Clinical trials: Infection Surgical Wound
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Surgical Site Infection
Incisional Negative Pressure Wound Therapy in Patients Undergoing Spine Surgery
Introduction: Posterior post-operative spine wounds involving surgery at multiple levels are known to have higher rates of wound complications relative to other areas of the body.
- Trial name
- NCT03820219
- Testing
- Prevena™ system, Standard sterile wound dressing
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Nova Scotia Health Authority
Surgical Site Infection, Post-Op Complication
Perioperative Immunonutrition in Patients Undergoing Gynecologic or General Elective Surgery (PURPOSE)
The objective of the implementation pilot is to assess the practicality of introducing a perioperative immunonutrition protocol into a hospital environment as well as a true measure of impact on the rate of surgical site…
- Trial name
- PURPOSE (NCT04057092)
- Testing
- Dietary Supplement INergy-FLD
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Surgical Wound Infection, Head and Neck Neoplasms
Prophylactic Antibiotic Duration in Head and Neck Cancer Surgery (PROTECT-HN Trial)
The goal of this clinical trial is to learn whether giving antibiotics for 7 days after surgery, instead of the usual 24 hours, lowers the chance of wound infection in adults having major surgery for mouth or throat cancer.
- Conditions
- Surgical Wound Infection, Head and Neck Neoplasms, Oral Cancer Neoplasms, Pharyngeal Neoplasms
- Trial name
- PROTECT-HN (NCT07851857)
- Testing
- Ampicillin/Sulbactam 24-Hour Postoperative Prophylaxis, Ampicillin/Sulbactam 7-Day Postoperative Prophylaxis
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- AC Camargo Cancer Center
Surgical Site Infection
Effect of Prophylactic Prosthesis Placement With Versus Without Omega-3 at the Umbilical Trocar Level on Surgical Site Infection and Herniation After Laparoscopic Cholecystectomy in Patients With Risk Factors.
TITLE: Effect of prophylactic prosthesis placement with versus without omega-3 at the umbilical trocar level on surgical site infection and herniation after laparoscopic cholecystectomy in patients with risk factors.
- Trial name
- NCT04345809
- Testing
- MESH WHIT OMEGA-3, MESH WITHOUT OMEGA-3
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical
Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical, Dehiscence of Laparotomy Wound, Suture, Interrupted
- Trial name
- NCT07241507
- Testing
- Continuous suturing, Interrupted suturing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Allama Iqbal Teaching Hospital
Cesarean Section Complications, Wound Breakdown
Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery
This will be an open label pilot randomized controlled clinical trial. Women undergoing cesarean delivery will be randomized to have standard wound dressing care or chlorohexidine gluconate (CHG) impregnated wound dressing…
- Conditions
- Cesarean Section Complications, Wound Breakdown, Wound Infection, Satisfaction
- Trial name
- NCT03887299
- Testing
- ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG), Standard Wound Care
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Surgical Wound Infection, Infection; Cesarean Section
Intervention for Postpartum Infections Following Caesarean Section
The purpose of this study is to examine whether Negative Pressure Wound Therapy is an effective wound treatment compared to conventional wound treatment in the period of time from reoperation to re-suturing in women having…
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Cesarean Section; Dehiscence, Complications; Cesarean Section
- Trial name
- APIPICS (NCT01891006)
- Testing
- Negative Pressure Wound Therapy, Standard wound dressing
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Odense University Hospital
Appendicitis
Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Appendectomy
This is a prospective trial of single incision versus standard 3-port laparoscopic appendectomy. The hypothesis is that there may a difference in wound infection rates, operative time, doses of analgesics post-operatively, and…
- Trial name
- NCT00981136
- Testing
- Single Incision Laparoscopic Appendectomy, 3 port laparoscopic appendectomy
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Children's Mercy Hospital Kansas City
Surgical Wound Infections, Colorectal Surgery
Subcuticular Continuous Suture Versus Skin Staples to Reduce Surgical Site Infections in Colorectal Surgery Patients
A comparison of skin closure techniques (standard skin closure with staples versus a continuous (subcuticular) absorbable suture), to determine if this changes the rate of post operative wound infections in elective colorectal…
- Trial name
- NCT02143336
- Testing
- subcuticular suture, Skin staples
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Postoperative Wound Infection
Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection?
