Clinical trials: Infant and Young Children
Respiratory Syncytial Virus Infection
A Phase III Study of Deuremidevir Hydrobromide for the Treatment of RSV Infection in Infants and Young Children
This is a randomized, double-blind, placebo-controlled, parallel-group trial conducted in infants and young children aged 1 to 36 months with RSV infection.
- Trial name
- NCT07402512
- Testing
- SIM0916
- Where
- 4 sites in China
- Volunteers
- 498 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
EBV Viremia, CMV Viremia
25BT056: Basket Study of Viral Cytotoxic T Lymphocytes
This study is evaluating the safety and effectiveness of virus-specific cytotoxic T lymphocytes (vCTLs) for treating difficult-to-control viral infections caused by cytomegalovirus (CMV), adenovirus (ADV), Epstein-Barr virus…
- Conditions
- EBV Viremia, CMV Viremia, BK Viremia, Adenovirus
- Trial name
- NCT07873970
- Testing
- Virus-Specific Cytotoxic T Lymphocytes (vCTLs)
- Volunteers
- 35 people
- Sponsor
- Children's Hospital of Philadelphia
Parent-Child Relations
Evaluating an Online Parenting Intervention for Caregivers of Infants and Young Children
The goal of this clinical trial is to evaluate the effectiveness of the online modality of the Make the Connection (MTC) program in caregivers of infants and young children.
- Trial name
- NCT05770414
- Testing
- Make the Connection® Online Program
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Ottawa
Cow's Milk Protein Allergy
Hypoallergenicity of a Hydrolyzed Rice Protein-based Formula in Infants and Young Children With Cow's Milk Protein Allergy
The purpose of the study is to determine whether a new hydrolyzed rice protein-based formula is hypoallergenic in infants and young children with documented Immunoglobulin E (IgE)-mediated Cow Milk Protein Allergy (CMPA).
- Trial name
- RIGHT-HY (NCT06633289)
- Testing
- Experimental formula, Control formula
- Where
- 11 sites in Germany, Italy and 1 more
- Volunteers
- 43 people
- Sponsor
- Société des Produits Nestlé (SPN)
Central Nervous System Embryonal Neoplasm
Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children
RATIONALE: Genetic studies may help in understanding the genetic processes involved in the development of some types of cancer. PURPOSE: Genetic study to learn more about genes involved in the development of central nervous…
- Trial name
- NCT00010114
- Where
- 9 sites in United States
- Volunteers
- 83 people
- Sponsor
- Pediatric Brain Tumor Consortium
Coarctation of the Aorta, Pulmonary Artery Stenosis
Growth Trial: Study of the Renata Minima Stent
The objective of the clinical investigation is to access clinical safety and effectiveness of the Minima Stent in neonates, infants, and young children requiring intervention for common congenital vascular stenosis (i.e.…
- Trial name
- NCT05086016
- Testing
- Catheterized Stenting
- Where
- 7 sites in United States
- Volunteers
- 42 people
- Sponsor
- Renata Medical
Blood Oxygen Desaturations, Sleep-Disordered Breathing
Assessment of the Accuracy of the Non-invasive Wireless Armband Gabi Baby Band for Continuous Vital Parameters Monitoring in Infants and Young Children
During a polysomnography test (PSG) previously prescribed by a physician, the patient also wears the Gaby Baby Band (GBB) during an entire night of sleep.
- Trial name
- WAGSC1 (NCT04886583)
- Testing
- Gabi Baby Band
- Where
- 3 sites in Belgium
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Medulloblastoma
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
This is a multi-center, multinational phase 2 trial that aims to explore the use of molecular and clinical risk-directed therapy in treatment of children 0-4.99 years of age with newly diagnosed medulloblastoma.
- Trial name
- NCT05535166
- Testing
- Surgical resection, Ommaya/VPS, Methotrexate
- Where
- 10 sites in United States
- Volunteers
- 130 people
- Sponsor
- St. Jude Children's Research Hospital
Infant
Exploration of Infant and Young Child Feeding Practices and Their Determinants
The goal of this observational study is to assess infant and young child-feeding practices among women living in urban areas and slums in Pune and rural areas around Pune, India, and to investigate the reasons for the adopted…
- Trial name
- NCT06307951
- Testing
- No intervention
- Where
- India
- Volunteers
- 271 people
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Health Education, Community, Diet, Food, and Nutrition
Change in Child-feeding Knowledge, Attitudes, and Practices With Nutrition Education Mass Media in Ghana
Optimal infant and young child feeding practices are largely inadequate in rural and poor households in Ghana. Child welfare clinics (CWCs) focus on immunization, supplementation, and growth monitoring and promotion (GMP)…
- Conditions
- Health Education, Community, Diet, Food, and Nutrition, Malnutrition, Infant Nutritional Sciences
- Trial name
- NCT02800564
- Testing
- Active mass media approach, Passive mass media approach
- Where
- 4 sites in Canada, Ghana
- Volunteers
- 689 people, healthy volunteers welcome
- Sponsor
- McGill University
Iron Deficiency Anemia
Comparison of NovaFerrum® vs Ferrous Sulfate Treatment in Young Children With Nutritional Iron Deficiency Anemia
This study is a randomized, controlled, double-blinded single center trial to compare the efficacy of NovaFerrum® to ferrous sulfate for the treatment of nutritional iron deficiency anemia (IDA) in infants and young children.
- Trial name
- BESTIRON (NCT01904864)
- Testing
- elemental iron (NovaFerrum®), elemental iron (Ferrous Sulfate)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Cryptosporidium; Diarrhea, Cryptosporidiosis
Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
The aim of the study is to examine the efficacy of ceramic water filters to reduce the burden of waterborne diarrheal illness among infants in selected villages in Kenya.
- Conditions
- Cryptosporidium; Diarrhea, Cryptosporidiosis, Communicable Diseases, Diarrheal Disease
- Trial name
- NCT01695304
- Testing
- Ceramic water filter
- Where
- Kenya
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Malnutrition, Anemia
Building Capacity for Sustainable Livelihoods and Health
Despite recent economic growth in Ghana, the prevalence of childhood malnutrition remains high. Wasting prevalence affected 29% among 6- to 8-months-old infants in 2008.
- Trial name
- NCT01985243
- Testing
- Nutrition and agriculture, Iron-rich food & business literacy
- Where
- 3 sites in Canada, Ghana
- Volunteers
- 3,390 people, healthy volunteers welcome
- Sponsor
- McGill University
Anorexia Nervosa, Eating Disorders
Perceptions of Their Own Body and of the Body of Their Child Among Young Mothers With Anorexia Nervosa
The BodyBabe studies aims to evaluate the perceptions that young mothers with anorexia nervosa (active or in remission) have of their own body and of the body of their child.
- Trial name
- BodyBabe2 (NCT05246696)
- Testing
- BodyBabe questionnaire
- Sponsor
- University Hospital, Clermont-Ferrand
Nutritional Status
Assessing the Effectiveness of Strengthening the Growth Monitoring and Promotional Activities in Rural Bangladesh
Background: To tackle the high burden of undernutrition, the government of Bangladesh has identified growth monitoring and promotion (GMP) as a priority activity in the National Nutrition Services operational plan.
- Trial name
- GMP (NCT03824756)
- Testing
- NGO supported GMP program, Non-supported GMP program
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
HPV Vaccine
Strengthening HPV Immunization Through EPI Leveraged Delivery
This is a randomized observer-blind placebo-controlled proof-of-concept study with the aim to assess the safety and tolerability, and the immunogenicity of a bivalent HPV vaccine administered in healthy infants and toddlers (9…
- Trial name
- SHIELD (NCT07377656)
- Testing
- HPV vaccine, Measles and rubella Vaccine
- Where
- Ghana
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Pneumococcal Infectious Disease
PCV24 Clinical Trial in Infants and Young Children Aged 2 Months (Minimum 6 Weeks) to 71 Months
The Phase II clinical trial of the 24-valent pneumococcal polysaccharide conjugate vaccine (RZ700) will be carried out in infants and young children aged 2 months (minimum 6 weeks) to 71 months.
- Trial name
- NCT07333352
- Testing
- 24-Valent Pneumococcal Polysaccharide Conjugate Vaccine (RZ700), 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine (Prevnar 13)
- Where
- 7 sites in China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Reinovax Biologics Co., LTD
Healthy
Study of Body Composition Methodology in Young Children (InfantPod)
The InfantPod study is a cross-sectional study designed to determine how practical and precise a body composition method is for measuring body fat and lean tissue in infants and children ages 5 months to 3 years.
- Trial name
- NCT00730587
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Energy Expenditure, Body Composition
Energy Expenditure and Body Composition of Infants and Young Children (6-24 Months Old) in Asia
This project is a collaboration between International Atomic Energy Agency (IAEA), FAO Regional Office for Asia and The Pacific, and Mahidol University, Thailand to carry out the study on doubly-labeled water for assessment of…
- Conditions
- Energy Expenditure, Body Composition, Infants and Young Children, Infant and Young Child Feeding
- Trial name
- NCT06287697
- Testing
- No intervention
- Where
- Thailand
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Anemia, Iron Deficiency Anemia
The Use of Ultra Rice Compared to Iron Drops Consumed by Anemic Children
Background: How best to improve iron status among infants in low-income settings is of continued concern in many countries, including Brazil Objective: Design: In a double blind, 5-mo, home-based trial in Brazil, mildly anemic 6…
- Trial name
- NCT00839761
- Testing
- iron fortified rice, iron drops
- Where
- Brazil
- Volunteers
- 175 people
- Sponsor
- Federal University of Minas Gerais