Clinical trials: Indocyanine Green (ICG)
Head and Neck Cancer
NIR Fluorescence Imaging During Neck Dissection in Head and Neck Cancer Patients After iv Injection of ICG
The purpose of this study is to determine if NIR fluorescent imaging is an effective approach to detect the margins of head and neck tumours or lymph nodes draining the tumour
- Trial name
- NCT02027831
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Jules Bordet Institute
Perfusion, Fluorescence Imaging
Micro-dosing Indocyanine Green (ICG) in Children
The goal of this cohort study is to identify the lowest dose of Indocyanine Green (ICG) that achieves satisfactory intra-operative fluorescence for the assessment of gastrointestinal or genitourinary tract perfusion in children.
- Conditions
- Perfusion, Fluorescence Imaging, Gastrointestinal Tract Disorders, Genitourinary Disease
- Trial name
- NCT06421103
- Testing
- Indocyanine Green (ICG)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Liver Carcinoma
Radiofrequency-responsive Layered Double Hydroxides for Enhanced Arterial Embolization and Thermal Immunotherapy in Hepatocellular Carcinoma
Liver cancer is one of the most common malignant tumors and the third leading cause of cancer-related deaths globally. Recent epidemiological studies show that in China, liver cancer ranks fourth in incidence and second in…
- Trial name
- NCT06966986
- Where
- China
- Volunteers
- 130 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Pediatric Renal Tumor, Metastatic Osteosarcoma
Indo-cyanine Green (ICG) in Paediatric Oncology MIS
Indo-cyanine green (ICG) is a dye that has been used for a variety of adult and paediatric uses since 1956. Over the past few years, near infrared (NIRF) technology has been developed which allow is use as a fluorescence agent…
- Conditions
- Pediatric Renal Tumor, Metastatic Osteosarcoma, Metastatic Ewing Sarcoma, Pulmonary Metastasis
- Trial name
- NCT04854018
- Testing
- Indocyanine green
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Prostate Cancer, Lymph Node Metastases
Use of Indocyanine Green During Pelvic Lymph Node Dissection in Prostate Cancer.
Standard treatment of local or locally advanced prostate cancer is radical prostatectomy (RRP) surgery. During RRP in certain patients extended lymph node dissection (ELND) is recommended.
- Trial name
- NCT04882618
- Testing
- Indocyanine green
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Breast Neoplasms
ICG and Blue Dye Guided Sentinel Lymph Node Biopsy in Patients Underwent Neoadjuvant Therapy
The value of sentinel lymph node biopsy (SLNB) in patients underwent neoadjuvant chemotherapy is controversial. Lower detection rate and higher false negative rate are the main problem.
- Trial name
- NCT02869815
- Testing
- ICG+Methylene Blue
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University People's Hospital
Colon Cancer, Lymphatic Metastasis
Sentinel Node Mapping With Indocyanine Green in Colon Cancer: a Feasibility Trial and a Descriptive Serie.
This study is a clinical feasibility trial that will contribute to the clarification of whether sentinel node mapping with indocyanine green (ICG) provides a better basis for staging of colorectal cancer.
- Trial name
- SENSE (NCT02167087)
- Testing
- Sentinel node mapping
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Ismail Gögenür
Colon Carcinoma, Lymph Node Metastases
Lymph Node Mapping Via Flourescent Dye in Colon Cancer
The aim of the study is to evaluate whether lymph nodes draining the region of the carcinoma are located only inside the lines of standard resection or in some percentages are located outside as well.
- Trial name
- NCT04959604
- Testing
- ICG-marking endoscopically
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Breast Cancer
Evaluation of Two Techniques for the SLN Detection in BC Patients
The revision of our data shows that since its introduction in our institution (Jules Bordet Institute) in 1998 (until 2010, the year of the last review of cases), 53 patients underwent neoadjuvant therapy before selective…
- Trial name
- NCT02032498
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 214 people
- Sponsor
- Jules Bordet Institute
Head and Neck Cancer
Intraoperative Evaluation Using ICG and SPY Fluorescence to Prevent Wound Complications in Head and Neck Surgery.
Wound complications, such as salivary-cutaneous fistulas and skin necrosis, result in significant patient morbidity and death. Head and neck wounds are complicated because of multiple tissue layers, critical structures and…
- Trial name
- NCT03345732
- Testing
- ICG and SPY system for wound complications
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Breast Cancer
Clinical Application of Near-infrared Fluorescence Guided Localization on Breast Surgery in Breast Cancer
Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has been used for breast cancer surgery such as sentinel lymph node (SLN) mapping and breast cancer localization.
- Trial name
- NCT02473159
- Testing
- indocyanine green
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- National Cancer Center, Korea
Skull Base Neoplasms
ICG Use in Angiography for Nasoseptal Flap Harvest
This is a feasibility study in which indocyanine green (ICG) will be administered during routine expanded endonasal approach (EEA) for cranial base pathologies in which a nasoseptal flap harvest will be necessary.
- Trial name
- ICG (NCT02117310)
- Testing
- indocyanine green
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Ohio State University
Achalasia, Esophageal, Achalasia
The Use of Indocyanine Green Fluorescence (ICG) During Laparoscopic Heller- Dor
The aim this prospective observational study is to evaluate the role of Indocyanine Green Fluorescence (ICG) in patients with achalasia underwent to Heller-Dor laparoscopic.
- Conditions
- Achalasia, Esophageal, Achalasia, Indocyanine Green (ICG), Indocyanine Green
- Trial name
- NCT07181070
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Federico II University
Chronic Calculous Cholecystitis, Laparoscopic Cholecystectomy
Using Indocyanine Green (ICG) to Outline Biliary Tree During Laparoscopic Cholecystectomy
The current study shows that Indocyanine green (ICG)-fluorescence cholangiography can be useful in identifying the extrahepatic biliary anatomy during Calot's triangle dissection.
- Trial name
- ICG (NCT06629415)
- Testing
- Indocyanine Green, Indocyanine Green Drug
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Theodor Bilharz Research Institute
Breast Cancer
Evaluate the Implementation of Using Indocyanine Green for Sentinel Lymph Node Mapping in Breast Cancer Patients
This single-institution pilot study uses a pre- and post-implementation design to evaluate the implementation of ICG fluorescent imaging for sentinel lymph node biopsy (SLNB) in an Italian hospital.
- Trial name
- INFLUENCE II (NCT07441733)
- Testing
- ICG used as a tracer for sentinel lymph node, technetium 99 used as a tracer for sentinel lymph node
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Rectal Cancer, Total Mesorectal Excision
Examination of Rectal Blood Supply During Rectal Cancer Surgery Using Laser Speckle Contrast Imaging
This multicentre feasibility study evaluates the feasibility of performing laparoscopic Laser Speckle Contrast Imaging (LSCI) measurements of rectal perfusion during rectal cancer surgery.
- Conditions
- Rectal Cancer, Total Mesorectal Excision, Laser Speckle Contrast Imaging, Indocyanine Green (ICG)
- Trial name
- LIRA (NCT07799740)
- Testing
- Laser speckle contrast imaging
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Reconstructive Surgical Procedures, Plastic Surgery
Leica Microsystems Sponsored Study to Collect and Confirm Clinical Data on the Performance of the GLOW800 Device When Used in Accordance With Its Intended Use.
This post-market clinical follow-up (PMCF) study aims to confirm the safety and performance of the GLOW800 surgical microscope accessory when used in conjunction with the ARveo8x surgical microscope.
- Conditions
- Reconstructive Surgical Procedures, Plastic Surgery, Vascular Surgical Procedure, Cerebrovascular Disorder
- Trial name
- IMED-GLOW800 (NCT07164040)
- Testing
- The GLOW800, a non-contact, non-invasive device, allows the surgical microscope ARveo 8 and ARveo 8X to produce excitation light and resolve fluorescence emission from the fluorescent agent ICG
- Where
- 3 sites in Portugal, Spain and 1 more
- Volunteers
- 31 people
- Sponsor
- Leica Microsystems (Schweiz) AG
Lymphedema
The Use of Non-ICG-Enhanced Lymphatic Vessels for LVA
The aim of the present study was to investigate the impact of non-ICG(+) LVs on the outcomes after LVA compared to ICG(+) LVs with propensity-score-match analysis.
- Trial name
- ICG LVA (NCT06742242)
- Testing
- lymphaticovenous anastomosis
- Where
- Taiwan
- Volunteers
- 106 people
- Sponsor
- Chang Gung Memorial Hospital
Stage III Periodontitis
Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management
To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels.
- Trial name
- NCT07316023
- Testing
- Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded nanoparticles, Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded macroparticles, Non- surgical periodontal therapy only
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Nada Mahmoud Soliman
Breast Cancer
Fluorescent Dyes for Lymph Node Mapping
The goal of this clinical research study is to find lymph nodes before surgery using a dye called indocyanine green (IC-Green). Objectives: 1.
- Trial name
- NCT01095913
- Testing
- Indocyanine green (ICG)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center