Clinical trials: Induction Therapy
Healthy Volunteers
A Study of LY2835219 in Healthy Participants
The aim of this two-period study is to compare how much of the study drug gets into the blood stream when it is given as a single oral dose and when it is given as a single oral dose in combination with rifampin (a Food and Drug…
- Trial name
- NCT02256267
- Testing
- LY2835219, Rifampin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Alzheimer Disease, Cognitive Decline
40 Hz Transcranial Alternating Current Stimulation for Inducing Gamma Oscillations
This study aims to compare the efficacy of different 40 Hz tACS protocols in entraining gamma oscillations, which are linked to various cognitive functions and play a significant role in cognitive impairments like Alzheimer's…
- Trial name
- NCT06740864
- Testing
- Transcranial alternating current stimulation
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Opioid Use Disorder, Chronic Back Pain
Focused Ultrasound for the Complex Patient
The goal of this clinical trial is to to inhibit the anterior insula (AI) with low intensity focused ultrasound (LIFU) to determine the causal role for the AI in pain processing, anxiety, and opiate cue-induced craving.
- Conditions
- Opioid Use Disorder, Chronic Back Pain, Anxiety
- Trial name
- LIFU (NCT06453109)
- Testing
- low intensity focused ultrasound (LIFU)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Washington D.C. Veterans Affairs Medical Center
Pharmacodynamic Interaction
Pharmacodynamic Interactions of Propofol and Dexmedetomidine on Intravenous Anesthesia
The purpose of this study is to determine pharmacodynamic interactions of propofol and dexmedetomidine,exploring the effect of dexmedetomidine on propofol unconsciousness median effective concentration (EC50).
- Trial name
- PIPDIA (NCT02777619)
- Testing
- 0.0ng/ml Dexmedetomidine, 0.4ng/ml Dexmedetomidine, 0.6ng/ml Dexmedetomidine
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Labor, Induced, Induced; Birth
Effect of Acidic Vaginal pH on the Efficacy of Dinoprostone for Labor Induction
Acidification of vaginal pH has been proposed as a potential factor that could help increase the efficacy of vaginal prostaglandins in labor induction.
- Trial name
- NCT05100264
- Testing
- Vaginal washing with 5% acetic acid, Vaginal washing with 0.9% NS
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
Substance Use Disorder, Delinquency
Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study
The purpose of this study is to evaluate two brief, sustainable interventions for a sample of 280 adolescents charged with an initial drug-related offense: Motivational Enhancement Therapy (MET) intervention for youth and the…
- Trial name
- MAST1 (NCT01616212)
- Testing
- Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Labor Induction
Observatory on Artificial Labour-induction Methods and Measuring Immediate Postpartum Maternal Satisfaction
Our hypothesis is that there is one sequence of labour-induction that leads to a better experience of childbirth than others. This is based on the following underlying theories : Maternal satisfaction depends on the number of…
- Trial name
- SATISFACC (NCT04075630)
- Where
- 2 sites in France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Substance Abuse, Families
Family-Based Drug Services for Young Disaster Victims
This protocol seizes this rare scientific opportunity to test an integrative family based model to address youths' coexisting substance abuse and trauma in the wake of Hurricane Katrina.
- Conditions
- Substance Abuse, Families, Trauma
- Trial name
- Katrina (NCT01859000)
- Testing
- Multidimensional Family Therapy, Group CBT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Miami
Alexithymia, Alcohol Use Disorder
Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder
Art therapy support combined with standard care for people with an alcohol use disorder coming to a day hospital for withdrawal could be beneficial compared to standard care alone because it would improve the alexithymia of these…
- Trial name
- ALEXART (NCT04206930)
- Testing
- Art Therapy
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Postpartum Hemorrhage
In Vitro Optimization of Oxytocin-induced Myometrial Contractility by Propranolol
The rates of cesarean deliveries (CD) and postpartum hemorrhage (PPH) are on the rise, with failed induction and augmentation of labor as major contributing factors.
