Clinical trials: Infant Outcomes
Neurodevelopmental Disorders, Motor Skills Disorders
Motor Development and Early Predictors of Psychomotor Outcomes in Preterm and Term Infants Assessed by MOS-R and Caregiver Questionnaire at 18 and 36 Months
This study examines how early motor behavior in infants relates to their later psychomotor development. Researchers will observe both preterm and full-term infants during the first months of life, using video-based assessments to…
- Conditions
- Neurodevelopmental Disorders, Motor Skills Disorders, Infant, Premature Development, Infant, Term Development
- Trial name
- NCT07296003
- Testing
- Vojta method
- Where
- 3 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Maternal Behavior, Alcohol Drinking
Adapting and Testing a Behavioural Intervention to Prevent FASD and Adverse Infant Outcomes
South Africa (SA) has a long history of social and health disparities, resulting in the world's highest rate of fetal alcohol spectrum disorder (FASD; 111.1 per 1,000), where lifelong negative cognitive and physical effects…
- Conditions
- Maternal Behavior, Alcohol Drinking, Fetal Conditions
- Trial name
- MaRISA+ (NCT05747599)
- Testing
- Intervention with contingent incentives and text-based support
- Where
- South Africa
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RTI International
Gut Health, Gastrointestinal Diseases
Improved Gut Health Outcomes Associated With Probiotics Fortified With Hydrolyzed Whey Protein in Infant Formula
The goal of this interventional clinical trial is to test the effectiveness of improving gut health in terms of frequency of bowel movements in newly born infants fed with Feihe investigational formula product containing…
- Trial name
- NCT06159088
- Testing
- Feihe Investigational Formula, Control Formula, Breastfeeding
- Where
- 3 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Low Birthweight, Stunting
Impact of Benazir Nashonuma Program (BNP) on Maternal and Child Nutritional Status
The purpose of this study is to evaluate the impact of Benazir Nashonuma Program (BNP) which includes specialized nutritious food (SNF) augmented with specific reproductive health interventions during pregnancy on proportion of…
- Conditions
- Low Birthweight, Stunting, Wasting, Malnutrition, Child
- Trial name
- NCT05836961
- Testing
- Benazir Nashonuma Program (BNP)
- Where
- Pakistan
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Infant Development
Mobile Health Intervention for Infants in Guatemala (18-m Intervention)
Promoting optimal development for children at risk in low- and middle-income countries (LMICs) is an important global health priority.
- Trial name
- NCT06195358
- Testing
- Mobile Health (Smartphone) Application, Printed Caregiving Materials
- Where
- Guatemala
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Stillbirth and Neonatal Mortality, Perinatal Mortality
Perinatal Mortality Outcomes Through Household Infection Pathways
The goal of this trial is to learn if replacing household soil floors with concrete floors can prevent deaths of infants around the time of birth, including stillbirths and deaths in the first month of life in rural Bangladesh.
- Conditions
- Stillbirth and Neonatal Mortality, Perinatal Mortality, Infant Mortality, Child Mortality
- Trial name
- POTH (NCT07620613)
- Testing
- Concrete household floor
- Where
- Bangladesh
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Stanford University
Preterm Infants, Pain
Effects of the Interventions Using Multiple Sensory Integrations on Preterm Infants' Stress-Related Outcomes
Frequent pain and distress may affect infants' brain and neural development, and highlight the need for relieve pain interventions.
- Trial name
- NCT03252327
- Testing
- Multiple Sensory Integrations
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Anemia, Iron-Deficiency
Effect of Umbilical Cord Milking on Iron Related Health Outcomes for Cesarean-Delivered Infants
This study aims to determine whether umbilical cord milking can improve iron related health outcomes for cesarean-delivered infants.
- Trial name
- NCT02892461
- Testing
- Umbilical cord milking
- Where
- 2 sites in China
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Peking University
Kangaroo Care
The Effect of Mother and Father Kangaroo Care on Newborn and Parent Outcomes in Premature Infants
First aim is to determine the effect of mother and father kangaroo care on the premature baby's Comfort Behavior level and physiological parameters (respiratory rate, heart rate, oxygen saturation and body temperature).
- Trial name
- NCT06195410
- Testing
- kangaroo care application
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Vulvovaginitis, Candidal, Vulvovaginal Candidiasis
Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes
This is an ongoing evaluation of subjects exposed to ibrexafungerp while pregnant. The study population will include pregnant women of any age.