Countless children undergo surgery annually for management of what clinicians consider to be a "dirty wound". One frequently encountered example is the ostomy reversal.
- Trial name
- NCT01691352
- Testing
- Wick dressing, No Wick
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta
Incisional Hernia, Ventral Hernia
Risk Factors for Mesh Infection After Abdominal Wall Reconstruction
Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging…
- Conditions
- Incisional Hernia, Ventral Hernia, Parastomal Hernia, Abdominal Wall Defect
- Trial name
- NCT07725718
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Minia University
Cardiac Surgery
Prevention of Surgical Wound Infection
To compare cost effectiveness of a polyurethane dressing or a vacuum therapy dressing versus the conventional gauze in the prevention of superficial wound infection y major cardiac surgery
- Trial name
- NCT03905213
- Testing
- dressing MEPORE, dressing MEPILEX, dressing PICCO
- Volunteers
- 900 people
- Sponsor
- Maria Jesus Perez
Colorectal Surgery
Safety and Efficacy of One Dose Prophylactic Antibiotic in Laparoscopic Colorectal Surgery
In colorectal surgery, the use of prophylactic antibiotics is recommended. The standard use of antibiotics for colorectal surgery is three doses.
- Trial name
- NCT01220661
- Testing
- Cefotetan
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- National Cancer Center, Korea
Postoperative Complications, Postoperative Wound Infection
Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates
Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries.
- Conditions
- Postoperative Complications, Postoperative Wound Infection, Pneumonia
- Trial name
- NCT03174223
- Testing
- deep neuromuscular block
- Where
- Netherlands
- Volunteers
- 460 people
- Sponsor
- Leiden University Medical Center
Complication of Surgical Procedure
TCOT Effectiveness in Preventing Wound Infections in Perineal Resections
In colorectal surgery, oxygen insufflation (which leads to higher oxygen concentration in the surgical site) has been shown to decrease infection rate.
- Trial name
- NCT02374294
- Testing
- Epiflo
- Sponsor
- Neogenix, LLC dba Ogenix
Surgical Wound, Revision Total Knee Arthroplasty
Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty
This study evaluates surgical site complications in subjects undergoing revision of a total knee arthroplasty when closed incision negative pressure therapy is used to manage the closed incision, as compared to a standard of care…
- Conditions
- Surgical Wound, Revision Total Knee Arthroplasty, Wounds and Injuries, Joint Disease
- Trial name
- PROMISES (NCT03274466)
- Testing
- Closed Incision Negative Pressure Therapy (ciNPT), Standard of Care Dressing
- Where
- 17 sites in United States
- Volunteers
- 294 people
- Sponsor
- KCI USA, Inc
Skin Cancer
ObservAtional Study to Investigate Surgical Site Infection in Ulcerated Skin Cancers
The investigators aim to recruit 311 participants to this study from three UK Dermatology departments. The investigators will invite people with suspected skin cancers whose lesions have a broken surface (also known as ulcerated)…
- Trial name
- OASIS (NCT03782727)
- Where
- 3 sites in United Kingdom
- Volunteers
- 148 people
- Sponsor
- Cardiff and Vale University Health Board
Infection, Surgical Site
Negative Pressure Therapy After Infected Mesh Removal.
Chronic mesh infection mesh is a complication with leads to a long hospital stays, reoperation and admissions through emergency department.
- Trial name
- ICROMA (NCT05247086)
- Testing
- Negative pressure therapy
- Volunteers
- 94 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Septicemia
Correlating MicroRNA Changes With Sepsis Outcomes
This trial studies how changes in microRNAs may correlate with sepsis outcomes. Sepsis is a type of severe infection of the blood stream, and its diagnosis may be obscured by many other conditions such as surgery, trauma, and…
- Trial name
- NCT03929159
- Testing
- Biospecimen Collection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M.D. Anderson Cancer Center
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