Clinical trials: Infection Prophylaxis
Noncommunicable Diseases, Health Knowledge, Attitudes, Practice
School-based e-Health Non-Communicable Disease (NCD) Prevention Program
The goal of this sequential mixed method study is to assess the feasibility and effectiveness of a school-based eHealth-NCD prevention program intervention to improve adolescents' knowledge, attitude, and practices regarding NCDs…
- Conditions
- Noncommunicable Diseases, Health Knowledge, Attitudes, Practice, Non-communicable Disease Risk Factors
- Trial name
- NCT06674798
- Testing
- School-based eHealth NCD Prevention Program
- Where
- 7 sites in Pakistan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Kidney Cancer, Leukemia
Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy
RATIONALE: Voriconazole may be effective in preventing systemic fungal infections following chemotherapy. PURPOSE: Phase II trial to study the effectiveness of voriconazole in preventing systemic fungal infections in children who…
- Conditions
- Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00066599
- Testing
- voriconazole
- Where
- 7 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Gastroenteric Tract, Respiratory Tract
Efficacy of a 2'-Fucosylactose-based Food Supplement on the Prevention of Respiratory and Gastrointestinal Infections.
Respiratory and gastrointestinal infections are frequent problems in children under 4 years of age, especially after the start of schooling.
- Conditions
- Gastroenteric Tract, Respiratory Tract, Infections, Gastroenteric Infections
- Trial name
- IMMUNOSICK24 (NCT07050693)
- Testing
- Vitamin + Zinc + micronutrient mixture
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Sexually Transmitted Diseases, HIV Infections
UTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM
This project seeks to develop and test the acceptability, appropriateness and feasibility of uTECH, a novel social media "big data" machine learning intervention for HIV-negative substance-using sexual and gender minority people…
- Conditions
- Sexually Transmitted Diseases, HIV Infections, Implementation Science, Substance Use
- Trial name
- uTECH (NCT04710901)
- Testing
- uTECH + YMHP, YMHP, uTECH
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV, HIV Pre-exposure Prophylaxis
Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)
This double-blind, placebo-controlled study was designed to assess the safety, tolerability, and pharmacokinetics of oral MK-8527 taken once monthly (QM) in participants at low risk for human immunodeficiency virus Type 1 (HIV-1)…
- Trial name
- NCT06045507
- Testing
- MK-8527
- Where
- 18 sites in United States, Israel and 1 more
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Prevention, STD Prevention
Adopting and Demonstrating the Adaptation of Prevention Techniques: Community PROMISE PLUS
This project will pilot test a step-by-step guide developed by CDC for organizations to engage in evidence-based adaptation of interventions previously shown to be effective in research settings for use in real world…
- Trial name
- NCT00267436
- Testing
- Community PROMISE
- Where
- 2 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Influenza, Human
Prophylactic Treatment With Oseltamivir
The purpose of this study is to compare the efficacy of 5-day versus 10-day oseltamivir prophylactic treatment in patients who had been exposed to influenza.
- Trial name
- NCT03899571
- Testing
- Oseltamivir Oral Capsule for 5 days post-exposure, Oseltamivir Oral Capsule for 10 days post-exposure
- Where
- Slovenia
- Volunteers
- 222 people
- Sponsor
- University Medical Centre Ljubljana
HIV Infections
A School-Based HIV/STD Prevention Program to Reduce Risky Sexual Behaviors Among Adolescents in Liberia
This study will evaluate the effectiveness of a school-based HIV/sexually transmitted disease prevention program in reducing sexual risk behaviors of youth attending school in Liberia.
- Trial name
- NCT00698321
- Testing
- HIV/STD prevention curriculum, General health promotion curriculum
- Where
- Liberia
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Chronic Lymphocytic Leukemia, Hypogammaglobulinemia
Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients With Chronic Lymphocytic Leukemia ("PRO-SID" Study)
Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients with Chronic Lymphocytic Leukemia
- Trial name
- NCT04502030
- Testing
- Panzyga
- Where
- 84 sites in United States, Czechia and 10 more
- Volunteers
- 247 people
- Sponsor
- Octapharma
Anorectal Surgeries
Transdermal Continuous Oxygen Therapy for Infection Prophylaxis in High- Risk Patients Undergoing Colon Surgery
EPIFLO® unit along with standard wound care vs only standard wound care for Surgical site infections (SSI).
- Trial name
- NCT02617706
- Testing
- Epiflo
- Where
- United States
- Sponsor
- Neogenix, LLC dba Ogenix
Kidney Stones
Struvite Stones Antibiotic Study
The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).