- Trial name
- NCT03434444
- Testing
- Oxytocin, Propranolol
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Opioid Withdrawal, Postoperative Pain
Opioid Tapering After Spine Surgery
The effect of a tapering plan combined with telephone counselling to assist patients in opioid tapering after surgery remains unexplored.
- Trial name
- NCT04140955
- Testing
- Tapering plan and telephone counselling
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Inflammatory Bowel Diseases
Response To Medical Therapy in Inflammatory Bowel Disease Patients Carrying-out a Prescribed Exercise Programme
The investigators propose the use of a 20 week physician-derived exercise programme will lead to an improvement in physical fitness which will in turn lead to an increase in muscle mass, a reduction in visceral obesity resulting…
- Trial name
- NCT05174754
- Testing
- Physician-prescribed Exercise Programme, Best Medical Therapy
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Induction of Labor in Multiparous Women
A Study Comparing Vaginal Misoprostol and Intravenous Oxytocin for Induction of Labor
This study will compare the effectiveness of vaginal misoprostol (Cytotec) and intravenous oxytocin (Pitocin) in multiparous women who present at term for labor induction.
- Trial name
- NCT01634854
- Testing
- Vaginal Misoprostol, Intravenous Oxytocin
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Emergence Agitation
Effect of Induction Method in Post Operative Agitation
To compare the effect of two different induction method; mask ventilation and intravenous cannulation on emergence agitation on pediatric adenotonsillectomy
- Trial name
- NCT03252405
- Testing
- mask ventilation, intravenous cannulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Opioid-Related Disorders
Bioequivalency Study of Buprenorphine Hydrochloride 8 mg Tablet Under Fasted Conditions
The objective of this study was to prove the bioequivalence of Buprenorphine HCl 8 mg tablet under fasted conditions.
- Trial name
- NCT00992095
- Testing
- buprenorphine hydrochloride
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Induction of Labor Affected Fetus / Newborn
Propranolol and Misoprostol Versus Misoprostol Alone for Induction of Labor in Primigravidas
To compare propranolol and misoprostol versus misoprostol alone for induction of labour in primigravidas
- Trial name
- NCT04533841
- Testing
- Misoprostol, Propranolol
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ahmed mohamed fathy ismail
Pre-induction Cervical Ripening
Comparing 30mL Single Versus 80mL Double Balloon Catheters for Pre-induction Cervical Ripening
The purpose of this study is to perform a randomized controlled trial to compare the efficacy of 80mL double balloon catheter versus a 30mL single catheter balloon for pre-induction cervical ripening by evaluating the change in…
- Trial name
- NCT02344459
- Testing
- mechanical pre-induction cervical ripening
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Dependence, Alcohol Abuse
Community Reinforcement and Family Training (CRAFT) for Treatment-resistant Individuals With Alcohol Use Disorders
The present study examines the efficacy of the Community Reinforcement and Family Training (CRAFT) for Concerned Significant Others (CSOs) of individuals with alcohol use disorders (AUDs) using a randomized waiting list (WL)…
- Trial name
- CRAFT (NCT02112396)
- Testing
- Community Reinforcement and Family Training
- Where
- Germany
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Luebeck
Headache, Migraine
The Effect of Adenosine on Cranial Hemodynamic, Headache and Migraine Induction Properties.
Adenosine is a nucleoside that plays a role in both vascular and nociceptive systems, and it has been proposed that adenosine may cause headache in particularly sensitive subjects.
- Trial name
- NCT04577443
- Testing
- Adenosine, Saline
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Opioid-use Disorder
Tailoring a Mindful Intervention to Enhance Opioid Treatment
The main aim of this study is to better understand whether yoga can be blended with mindfulness as an additional intervention for people receiving medication assisted treatment at a Hartford-based community agency.
- Trial name
- BEING (NCT04879238)
- Testing
- BEING
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
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