Clinical trials: Individual Differences
Individuality, Perioperative/Postoperative Complications
Perioperative Heart Rate Variability Analysis in Realtime
This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent…
- Conditions
- Individuality, Perioperative/Postoperative Complications, Heart Rate and Rhythm Disorders, Surgical Complications From General Anesthesia
- Trial name
- PHERVR (NCT02761031)
- Where
- Austria
- Volunteers
- 88 people
- Sponsor
- Medical University of Vienna
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer
This study aims to learn more about symptoms that patients experience while receiving immunotherapy for cancer.
- Trial name
- NCT06562777
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- OHSU Knight Cancer Institute
Individuality, Asthma
Vaccination Response in Individual Monozygotic Twins
Respiratory viruses are known to be risk factors for asthma (e.g respiratory syncytial viruses, RSVs, and Human Rhinoviruses, HRVs, may induce bronchiolitis, and wheezing illnesses respectively).
- Conditions
- Individuality, Asthma, Immune System and Related Disorders
- Trial name
- NCT02296359
- Testing
- Influenza Vaccination
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Individual Difference
Evaluating Attitudes Towards Organ Donation in the United States on MTurk
The study is conducted to investigate the effects of priming different cultural orientations on participants' decisions on whether to donate their organs, in an opt-out donation system scenario where the default is a presumed…
- Trial name
- NCT04308746
- Testing
- Online Individualistic Prime (statement writing), Online Collectivistic Prime (statement writing)
- Where
- Singapore
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Sickness Behavior
Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences
The objective of the present study is to specifically assess the effect of lipopolysaccharide (LPS) administration on the development of behavioral symptoms and the underlying contribution of inflammatory processes.
- Trial name
- NCT02529592
- Testing
- Endotoxin
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder (ASD
Effectiveness of DIR/Floortime™ in Children With Autism Spectrum Disorder
This randomized controlled trial evaluates the efficacy of Integrated DIR/Floortime™ in improving functional emotional development and adaptive behavior in children aged 4-12 years with Autism Spectrum Disorder (ASD).
- Trial name
- DIR-ASD (NCT07758465)
- Testing
- DIR/Floortime, Standard therapy
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Fatima Tabassum
Inflammation Biomarkers, Inflammation
Individual Differences in Acute Response to Experimental Inflammation: Microcirculatory Changes and Psychological Predictors
The physiological and behavioral responses to inflammatory vary greatly between individuals. The knowlegde about what causes these differences is sparse but plausible explanations are variations in sensitivity to peripheral…
- Trial name
- NCT06618716
- Testing
- endotoxin escherichia coli (E. coli) lipopolysaccharide (LPS), Placcebo
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Individuality, Self-Efficacy
Effects of Individual and Group Occupational Therapy on General Self-Efficacy, Psychological Well-Being, Personal Independence and Occupational Therapy in Older Adults
The objective of this study is to determine whether individual and/or group occupational therapy leads to changes in generalized self-efficacy and psychological well-being, and to identify the type of therapy that has the best…
- Conditions
- Individuality, Self-Efficacy, Well-being
- Trial name
- NCT02906306
- Testing
- Individual Occupational Therapy, Group Occupational Therapy
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- University of Malaga
Postprandial Glucose Responses, Glucose Metabolism
The RepEAT Study: Individual Differences in Postprandial Glucose Responses and the Relation With Diet and Phenotype
Postprandial glucose responses are related to an increased risk of developing cardiometabolic diseases. Existing research recognizes the presence of inter-individual variation in postprandial glucose responses to the same meal or…
- Trial name
- RepEAT (NCT05456815)
- Testing
- Standardized diet
- Where
- Netherlands
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Circadian Rhythm, Time Perception
Circadian Timing and Time Perception in Healthy Adults
This study examines how a person's natural daily rhythm ("chronotype") affects the way time is experienced and judged. Healthy Danish-speaking adults (23-45 years) who are clearly morning-type or evening-type will complete two…
- Trial name
- ChronoTime (NCT07292597)
- Testing
- Session timing relative to chronotype
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Environmental Exposure, Individual Difference
Individual and Environmental Risk Factors for Unscheduled Hospitalizations of Elderly People
The elderly are weakened by the accumulation of chronic diseases. Their acute decompensation often leads to unscheduled hospitalization, which constitutes a breach of care with often serious consequences in terms of morbidity and…
- Trial name
- RIEHO-C (NCT04326556)
- Testing
- Prospective cohort for etiological and prognostic purposes
- Volunteers
- 70 people
- Sponsor
- Virginia BRANCO
Obesity
CD36 and Human Fat Taste Perception
The purpose of this study is to determine the effect of common human variants in in taste related genes, such as CD36 gene, a putative fat taste receptor, affect fat taste perception.
- Trial name
- FATYP (NCT02699567)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Coronary Heart Disease
Multi-omics Study of Clinical Endpoints in CHD
This study aimed to explore underlying mechanisms of individual differences in drugs for coronary heart disease treatment and its association with adverse consequences.
- Trial name
- OmiDETCHD (NCT03797339)
- Testing
- risk factors of adverse cardiovascular events, multi-omics target discovery, validation
- Where
- 5 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Amputation, Amputation, Traumatic
Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control
The goal of this clinical trial is to systematically evaluate whether or not two commonly held fundamental assumptions for pattern recognition control translates to functional performance when tested on individuals aged 18 years…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User
- Trial name
- NCT07011420
- Testing
- Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Liberating Technologies, Inc.
Healthy Adult Participants
Alcohol Sensitivity Among Older Adults Who Consume Alcohol
This is a proof-of-concept study exploring individual differences in sensitivity to alcohol among older healthy current drinkers aged 65 to 80.
- Trial name
- NCT07636447
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Florida
Knee Osteoarthritis (OA), Chronic Pain
Individual Differences in Gait and Osteoarthritis Pain
The goal of this observational study is to look at inter-individual differences in knee osteoarthritis (OA) walking pain and performance.
- Conditions
- Knee Osteoarthritis (OA), Chronic Pain, Chronic Knee Pain
- Trial name
- INDIGO (NCT07308873)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Healthy
Individual Differences in the Response to Drugs
The purpose of this study is to examine whether individual differences in acute responses to drugs co-vary across three drugs from different drug classes: alcohol, amphetamine and delta-9-tetrahydrocannabinol (THC).
- Trial name
- TDS (NCT02485158)
- Testing
- THC, AMP, ALC
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Individuality, Narrative Medicine
PopPK Profile of Qishe Pill: Study Protocol for a Phase I Clinical Trial
Qishe Pill (Shanghai Sundise Traditional Chinese Medicine Co., Ltd, China), composed of processed Radix Astragali, Muscone, Szechuan Lovage Rhizome, Radix Stephaniae Tetrandrae, Ovientvine, and Calculus Bovis Artifactus, has been…
- Trial name
- NCT02294448
- Testing
- Qishe Pill
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine