Clinical trials: Infection Prophylaxis
Sexually Transmitted Diseases, Chlamydia Trachomatis
A Randomized Online Health Experiment for a Safer Youth Sexual Behaviour
The objective of this project is to assess the impact of a Game-Based Appointment System on both, the clinical settings, and on the use of the educational web app www.sjekkdeg.no. An A/B testing methodology will be used.
- Trial name
- NCT02128620
- Testing
- Game-Based Appointment System
- Where
- Norway
- Volunteers
- 996 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Mpox (Monkeypox)
An Immunogenicity and Safety Trial of MVA-BN in Adults Living With HIV for the Prevention of Mpox Infection, in Kinshasa, DRC
This is an open-label, phase 2, immunogenicity and safety trial of the MVA-BN vaccine for the prevention of mpox in adults living with HIV with different level of CD4 counts in Kinshasa, DRC.
- Trial name
- Mbote-HIVAX (NCT06839989)
- Testing
- Mpox vaccination with MVA-BN
- Where
- Democratic Republic of the Congo
- Volunteers
- 600 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Letemovir for the Prevention of CMV Infection After Allo-HSCT
Observational Clinical Study of Letermovir for Preventing CMV Infection After Allo-HSCT
The goal of this observational study is to get a series of clinical data related to the prevention of CMV infection after allo-HSCT with letemovir.
- Trial name
- NCT06306989
- Testing
- Letermovir
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Cao Weijie
Measles, Rubella
Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases
This is a study to evaluate the immunogenicity and safety of GlaxoSmithKline (GSK) Biologicals combined measles-mumps-rubella varicella candidate vaccine given to healthy children in their second year of life.
- Conditions
- Measles, Rubella, Mumps, Varicella
- Trial name
- NCT00127010
- Testing
- Measles, Mumps, Rubella and Chickenpox (live vaccine)
- Where
- 48 sites in Belgium, Germany and 1 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cytomegalovirus Infection
Extension of Letermovir (LET) From Day 100 to Day 200 Post-transplant for the Prevention of Cytomegalovirus (CMV) Infection in Hematopoietic Stem Cell Transplant (HSCT) Participants (MK-8228-040)
The purpose of this study was to evaluate the safety and efficacy of letermovir (LET) versus placebo when cytomegalovirus (CMV) prophylaxis was extended from 100 days to 200 days post-transplant in CMV seropositive participants…
- Trial name
- NCT03930615
- Testing
- Letermovir
- Where
- 32 sites in United States, France and 4 more
- Volunteers
- 220 people
- Sponsor
- Merck Sharp & Dohme LLC
Malaria, Anaemia
Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy
Among the best practices recommended for malaria control during pregnancy is ensuring effective case management of malaria illness.
- Conditions
- Malaria, Anaemia, Pregnancy
- Trial name
- NCT00432367
- Testing
- Amodiaquine plus artesunate combination; sulphadoxine-pyrimethamine
- Where
- Ghana
- Volunteers
- 3,333 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Rabies Prevention
Early Rabies Vaccine Immunization in Primary School Children
700 male and female healthy school-children (age 5 to 8) in Thailand were randomized to receive 2 or 3 primary rabies vaccine doses (PCECV, Rabipur) given intradermally in a dose of 0.1mL into the skin in the deltoid region.
- Trial name
- I49P1 (NCT01107275)
- Testing
- rabies vaccine
- Where
- Thailand
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- Provincial Public Health Office, Phetchabun
Asthma, Asthma Exacerbations
Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers
In this 7-month randomized controlled trial, children aged 1 to less than 6 years, with recurrent asthma attacks triggered mostly by colds, will receive a high dose of vitamin D or a placebo every 3.5 months during their usual…
- Conditions
- Asthma, Asthma Exacerbations, Preschool Child, Vitamin D
- Trial name
- DIVA (NCT03365687)
- Testing
- Vitamin D
- Where
- 9 sites in Canada
- Volunteers
- 323 people
- Sponsor
- Professor Francine Ducharme
Tetanus
A Registry： Siltartoxatug Injection for Tetanus Prophylaxis Following Injury
The injury and wound conditions of the enrolled patients will be documented. A follow-up at 90 days post-administration will determine the clinical outcome of tetanus prophylaxis, specifically whether tetanus occurred.
- Trial name
- NCT07107932
- Testing
- Siltartoxatug Injection (Brand name: Sintetol®)
- Where
- 4 sites in China
- Volunteers
- 10,000 people
- Sponsor
- Zhuhai Trinomab Pharmaceutical Co., Ltd.
HIV/AIDS
Motivation Matters Study
The study aims to develop and evaluate the efficacy and causal mechanisms of an interactive SMS intervention to optimize individual health and secondary HIV prevention benefits of ART in HIV-positive FSWs.
- Trial name
- MM (NCT02627365)
- Testing
- Individualized, interactive short messaging intervention
- Where
- Kenya
- Volunteers
- 119 people
- Sponsor
- University of Washington
HIV Infections
Screen Smart: Using Digital Health to Improve HIV Screening and Prevention
The goal of this interrupted time series quasi-experimental design study is to implement universal opt- out HIV testing and linkage to HIV preventive care in 15-21 year old adolescents visiting the pediatric emergency department…
- Trial name
- Screen Smart (NCT06003192)
- Testing
- Universal Opt-out HIV Screening
- Where
- 4 sites in United States
- Volunteers
- 63,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
CIN 2/3, HPV Infection
Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)
This is a phase II double blind, placebo-controlled, randomized study of Artesunate vaginal inserts for the treatment of women who have cervical high grade intraepithelial neoplasia (CIN2/3).
- Conditions
- CIN 2/3, HPV Infection, Pre-Cancerous Dysplasia, Cervical Dysplasia
- Trial name
- ART-CIN_IIB (NCT04098744)
- Testing
- Artesunate vaginal insert
- Where
- 7 sites in United States
- Volunteers
- 78 people
- Sponsor
- Frantz Viral Therapeutics, LLC
Ebola Hemorrhagic Fever, Ebola Virus Disease
Experimental Vaccine for Prevention of Ebola Virus Infection
This study will determine if an experimental vaccine to prevent Ebola virus infection is safe and what side effects, if any, it causes.
- Conditions
- Ebola Hemorrhagic Fever, Ebola Virus Disease, Ebola Virus Vaccines, Envelope Glycoprotein, Ebola Virus
- Trial name
- NCT00374309
- Testing
- VRC-EBOADV018-00-VP
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Wound Infection
Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.
The aim of this study is to determine whether vancomycin with cefazoline is superior to vancomycin with placebo in preventing gastrostomy-related wound infection in carriers of methicillin-resistant staphylococcus aureus (MRSA).
- Trial name
- NCT00150852
- Testing
- Vancomycin
- Where
- 3 sites in France, Switzerland
- Volunteers
- 96 people
- Sponsor
- University Hospital, Geneva
HIV-1
Preventing Childhood HIV: Rescue Intervention. ANRS 12388 PREVENIR-PEV
The second visit of the Expanded Programme of Immunization when the child is 2 months old (EPI-2) represents a unique opportunity to link the EPI and PMTCT programmes and to introduce preventive and therapeutic rescue…
- Trial name
- PREVENIR-PEV (NCT03869944)
- Testing
- Lamivudine Oral Solution
- Where
- Burkina Faso
- Volunteers
- 97 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Pancreatitis, Acute Necrotizing
Thymosin Alpha 1 in the Prevention of Pancreatic Infection Following Acute Necrotizing Pancreatitis
Infected pancreatic necrosis and its related septic complications are the major cause of death in patients with acute pancreatitis, therefore prevention of pancreatic infection is of great clinical value in the treatment of AP.
- Trial name
- TRACE (NCT02473406)
- Testing
- Thymosin Alpha 1, normal saline
- Where
- 2 sites in China
- Volunteers
- 508 people
- Sponsor
- Weiqin Li
Skin Colonization, Catheterization
Antiseptic Use and Dressing Application
The purposes of the study are: 1. To compare the local efficacy (skin colonization) of 2 commercialized antiseptics used for the disinfection of the dressing application for an epicutaneocavous catheter (EPI). 2.
- Conditions
- Skin Colonization, Catheterization, Bacterial Infection
- Trial name
- NCT00389558
- Testing
- disinfection efficacy using Biseptine, disinfection efficacy using Amukin
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Maternite Regionale Universitaire
Measles
A Measles, Mumps, and Rubella Investigational Vaccine Trial (V205C-010)(COMPLETED)
The purpose of this study is to test the safety of a measles, mumps, and rubella study vaccine made from a new measles stock seed (a component of the vaccine made in 2003) with rHA (recombinant human albumin).
- Trial name
- NCT00109278
- Testing
- V205C, measles, mumps, and rubella virus vaccine live, Comparator: Measles, Mumps, and Rubella Virus Vaccine Live
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cytomegalovirus Infections, Kidney Transplant Infection
Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients
This study is designed to assess how effective letermovir is in preventing recurrence of cytomegalovirus (CMV) infection in adult kidney or kidney/pancreas transplant recipients who are UW Health patients.
- Conditions
- Cytomegalovirus Infections, Kidney Transplant Infection, Pancreas Transplant
- Trial name
- NCT06407232
- Testing
- Letermovir
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Wisconsin, Madison
HIV Infection
MAPS PrEP Van Study
For this study the investigators aim to see if giving participants an oral HIV prevention medication on a medical van, is a good option of care for individuals who inject drugs and/or are sexually active and therefore at a higher…
- Trial name
- MAPS PrEP (NCT06908252)
- Testing
- Pre-Exposure Prophylaxis (PrEP)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Duke University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.