Clinical trials: Infant Obesity
Prader-Willi Syndrome
PWS European Blood Bank for Infants and Controls From 0 to 48 Months
The present project aims to determine the underlying mechanisms for the switch from failure to thrive to excessive weight gain and hyperphagia with impaired satiety in PWS.
- Trial name
- NCT02529085
- Testing
- blood samples
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
HIV, Obesity
Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir
A total of 1900 pregnant women in the 1st trimester and their children will be enrolled and followed for two years (ORCHID study main cohort).
- Conditions
- HIV, Obesity, Obesity, Infant, Maternal Obesity During Childbirth
- Trial name
- ORCHID (NCT04991402)
- Testing
- Dolutegravir-based antiretroviral therapy
- Where
- 2 sites in South Africa
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Columbia University
Adolescent Mothers, Infant Obesity
Tools For Teen Moms: Reducing Infant Obesity Risk
The purpose of this social media group randomized trial (GRT) is to test the feasibility of our Baby Dayr for Teen Moms intervention to increase maternal responsiveness to infant cues and implement healthy feeding practices…
- Trial name
- TFTM (NCT02244424)
- Testing
- Tools for Teen Moms
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Michigan State University
Infant Development
Effect of a New Infant Cereal on Weight Gain
The purpose of this study is to determine whether a new infant cereal has an effect on weight gain and intestinal microbiota compared to a standard cereal in healthy infants .
- Trial name
- CEOBE (NCT02165956)
- Testing
- New Infant Cereal, Standard Infant Cereal
- Where
- 5 sites in Spain
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Laboratorios Ordesa
Growth, Infant Development
The Effect of Baby-Led Weaning and Traditional Complementary Feeding Education on Infant Development
The goal of this [type of study: clinical trial] is to compare compare the nutrition, development, obesity risk and anemia risk of the infant with the BLW method and TCF method given to the mothers of infants who have switched to…
- Conditions
- Growth, Infant Development, Complementary Feeding, Nutrition, Healthy
- Trial name
- NCT05771324
- Testing
- Baby-Led Weaning (BLW), Traditional Complementary Feeding (TCF)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Full Term Infants, Environmental Exposures
Epigenetic and Developmental Effects of In Utero Exposure to Environmental Toxicants
Metabolic diseases such as obesity and diabetes are modern day epidemics. Early life exposure to an adverse developmental environment, including environmental toxins, are linked to increased susceptibility to obesity, metabolic…
- Conditions
- Full Term Infants, Environmental Exposures, Adiposity
- Trial name
- NCT01815385
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Overweight, Obesity
Iron Absorption and Transfer to the Fetus During Pregnancy in Normal Weight and Overweight/Obese Women and the Effects on Infants Iron Status
Overweight and obesity causes low-grade systemic inflammation, which sharply increases risk for iron deficiency. Studies in our laboratory have shown that this is mainly the result of reduced dietary iron absorption because of…
- Conditions
- Overweight, Obesity, Pregnancy
- Trial name
- PIANO (NCT02747316)
- Testing
- Stable iron isotope 57 (57Fe) labeled iron solution, Stable iron isotope 58 (58Fe) labeled iron solution
- Where
- Switzerland
- Volunteers
- 83 people
- Sponsor
- Swiss Federal Institute of Technology
Gestational Diabetes, Obesity
Healthy Diet for Healthy Moms and Babies
The purpose of this clinical study is to collect baseline information on dietary habits and metabolic risk factors, and to examine the effects of a dietary intervention focusing on fiber and antioxidant rich berries on the…
- Conditions
- Gestational Diabetes, Obesity, Pregnancy, High Risk
- Trial name
- NCT03467503
- Testing
- Blueberry + soluble fiber
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Obesity, Metabolic Syndrome
Is Fructose Linked to Adiposity in Babies?
The obesity epidemic has reached down into the infant and toddler age group. Dietary indiscretion during pregnancy, particularly in our current food environment, is a major risk factor for both gestational diabetes and neonatal…
- Trial name
- FLAB (NCT01262781)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity, Infant Obesity
Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months
This study aims to assess the impact of a home-visiting program, called "Family Spirit Nurture" (FSN), on reducing early childhood obesity in American Indian (AI) children.
- Conditions
- Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits
- Trial name
- NCT03334266
- Testing
- Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC)
- Where
- 3 sites in United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Childhood Obesity
The Bottle Optimization Testing Tiny Little Eaters Study
The researchers will study how babies respond to bottle nipples with different flow rates over a few days, and how this may affect how much milk they drink, their feeding patterns, and their sleep.
- Trial name
- BOTTLE (NCT07665983)
- Testing
- Feeding
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity
Optimising Protection for Pregnant Women and Infants With Maternal Vaccination
This study has been designed to investigate if: 1. BMI affects the immunogenicity of influenza and pertussis vaccines given during pregnancy. 2.
- Trial name
- OPTIWIN (NCT03457194)
- Testing
- Quadrivalent Influenza Vaccine, DTP Vaccine (Multiple Actives)
- Where
- Australia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Women's and Children's Hospital, Australia
Obesity, Wolman Disease
Breakfast for Young Women
Investigators will in a crossover study test the health effects of eating a dairy-based protein-rich breakfast, isocaloric carbohydrate-rich breakfast or no breakfast in young overweight women.
- Conditions
- Obesity, Wolman Disease, Nutrition
- Trial name
- GoDag (NCT04652713)
- Testing
- Protein-rich breakfast, Carbohydrate-rich breakfast, No breakfast
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Maternal Behavior, Body Weight
Maternal and Infant Growth Study
Rapid growth early in infancy is a risk factor for obesity and cardiovascular disease later in the lifespan. Evidence is limited, but both pre- and postnatal factors are associated with early rapid growth, and include high…
- Conditions
- Maternal Behavior, Body Weight, Infant Behavior
- Trial name
- RIF (NCT02893319)
- Testing
- Feeding and growth differences, 5oz vs 8oz bottle
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Leann Birch
Obesity, Growth
Essential Fatty Acids During Complementary Feeding
The objective of this intervention study is to examine the effect of n-3 LCPUFA on growth and body composition, intestinal health and microbiotic composition, immune function and risk markers for later diseases in 9-18 months old…
- Conditions
- Obesity, Growth, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- EFiON (NCT00631046)
- Testing
- Fish Oil, Sunflower Oil
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sleep, Parenting
The Baby Care Study
The objective of this study is to provide pilot data on the feasibility and effectiveness of a web-based social networking intervention designed to promote sleep early in infancy and to explore the potential for this approach to…
- Conditions
- Sleep, Parenting, Eating Behavior, Obesity
- Trial name
- NCT05322174
- Testing
- Baby Sleep, Baby Care
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Pediatric Obesity, Weight Gain Trajectory
Assessing Better Bottles for Babies
This study will use a 2 x 2 factorial design to test impact of two intervention strategies (bottle size and bottle opacity) on infant weight gain.
- Conditions
- Pediatric Obesity, Weight Gain Trajectory, Infant Obesity
- Trial name
- AB3 (NCT06357299)
- Testing
- Small Bottle Size, Standard Bottle Size, Clear Bottle
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Obesity & Overweight
Healthy Eating for My Infant: A Community- Informed Infant Obesity Prevention Program Addressing the Impact of Maternal Mental Health on Eating and Feeding
Infants from low-income families are at increased risk for obesity, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT07284108
- Testing
- Healthy Eating for My Infant (HEMI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati