Clinical trials: Infected Wound
Diverticulitis, Surgical Site Infection
Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial
The goal of this observational study is to learn if a new surgical technique, called the NICE procedure, is as safe as standard methods for treating benign left-sided colon and rectal diseases in adults.
- Conditions
- Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery
- Trial name
- NCT06957236
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Methodist Hospital Research Institute
Surgical Site Infection
Pilot Clinical Evaluation to Characterize in Vivo Effects of Topically Applied ZuraPrep & ZuraPrep Vehicle
ZuraPrep is being evaluated for efficacy as a preoperative skin preparation solution to demonstrate its immediate and persistent antimicrobial properties.
- Trial name
- NCT02578771
- Testing
- ZuraPrep with 70% IPA, ZuraPrep without 70% IPA, ChloraPrep CHG/IPA Teal Tint
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Wound Infection
Abdominal Wall Closure With Triclosan-coated Suture (TCS09-10)
After open colo-rectal surgery the surgical site infection (SSI) is very high among abdominal surgeries. The goal of the investigators randomized, prospective, multicentric, internet-based study is to compare rate of SSI after…
- Trial name
- NCT01123616
- Testing
- abdominal wall closure
- Where
- Hungary
- Volunteers
- 1 people
- Sponsor
- University of Pecs
Elective Colon Surgery
Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery
The REaCT NSQIP will compare oral antibiotics vs. no antibiotics, which are two standards of care treatments for preoperative preparation of the bowel prior to colorectal surgery
- Trial name
- REaCT-NSQIP (NCT03663504)
- Testing
- No Preparation, Neomycin and Flagyl
- Where
- 6 sites in Canada
- Volunteers
- 630 people
- Sponsor
- Ottawa Hospital Research Institute
Staphylococcus Aureus Infection, Surgical Site Infection
Serum Based Diagnosis of and Monitoring of Infection Recovery in Orthopedic Spine Implant Infections
The goal of this study is to test a new way to diagnose and track treatment of spine infections caused by the bacteria Staphylococcus aureus.
- Conditions
- Staphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, Spine
- Trial name
- NCT04897971
- Testing
- Medium enriched for newly synthesized antibodies in spine infection
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Ear Infection Bacterial, Surgical Site Infection
Use of Preoperative and Postoperative Antimicrobial Treatment
In this study, patients undergoing ear surgery (cochlear implantation, stapedotomy, tympanoplasty) will be randomized to one of two antibiotic treatment groups.
- Conditions
- Ear Infection Bacterial, Surgical Site Infection, Antibiotic Side Effect
- Trial name
- NCT04707092
- Testing
- Antibiotic
- Where
- Canada
- Volunteers
- 304 people
- Sponsor
- Sunnybrook Health Sciences Centre
Staphylococcus Aureus, Wound Infection, Surgical
Staphylococcus Aureus Surgical Site Infection Multinational Epidemiology in Europe
This is a retrospective multinational, multicenter cohort study with a nested case-control. The study includes all surgical procedures performed at a participating site to prevent bias. Data will be assessed in two populations.
- Conditions
- Staphylococcus Aureus, Wound Infection, Surgical, Epidemiology
- Trial name
- SALT (NCT03353532)
- Where
- 14 sites in France, Germany and 3 more
- Volunteers
- 178,902 people
- Sponsor
- University of Cologne
Evaluate to Effects of Two Antiseptic Products and Showering
CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE
The study was planned to evaluate the effects of two most commonly used antiseptic products and showering on the healing process, such as wound healing and postoperative maternal comfort in cesarean section.
- Trial name
- NCT05953714
- Testing
- incision side cleaning with antiseptic products
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Sakarya University
Late Effects of Surgery, Staphylococcus Aureus
Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery
This investigation is a prospective, open-label pharmacokinetic study of daptomycin prophylaxis in patients undergoing coronary artery bypass graft surgery without valvular replacement.
- Conditions
- Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
- Trial name
- NCT00701636
- Testing
- daptomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Parotidectomy
Timing of Postoperative Drain Removal Following Parotidectomy - a Prospective Randomized Controlled Study
There is no standard of care of management following parotidectomies. Most practitioners however place a drain (usually a flat Davol closed suction drain/ Hemovac in the investigators institutions) in the wound bed at the end of…
- Trial name
- NCT01399021
- Testing
- Early Drain Removal, Late Drain Removal
- Where
- 4 sites in Canada
- Volunteers
- 400 people
- Sponsor
- University of British Columbia
Presence of Ileostomy
Need for Subcutaneous Wound Drains in Ileostomy Reversal
The purpose of this study is to find out whether the insertion of subcutaneous wound drains has an influence on postoperative hospital stay in ileostomy reversal.
- Trial name
- DRASTAR (NCT01050686)
- Testing
- insertion of subcutaneous wound drain, no insertion of subcutaneous wound drain
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Charite University, Berlin, Germany
Surgical Site Infection
Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection
Surgical site infections (SSI) are the most common healthcare-associated infections and sources of morbidity and over-mortality.
- Trial name
- NCT06108791
- Testing
- FIO2=0.8, FIO2=0.33
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Assiut University
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Wound Infection
To Assess Use of Vancomycin Powder in Craniotomy on Wound Infection Rates
Surgical site infection (SSI) after craniotomy is a major cause of morbidity and mortality besides its major health care cost. In each hospital, all measures are taken to decrease SSI.
- Trial name
- NCT04917627
- Testing
- Vancomycin
- Where
- Qatar
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hamad General Hospital
Surgical Site Infection
AO Multicenter Intervention Trial for Prevention of Surgical Site Infection
This study is designed to collect data from 8,476 fracture patients during a pre-and post-intervention phases of two years length each. The intervention consists on the implementation of the AOT SSI Prevention Bundle. D
- Trial name
- AOPOSSI (NCT03380273)
- Testing
- Implementation of the AO Trauma SSI Prevention Bundle
- Where
- 14 sites in United States, Argentina and 4 more
- Volunteers
- 222 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Postoperative Wound Infection Superficial Incisional, Postoperative Wound Infection Deep Incisional Surgical Site
Is the NPWTi Better Than the Conventional NPWT
The goal of this clinical trial is to compare the effectiveness of NPWTi and NPWT in superficial and deep surgical site infections using an improvised system with continuous lavage with saline and chlorhexidine.
- Trial name
- NCT06014788
- Testing
- NPWTi, Conventional NPWT
- Where
- Bulgaria
- Volunteers
- 100 people
- Sponsor
- Military Medical Academy, Bulgaria
Bacterial Infections, Antibiotic Resistant Infection
Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan
The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.
- Conditions
- Bacterial Infections, Antibiotic Resistant Infection, Surgical Site Infection
- Trial name
- NCT05106803
- Testing
- ciprofloxacin
- Where
- Jordan
- Volunteers
- 24 people
- Sponsor
- Yarmouk University
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Wound Infection
Randomized Trial to Assess PO Versus IV Antibiotics
The goal of this study is to evaluate the effect of treatment of post-op wound infection in long bones after fracture fixation or joint fusion and either: (Group 1) operative debridement and PO antibiotic treatment for 6 weeks…
- Trial name
- POvIV (NCT01714596)
- Testing
- PO versus IV antibiotics Route of administration evaluation
- Where
- 24 sites in United States
- Volunteers
- 233 people
- Sponsor
- Major Extremity Trauma Research Consortium
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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