Clinical trials: Induction of Anesthesia
Neuromuscular Blockade, Neuromuscular Blockade, Residual
Three Different Doses of Neostigmine on the Reversal of Cisatracurium-induced Moderate Neuromuscular Blockade
The aim of the present study will be to evaluate by means of a prospective randomized clinical trial, the time required for the reversal of moderate neuromuscular blockade (NMB) (Train-of-four count = 3; TOFc 3) to Train-of-four…
- Trial name
- NCT05037006
- Testing
- Sevoflurane - Neostigmine 30, Sevoflurane - Neostigmine 50, Sevoflurane - Neostigmine 70
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Post Induction Hypotension
Dose Responsive Study of Ringer's Lactate Solution in Prevention of Post-induction Hypotension
To assess the dose responsiveness of ringer lactate solution in prevention of post-induction hypotension predicted by Ultrasound guided Inferior Vena Cava diameter in patients receiving General anesthesia.
- Trial name
- NCT05924230
- Testing
- RL 10ml/kg, RL 15ml/kg
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tata Main Hospital
General Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia
To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection…
- Trial name
- NCT05478174
- Testing
- HSK3486, Propofol
- Where
- 23 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Hypotension on Induction
Pre-operative Ultrasonographic Evaluation of Caval Aorta Diameter Index as a Predictor for Post-induction Hypotension
Comparison between ultrasound measurement of IVCD-AOd index in prediction of post induction hypo tension
- Trial name
- NCT04658576
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia
Duration and Depth of Anesthesia Induced by a Bolus of Etomidate
Induction of general anesthesia requires to be safe and to ensure a proper level of anesthesia. A proper anesthesia is sufficient to guarantee loss of consciousness and amnesia and without being too depth leading to a…
- Trial name
- NCT05862753
- Testing
- induction by Etomidate bolus
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Blood Pressure
Correlation Between Dorsalis Pedis and Radial Arterial Invasive Blood Pressures During Anesthesia Induction in Neurosurgical Patients
Anesthesiologists need to understand the specific difference between dorsalis pedis arterial(DPA) pressure and the more commonly used radial arterial(RA) pressure When blood pressure monitoring at DPA.
- Trial name
- NCT04469751
- Testing
- invasive blood pressure monitoring
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Vascular Stiffness, Hypotension on Induction
The Relationship Between BCM, Arterial Stiffness and Hemodynamic Instability During Induction of General Anesthesia
Arterial hypotension during induction of general anesthesia is a risk factor for developing postoperative cardiovascular complications.
- Conditions
- Vascular Stiffness, Hypotension on Induction, Anesthesia; Reaction
- Trial name
- NCT03237429
- Testing
- bioimpedance spectroscopy
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Lower Esophageal Sphincter
The Effect of an Opioid on the Lower Esophageal Sphincter During Anesthesia Induction
This study evaluates the effects of adding an opioid (alfentanil) during anesthesia induction with respect to the barrierpressure in the esophagogastric junction.
- Trial name
- NCT01199458
- Testing
- alfentanil, saline
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
This Study Was Focused to Evaluate Feasibility of Doppler Tissue Monitoring During the Induction Anesthesia,, and Evaluate Routine Propofol Induction's Effect on Myocardial Tissue Motion, Using Non-invasive Doppler Tissue and 2D Speckle Tracking Imaging.
Propofol Induction's Effect on Cardiac Function
Background: Propofol effects dose-dependent myocardial depression, but there is little clinical data available regarding the direct impact of propofol induction on myocardial function.
- Conditions
- This Study Was Focused to Evaluate Feasibility of Doppler Tissue Monitoring During the Induction Anesthesia,, and Evaluate Routine Propofol Induction's Effect on Myocardial Tissue Motion, Using Non-invasive Doppler Tissue and 2D Speckle Tracking Imaging., This is the First Study, to Our Knowledge, Which Has Evaluated the Possible Impact of Propofol Induction on LV Function.
- Trial name
- NCT02408341
- Where
- South Korea
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Gender, Anesthesia
Dosage of Propofol Based on Lean Body Weight
Patients who will be anesthesia induced with propofol will be body analyzed with Tanita before the operation. Height, weight, age, gender and other general information of the patients will be recorded.
- Trial name
- NCT06018623
- Testing
- It is an observational study and no non-routine procedures will be performed on patients. Routine anesthesia procedure will be applied to the patients
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Urologic Diseases
Effect of Prewarming During Induction of General Anesthesia Combined With Warmed Intravenous Fluid on Core Temperature.
Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming during induction of general anesthesia during urologic surgery.
- Trial name
- NCT05636189
- Testing
- warming during induction of anesthesia, Prewarmed intravenous fluid administration
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Inje University
Obstructive Sleep Apnea
Mask Study: One-handed vs. Two Handed Technique in Children
During induction of anesthesia in children, the investigators have observed significant variability in mask holding technique at our institution among different anesthesia practitioners.
- Trial name
- NCT03215121
- Testing
- One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.
Many previous studies have investigated the ability of various methods such as passive leg raising test , and inferior vena cava collapsibility index in predicting post-spinal hypotension, but none of them have succeeded in…
- Trial name
- NCT05991063
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ventilation
Manual Ventilation Versus Pressure Controlled Mechanical Ventilation in Children
The investigator will compare the feasibility of manual ventilation and pressure-controlled mechanical ventilation during facemask ventilation in children.
- Trial name
- NCT02751047
- Testing
- manual ventilation, Pressure controlled mechanical ventilation
- Where
- South Korea
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Anesthesia, General
Reduction of Rocuronium-induced Injection Pain With Aspiration of Blood
The goal of this clinical trial is to learn about reduction of rocuronium injection pain in participants receiving general anesthesia.
- Trial name
- NCT06150001
- Testing
- rocuronium-normal-saline mixture, rocuronium-lidocaine mixture, rocuronium-blood mixture
- Where
- Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Air Insufflation, Regurgitation
Risk of Gastric Insufflation Related to Facemask Ventilation Technique During Anaesthetic Induction, With or Without PEEP
Continuous positive pressure during anesthetic induction is today not routinely used partly a to the risk of gastric insufflation because of higher ventilatory pressures.
- Trial name
- NCT02238691
- Testing
- Mask ventilation with PEEP via a face mask device
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center