- Trial name
- NCT02375295
- Testing
- ciprofloxacin, cotrimoxazole-trimethoprim, macrodantin
- Where
- 12 sites in United States, Canada
- Volunteers
- 28 people
- Sponsor
- University of British Columbia
Acute Renal Failure, Infection
Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial
The primary objective of the study is to demonstrate the efficacy of 60% ethanol lock solution in preventing major catheter related infections in critically ill patients.
- Trial name
- ELVIS (NCT00875069)
- Testing
- Ethanol
- Where
- France
- Volunteers
- 1,460 people
- Sponsor
- University Hospital, Clermont-Ferrand
Infection
Antibiotic Prophylaxis in Total Knee Prosthesis
Knee prosthesis infection is a severe complication. The use of a tourniquet during surgery impairs the efficacy of the antibiotic prophylaxis.
- Trial name
- NCT00497341
- Testing
- cefuroxime
- Where
- Spain
- Volunteers
- 1,332 people
- Sponsor
- Hospital Clinic of Barcelona
Kidney Cancer, Leukemia
Traumeel® S in Preventing and Treating Mucositis in Young Patients Undergoing Stem Cell Transplantation
RATIONALE: Traumeel® S (a mouth rinse) may be effective in preventing or decreasing the severity of oral mucositis caused by chemotherapy in young patients who are undergoing stem cell transplantation.
- Conditions
- Kidney Cancer, Leukemia, Lymphoma, Neuroblastoma
- Trial name
- NCT00080873
- Testing
- Traumeel S
- Where
- 44 sites in United States, Australia and 2 more
- Volunteers
- 195 people
- Sponsor
- Children's Oncology Group
Malaria Infection, Malaria Vaccines
Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad
This is a two-arm, cluster-randomised, phase IV trial conducted in Chad to assess the protective efficacy and impact in real-life conditions of a new strategy for administering the R21/MM malaria vaccine, synchronized within a…
- Trial name
- COSAV-R21 (NCT07038837)
- Testing
- "Synchronised" arm (intervention)
- Where
- Chad
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Epicentre
Chronic Wound Care, Local Infection
Short-Term Safety and Performance of Two Wound Dressings Evaluation
Chronic wounds, including venous leg ulcers, diabetic foot ulcers, and pressure ulcers, are defined as wounds that fail to heal within 4-8 weeks despite appropriate care.
- Conditions
- Chronic Wound Care, Local Infection, Safety
- Trial name
- POLTX_Fiber (NCT07576322)
- Testing
- Politix Fiber arm
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Sebastian Probst
Surgical Wound Infection
The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal
The goal of this clinical trial is to learn if reducing bacterial load on the skin and nostrils with topical antibacterial soap and ointment, respectively, reduces rate of infection in surgical sites on lower leg wounds left open…
- Trial name
- NCT07142408
- Testing
- Chlorhexidine gluconate (4%), Mupirocin 2% Ointment
- Where
- United States
- Volunteers
- 848 people
- Sponsor
- Cooper Norcross Health
Postoperative Infection, Postoperative Complications
Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Infection and wound complications are the most common complications following orthopaedic foot and ankle procedures, and the infection rate following these procedures is higher than in procedures involving other areas of the…
- Trial name
- NCT03926208
- Testing
- Soak and Scrub, Clorhexadine scrub
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Rush University Medical Center
HIV-1 Infection, Risk Reduction
HIV Internet Sex Study: Internet-based STI/HIV Prevention for HIV+ Internet Users
The goal of this study was to empirically test a newly developed online HIV sexual risk reduction intervention (HINTS) among a representative sample of gay and bisexual men living with HIV who meet sex partners online.
- Trial name
- HINTS (NCT02887508)
- Testing
- HINTS Intervention, Healthy Living Control
- Volunteers
- 170 people
- Sponsor
- University of Connecticut
Maternal Death, Maternal Infections Affecting Fetus or Newborn
Azithromycin-Prevention in Labor Use Study (A-PLUS)
Maternal and neonatal infections are among the most frequent causes of maternal and neonatal deaths, and current antibiotic strategies have not been effective in preventing many of these deaths.
- Conditions
- Maternal Death, Maternal Infections Affecting Fetus or Newborn, Neonatal SEPSIS, Maternal Sepsis During Labor
- Trial name
- NCT03871491
- Testing
- Azithromycin
- Where
- 8 sites in Bangladesh, Democratic Republic of the Congo and 5 more
- Volunteers
- 58,747 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.