- Conditions
- Vulvovaginitis, Candidal, Vulvovaginal Candidiasis, Candida Infection, Vaginal Candidiasis
- Trial name
- NCT05908682
- Testing
- Non-interventional study
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Iron Deficiency, Neonatal Hyperbilirubinemia
Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants
Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth.
- Trial name
- NCT01245296
- Testing
- Timing of clamping the umbilical cord
- Where
- Sweden
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Microbiota, Antibiotic Disruption
Antibiotic-induced Disruption of the Microbiota
The use of antibiotics causes profound changes in the microbiota. However, the magnitude of the effect of intrapartum and early-life antibiotics on the breast milk and the infant oral and intestinal microbiota, and whether…
- Trial name
- ABERRANT (NCT04091282)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy
The MOM-CARE Trial : Evaluating Antenatal and Postnatal MMSPlus for Improved Infant Birth and Growth Outcomes
This clinical trial aims to learn if MMS Plus improves infant health compared to standard MMS during pregnancy and the postnatal period in women living in peri-urban areas of Karachi, Pakistan.
- Conditions
- Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy, Nutrition During Pregnancy, Adaptive Trial
- Trial name
- MOM-CARE (NCT07029282)
- Testing
- MMS, MMS Plus, IFA
- Where
- Pakistan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Group B Streptococcus Carrier in Childbirth, Group B Streptococcal Infection, Late-Onset
Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital
Maternal immunisation is an evolving field that deserves special attention given its potential to have a significant positive impact on the health of women and children globally, and the potential safety and risk considerations…
- Conditions
- Group B Streptococcus Carrier in Childbirth, Group B Streptococcal Infection, Late-Onset, Group B Streptococcal Infection, Early-Onset, Group B Streptococcus Neonatal Sepsis
- Trial name
- PREPARE (NCT04653948)
- Where
- Uganda
- Volunteers
- 3,423 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
User Experience of Mobile Application
User Experience of a Mobile Application
To evaluate the user experience of the use of the different modules / trackers in the mobile application in recording primary caregiver reported outcomes of infants
- Trial name
- SMart (NCT04231188)
- Where
- Singapore
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Short Bowel Syndrome, Intestinal Failure
Infant & Toddler Short Gut Feeding Outcomes Study
The purpose of this study is to better understand why children with short gut develop feeding problems.
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Home Parenteral Nutrition
- Trial name
- NCT01946503
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Cognitive Change
Improved Cognitive Outcomes Associated With Feihe HMO With DHA/ARA in Infant Formula
The goal of this interventional clinical trial is to test the effectiveness of improving cognitive development in newly born infants fed with Feihe investigational formula product containing HMO, and DHA/ARA.
- Trial name
- NCT06146387
- Testing
- Investigational Formula, Control Formula, Breastfeeding
- Where
- 3 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Atopic Dermatitis (AD), Asthma
Post-authorization Safety Study in North America to Monitor Pregnancy and Infant Outcomes Following Administration of Dupilumab During Planned or Unexpected Pregnancy
The objective is to evaluate the potential effect of exposure to dupilumab in pregnancy compared to the primary comparison group of disease-matched pregnant women who are not exposed to dupilumab, and the secondary comparison…
- Trial name
- NCT04173442
- Testing
- dupilumab
- Where
- United States
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Premature Birth, Infant Development
Neonatal Experience of Social Touch
The purpose of this randomised control trial is to determine the efficacy of CT-optimal touch (gentle stroking at 3cm/s) for newborn's who require a heel prick.
- Conditions
- Premature Birth, Infant Development, Pain
- Trial name
- NEST (NCT05039918)
- Testing
- Affective touch
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Food Insecurity, HIV
PostNAPS: FI, Nutrition, and Psychosocial Health Among Women of Mixed HIV Status and Their Infants in Gulu, Uganda
PostNAPs was a continuation of the PreNAPs study. 246 women were enrolled in the postnatal period with the primary scientific objective of determining whether food insecurity was an independent risk factor for poor maternal…
- Conditions
- Food Insecurity, HIV, Maternal and Child Health, Nutrition
- Trial name
- PostNAPS (NCT02925429)
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Northwestern University