- Trial name
- NCT01621607
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cognitive Change
Executive Functions in Elite Athletes
In the study, it was aimed to compare the executive functions of elite athletes who do team sports and individual sports with each other and with individuals who do not do sports.
- Trial name
- NCT05488600
- Testing
- Executive Function Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital