Clinical trials: Infected Surgical Wound
Surgical Site Infection, Brain Tumor
Infection Prevention Bundle in Brain Tumor Surgery
This study aimed to evaluate the effectiveness of an infection prevention bundle on surgical site infections in patients undergone brain tumor surgery.
- Trial name
- NCT04285697
- Testing
- infection prevention bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Surgical Wound Infection
The Use of a Silver Containing Dressing (Acticoat) on Wound Complication Rates Post Elective Cesarean Section
The purpose of this study is to determine the effect of a silver containing dressing (Acticoat Post-Op) compared to a standard dressing (OpSite PostOp) on post elective cesarean section wound complications in obese women (BMI…
- Trial name
- NCT02288884
- Testing
- Acticoat PostOp, OpSite PostOp
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Post-Operative Wound Infection
A Tetracycline Drain Reduces Alveolar Osteitis in Third Molar Surgery
The aim of this study was to investigate the effect of an oxytetracycline impregnated gauze drain on the incidence of alveolar osteitis (AO) and postoperative pain during the first week after mandibular third molar surgery.
- Trial name
- Wisdomsteeth (NCT03494972)
- Testing
- Tetracyclin ointment
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Prosthesis and Implants, Surgical Site Infection
Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-III)
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if PDT has an effect on bacterial skin colonization in order to improve skin antisepsis…
- Conditions
- Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection, Postoperative Wound Infection Deep Incisional Surgical Site
- Trial name
- NCT05676801
- Testing
- Photodynamic Therapy
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Surgical Site Infection, Surgical Wound Infection
Floraseal Versus Iodine Impregnated Adhesive Drapes
Infection after total joint arthroplasty can have devastating consequences. Adhesive drapes have been traditionally used at our institution to help reduce the risk of wound contamination and infection by superficial skin flora.
- Trial name
- NCT03466489
- Testing
- Floraseal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Surgical Site Infection, Difference in Surgical Site Infection According to Gender and Age Groups
COMPARISON OF PURSE-STRING CLOSURE VERSUS CONVENTIONAL PRIMARY CLOSURE FOLLOWING STOMA REVERSAL TO REDUCE SURGICAL SITE INFECTION RATE"
The study will be carried out in Surgical Unit-III, Lahore General Hospital, Lahore for one year . . Patients undergoing surgery for Ileostomy will be randomly divided into two groups, Group-A (Purse-string closure) and Group-B…
- Trial name
- NCT04757623
- Testing
- Purse string closure of Ileostomy
- Where
- 2 sites in Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital, Pakistan
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Trauma, Orthopedic Surgery Complications
The Infected Bone Nonunion and Soft Tissue Defect of Long Bone Treated Simultaneously With Ilizarov Technique
In this retrospective study, the investigators evaluated the clinical and functional results of infected nonunion of the long bone with soft-tissue defects treated simultaneously with Ilizarov technique combining open dressing…
- Trial name
- NCT00846261
- Testing
- Use it to treatment bone nonunion (Ilzarov)
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Periimplantitis, Dental Plaque
Antimicrobial Activity of Two Mouthwashes
This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.
- Conditions
- Periimplantitis, Dental Plaque, Periodontal Diseases, Caries
- Trial name
- NCT02375178
- Testing
- chlorhexidine, Polyhexamethylene biguanide, Sterile saline solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Total Joint Arthroplasty, Risk Reduction
Arthroplasty and Modifiable Risk Factors
Hip and knee total joint arthroplasty are one of the most frequently performed surgery worldwide. However, prosthetic joint infection remains a devastating complication of them, associated with severe morbidity, increased…
- Conditions
- Total Joint Arthroplasty, Risk Reduction, Surgical Site Infection, Prosthetic-joint Infection
- Trial name
- NCT05399186
- Testing
- Early preoperative assessment and optimization
- Where
- Iceland
- Volunteers
- 1,484 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Skin Lesion
The Effect of Prophylactic Antibiotics on Surgical Site Infection Lower Limb Skin Excisions
The incidence of surgical site infection (SSI) infection in clean dermatologic surgery is very low, between 1-3%. Studies have demonstrated a much higher infection rate in skin excision surgeries in the lower limbs, up to 10% in…
- Trial name
- NCT03357419
- Testing
- Cephalexin
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Surgical Site Infections, ARSC Motivation Model
The Effect of an ARCS Model-Based Escape Room Simulation on Nursing Students' Knowledge, Motivation, and Self-Efficacy Regarding Surgical Site Infections
The study is designed as a randomized controlled trial with an experimental and control group, using a pre-test, post-test, and follow-up test design.
- Conditions
- Surgical Site Infections, ARSC Motivation Model, Escape Room Simulation
- Trial name
- NCT07551973
- Testing
- Escape Room Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Surgical Wound Infection
Circular pOlyethylene Drape in preVention of Surgical Site infEction: A Randomized Controlled Trial
This study is to evaluate the effectiveness of the plastic ring wound retractor to reduce the rate of surgical site infection in patients who undergo open abdomen surgery for gastrointestinal tract.
- Trial name
- COVER (NCT03170843)
- Testing
- use of plastic ring wound retractor
- Where
- 13 sites in South Korea
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Saint Vincent's Hospital, Korea
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Infection
Measures for the Prevention of Surgical Site Infection
Among the causes associated with infection of hospitalized patients, surgical site infection is a complication that is potentially associated with any type of surgical procedure, it also represents an expressive burden in terms…
- Trial name
- Orthopedics (NCT03551561)
- Testing
- CSAAC, CSAC
- Where
- Brazil
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Cesarean Section
The Effect of Forced Air Warming During Cesarean Section on Postoperative Infectious Morbidity
The purpose of this study will be to assess whether forced air warming decreases the rate of surgical site infections following cesarean section.
- Trial name
- NCT00696462
- Testing
- forced-air warming
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University
Surgical Site Infections
The Skin Prep Study
The investigators propose a randomized controlled clinical trial to determine the comparative effectiveness of chlorhexidine-alcohol and iodine-alcohol preoperative skin preparation for preventing surgical site infections at…
- Trial name
- NCT01472549
- Testing
- Iodine-alcohol, Chlorhexidine-alcohol
- Where
- United States
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Surgical Site Infections
PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
To study the effect of applying a PHMB-based antiseptic solution to tie-over dressings in full-thickness surgical wounds in dermatologic surgery in order to minimise the development of surgical site infections.
- Trial name
- NCT02253069
- Testing
- Applying Prontosan antiseptic solution to tie-over dressings
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Infection; Cesarean Section, Surgical Wound Infection
Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity
Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are…
- Conditions
- Infection; Cesarean Section, Surgical Wound Infection, Endometritis
- Trial name
- Peri-Op (NCT00603603)
- Testing
- 80% inhaled oxygen via non-rebreather mask, 30% inhaled oxygen via nasal cannula
- Where
- United States
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine