Clinical trials: Individual Difference
Colorectal Carcinoma, Gastric Carcinoma
A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas
This study is open to adults with advanced cancer of the colon, rectum, stomach, or pancreas, that is the cancer cannot be removed by surgery or has spread.
- Conditions
- Colorectal Carcinoma, Gastric Carcinoma, Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT06882746
- Testing
- BI 765049
- Where
- 6 sites in United States, Germany and 1 more
- Volunteers
- 14 people
- Sponsor
- Boehringer Ingelheim
HIV Infections
Phase IV, a Clinical Trial to Assess Safety and Convenience of the Change From DTG/3TC to BIC/FTC/TAF in People With HIV, Good Virological Control and Neuropsychiatric Vulnerabilities
In people infected with HIV, with suppressed HIV viral load and receiving treatment with DTG/3TC: The change to BIC/FTC/TAF will decrease the development of adverse events of neuropsychiatric etiology.
- Trial name
- MIND (NCT05549180)
- Where
- 14 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Fundacion SEIMC-GESIDA
Acute Myeloid Leukemia
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
This phase II MyeloMATCH treatment trial studies how well ASTX727 and venetoclax plus enasidenib works compared to ASTX727 and venetoclax alone for the treatment of older patients with newly diagnosed acute myeloid leukemia (AML)…
- Trial name
- NCT06672146
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy
- Where
- 138 sites in United States, Puerto Rico
- Volunteers
- 93 people
- Sponsor
- National Cancer Institute (NCI)
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Psychotic Disorders
Improving Heart and Metabolic Health in People With Severe Mental Illness Through a Long-term Clinical Trial
Background Cardiometabolic conditions-including cardiovascular disease, type 2 diabetes, and obesity-are highly prevalent among individuals with psychotic disorders.
- Trial name
- LAGOM (NCT06781801)
- Testing
- Intervention
- Where
- 6 sites in Sweden
- Volunteers
- 650 people
- Sponsor
- Vastra Gotaland Region
Multiple Sclerosis
Lifestyle Physical Activity Intervention for Persons Newly Diagnosed With Multiple Sclerosis
The overall objective of the current study is to determine the efficacy of a 16-week remotely delivered lifestyle behavioral intervention compared with a control condition (i.e., waitlist control) in persons newly diagnosed with…
- Trial name
- NCT06355804
- Testing
- Physical activity condition, Waitlist condition
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Illinois Chicago
Parkinson Disease
Comparison of Health Care Delivery Methods in Parkinson's Disease
The goal of this observational study is to compare the ability to perform telemedicine visits at home, at a regional clinic close to home, and in-person in People with Parkinson's disease.
- Trial name
- NCT05725772
- Testing
- Location of Visit
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Investigating the Effects of Power Training in the Elderly
Effects of Different Power Training Intensities in Older Adults
Power (strength × velocity) is a crucial component for maintaining independence during aging. Therefore, investigating interventions aimed at improving this physical capacity is essential for this population.
- Trial name
- NCT07023146
- Testing
- Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ), low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
Impulsivity and Alcohol Response
Impulsivity, a well-known risk factor predicting negative outcomes, refers broadly to a proclivity towards rapid action with a suboptimal regard for future consequences.
- Trial name
- IDEA (NCT03736343)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pulmonary Disease, Chronic Obstructive
Internet-based Rehabilitation Aftercare Focusing on Physical Activity Promotion in Persons With COPD
The aim of the study is to evaluate a 12-week internet-based rehabilitation aftercare program with an emphasis on physical activity promotion for persons with COPD.
- Trial name
- COPD-AReNa (NCT05006560)
- Testing
- Pulmonary Rehabilitation (usual care), Pulmonary Rehabilitation (usual care) + familiarization with components of the aftercare program, After care: Exercise and physical activity promotion
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- University of Erlangen-Nürnberg
Obesity
Individual Differences in Children's Susceptibility to Overeating
The portion size of foods has been identified as an important determinant of energy intake in children. It remains to be determined to what extent child weight status and the relative reinforcing value of food may interact with…
- Trial name
- NCT01905293
- Testing
- Feeding Study
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Type 1
A Research Study of How Different Doses of a New Medicine NNC0148-0287 C (Insulin 287) Work on the Blood Sugar in People With Type 1 Diabetes When it is Taken Once a Week
This study compares the new long-acting insulin 287 with the marketed insulin glargine for use in type 1 diabetes. The study will test how insulin is taken up in your blood, how long it stays there and how the blood sugar is…
- Trial name
- NCT03723772
- Testing
- Insulin icodec, IGlar U100
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Novo Nordisk A/S
Parkinson Disease
Behavioural Change Techniques for Physical Activity and Exercise Adherence Among People With Parkinson's
Many people with Parkinson's (PwP) experience many barriers to reaching the recommended dosage of exercise. The aim of this study is to examine the feasibility of behavioural change support techniques delivered alongside an…
- Trial name
- PDActive (NCT06192628)
- Testing
- Parkinson's Exercise and Education Programme, Parkinson's Exercise and Education Programme and Behavioural Change
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University College Cork
Colour Perception, Color Perception
Visual Perception, Binocular Rivalry, and Fatigue-Related Individual Differences in Colour and Illumination Judgement
This observational study aims to characterise individual differences in colour perception and binocular rivalry. Participants will complete computer-based visual perception tasks, including a colour perception task and a…
- Conditions
- Colour Perception, Color Perception, Binocular Rivalry
- Trial name
- NCT07671144
- Testing
- Computer-Based Visual Perception Tasks
- Where
- 2 sites in Hong Kong
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
The purpose of this clinical trial is to find out whether one type of fish oil works better than another at improving metabolic health in people who are at high risk of developing type 2 diabetes.
- Conditions
- Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes / Type 2 Diabetes, Obesity & Overweight
- Trial name
- END-T2D (NCT07575438)
- Testing
- Fish Oil, Corn oil control
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Achilles Tendinopathy (AT), Musculoskeletal Diseases or Conditions
STICK2IT - Understanding Why People Do or Do Not Stick With Exercise Treatment for Achilles Tendinopathy
Achilles tendinopathy is a common condition that causes pain and stiffness in the tendon at the back of the ankle. It can make walking, exercise, work, and everyday activities difficult.
- Conditions
- Achilles Tendinopathy (AT), Musculoskeletal Diseases or Conditions, Adherence, Behaviour Change
- Trial name
- NCT07555184
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Multiple Sclerosis, Healthy Volunteer
Unraveling Active Ingredients of Neurorehabilitation: Investigating Cortical Activity During Task-oriented Exercises
The driving idea of this project is to use new imaging techniques during 0functional movements to study relearning during a typical rehabilitation session.
- Trial name
- INSIDE (NCT06826638)
- Where
- 3 sites in Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Liver Cirrhosis
A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis
This study is open to healthy adults and adults with liver cirrhosis. The purpose of this study is to compare how different medicines are handled by the body in people with and without liver cirrhosis.
- Trial name
- NCT05741385
- Testing
- Caffeine, Warfarin sodium, Omeprazole
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- Boehringer Ingelheim
Depressive Symptoms, Happiness
Believing People Can Change: A Randomized Controlled Trial of an Incremental Theory Intervention in Adolescence
This study will test the effectiveness of a brief educational intervention that teaches youth that they can grow and change, known as "growth mindset." Similar growth mindset interventions have improved youths' well-being and…
- Conditions
- Depressive Symptoms, Happiness, Life Satisfaction
- Trial name
- NCT04133389
- Testing
- Growth mindset of personality educational intervention, Growth mindset of athletic ability educational intervention
- Where
- Canada
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Guelph