Clinical trials: Induction of Labor
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Induction of Labor
Induction of Labor by Oral Misoprostol Solution
AIM: To evaluate effectiveness and safety of titrated oral misoprostol solution (OMS) in comparison with static-dose oral misoprostol solution for induction of labor at term.
- Trial name
- OMS (NCT04891679)
- Testing
- Oral misoprostol solution (OMS)
- Where
- India
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Labor Onset and Length Abnormalities
Effect Mobility During Induction of Labor on Time to Delivery. A Randomized Controlled Trial
this is a andomized controlled trial the evaluates the effect of enhanced mobility, controlled via electronic pedometers, during induction of labor by extra amniotic balloon on time to delivery.
- Trial name
- NCT03784092
- Testing
- feedback
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Intemittant, Continue, Oxytocin
Continuous Versus Intermittent Oxytocin for Induction of Labor: A Randomized Study
This study evaluates continuous oxytocin versus intermittent oxytocin for induction of labor at term. Half of participants will be taken continuous oxytocin, while the other half will be taken intermittent oxytocin.
- Trial name
- NCT02859571
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Cannabis Use Disorder, Cannabis Dependence
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
This study investigates the effects of repeated NAC administration on glutamate concentrations in the anterior cingulate cortex (ACC), on neurocognitive functioning, and on neuro-inflammatory parameters in adult…
- Trial name
- NCT03221231
- Testing
- N-acetylcysteine, Magnetic Resonance Imaging, Neurocognitive measures
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Induced Vaginal Delivery
Newborn Pain and Stress Levels in Oxytocin Induction at Birth
The aim of the study is to compare pain and stress levels in the early neonatal period in newborns with and without oxytocin induction. The research was conducted in a case-control study design.
- Trial name
- NCT06474000
- Testing
- Oxytocin induction group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Premature Birth, Obstructive Lung Disease
Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood
Preterm birth alters the normal sequence of lung development with lasting respiratory consequences. It is still unclear whether observed respiratory morbidities in preterm born individuals reflect sequelae from a non-progressive…
- Conditions
- Premature Birth, Obstructive Lung Disease, Bronchopulmonary Dysplasia
- Trial name
- NCT02820818
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Poor; Labor
The Effect of Coadministration of Oral Propranolol to Oxytocin on Induction of Labor
The effect of coadministration of oral propranolol to oxytocin on induction of labor.
- Trial name
- NCT02702674
- Testing
- propranolol, Oxytocin
- Where
- Egypt
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Obstetric Labour, Premature
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Retosiban (GSK221149) When Dosed With Efavirenz (EFZ)
This will be a randomized single sequence open label study. This study is designed to determine if chronic dosing with efavirenz (EFZ) will have an effect on the pharmacokinetics (PK) of intravenously-administered retosiban in…
- Trial name
- NCT01867996
- Testing
- Retosiban, EFZ 600 mg
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Premature Rupture of Membranes
FOLCROM Trial: Foley Catheter in Rupture of Membranes
Multicenter randomized clinical trial comparing oxytocin versus oxytocin and foley catheter for induction in women who present with premature rupture of membranes who are not in labor.
- Trial name
- FOLCROM (NCT01973036)
- Testing
- Foley Catheter, Oxytocin
- Where
- 5 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Induction of Labor
Cervical Ripening Balloon for 12 Hours vs. 1 Hour.
The aim of this study is a comparison of induction of labor with a cervical ripening balloon left in place for one hour compared to twelve hours. The primary outcome is time to delivery.
- Trial name
- NCT05922111
- Testing
- cervical ripening balloon for one hour, cervical ripening balloon for twelve hours
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Labor Onset and Length Abnormalities, Induced; Birth
Comparison of Misoprostol Ripening Efficacy With Dilapan
The purpose of this study is to find out if Dilapan works as well as Misoprostol for preparing the mouth of the uterus (cervix) for inducing labor in women who need to undergo this procedure.
- Trial name
- COMRED (NCT03670836)
- Testing
- Dilapan, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Columbia University
BPD - Bronchopulmonary Dysplasia, VLBW - Very Low Birth Weight Infant
Duodenal Feeds in Very Low Birth Weight Infants
Premature infants have high rates of bronchopulmonary dysplasia (BPD) due to prematurity of the participants' lungs and the need for prolonged respiratory support.
- Conditions
- BPD - Bronchopulmonary Dysplasia, VLBW - Very Low Birth Weight Infant, Feeding Disorder Neonatal, Feeding; Difficult, Newborn
- Trial name
- NCT04246333
- Testing
- Mode of Delivery of Feeds
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Cervical Ripening
Induction of Labor in Oligohydramnios
When oligohydramnion - decreased amniotic fluid, is diagnosed at term pregnancies, the common practice is to induce labor. Whenever the cervix is not ripened, there are several methods to ripen the cervix, two of which are…
- Trial name
- NCT00815542
- Testing
- double balloon catheter, prostaglandins E2
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Induced Labor, Cervical Ripening
Low-dose Vaginal Misoprostol Versus Vaginal Dinoprostone Insert for Induction of Labor
Purpose: To compare the efficacy and safety of low-dose protocol of vaginal misoprostol and vaginal dinoprostone insert for induction of labor in women with post-term pregnancies.
- Conditions
- Induced Labor, Cervical Ripening, Obstetric Labor, Pregnancy
- Trial name
- MADUTER (NCT03744364)
- Testing
- Misoprostol 25 mcg, Dinoprostone 10mg
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Induction of Labor
Foley Labor Induction Trial at Term and in PROM
This study is considering current standard oxytocin dosing regimen in combination with Foley bulb for cervical ripening is associated with improved outcomes including greater percentage of women delivered within or less than 24…
- Trial name
- NCT02098421
- Testing
- Oxytocin
- Where
- 2 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Induction of Labor, Cesarean
A Prospective Comparative Study of Induction of Labor With a Cervical Ripening Double Balloon vs Foley Catheter
Hypothesis: The induction of labor in patients with unfavorable Bishop score is a challenging obstetrical process, and may be influenced or complicated by the cervical ripening method used.
- Conditions
- Induction of Labor, Cesarean, Endometritis
- Trial name
- NCT00501033
- Testing
- Mechanical induction of labor, Double Balloon, Foley Catheter
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Obesity, Induction of Labor Affected Fetus / Newborn
Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity increases the risk of pregnancy complications, including among others puerperal infections and cesarean delivery, and risk rises with increasing body mass index (BMI).
- Trial name
- APPOINT (NCT03801252)
- Testing
- Cefazolin, Azithromycin
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Labor Induction
A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death
Misoprostol (Cytotec®) is a synthetic prostaglandin E1 analog that has been marketed in the United States since 1988 as a gastric cytoprotective agent.
- Trial name
- NCT00141895
- Testing
- Misoprostol
- Where
- Lebanon
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center