Clinical trials: Infection Wound
Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Membrane Oxygenation
Personalized Ventilator Settings for Patients on ECMO
While mechanical ventilation can be used to sustain life in those with lung injury, it, can further worsen lung injury or prevent lung healing resulting in high morbidity and mortality as seen in Acute Respiratory Distress…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Membrane Oxygenation, Respiratory Failure Patients Treated With ECMO, Respiratory Failure, ICU
- Trial name
- PEEPECMO (NCT07673250)
- Testing
- Personalized Positive End-Expiratory Pressure (PEEP)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, San Diego
Surgical Site Infection, Surgical Wound
Optimizing Closed Incision Negative Pressure Wound Therapy in Emergency Laparotomy
The purpose of this study is to find differences in rates of surgical site infections following emergency laparotomy with the use of two different incisional negative pressure wound therapy (iNPWT)devices.
- Conditions
- Surgical Site Infection, Surgical Wound, Surgical Wound Infection, Surgical Complication
- Trial name
- OPTIWOUND (NCT05716490)
- Testing
- Incisional negative pressure wound therapy, Control group - standard wound dressing
- Where
- Portugal
- Volunteers
- 114 people
- Sponsor
- Centro Hospitalar do Tâmega e Sousa
Corneal Perforation, Exposure Keratitis
The Role of OmniLenz® in the Treatment of Small Corneal Perforations Secondary to Exposure Keratitis in ICU Patients
Case series of 5 ICU patients in Farwaniya Hospital who developed exposure keratitis and a subsequent small corneal perforation between April 2022 and April 2024.
- Conditions
- Corneal Perforation, Exposure Keratitis, Infectious Keratitis
- Trial name
- NCT06539663
- Testing
- OmniLenz®
- Where
- Kuwait
- Volunteers
- 5 people
- Sponsor
- Farwaniya Hospital
Bladder Infections and Inflammations
Chronic Indwelling Foley and Catheter Associated Trauma (CIF-CAT) Study
To determine whether an indwelling low profile Kohli Atraumatic Catheter causes less macro-morphologic inflammation and edema to the bladder mucosa than a traditional indwelling Foley catheter as assess by computerized image…
- Trial name
- NCT03790826
- Testing
- cystoscopy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nellie Medical, LLC
Surgical Site Infection
Investigation of Environmental Parameters in Operating Rooms
Postoperative surgical site infection (SSI) is a serious and complicated healthcare-associated infection (HAI) affecting about 2% of patients undergoing orthopedic surgery.
- Trial name
- NCT05816135
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Sahlgrenska University Hospital
HIV Infections
Trauma-informed Care for Youth With HIV in Memphis
Enhanced interventions are needed to mitigate the impact psychological trauma has on HIV appointment adherence among Black youth with HIV in the Southern United States (U.S.).
- Trial name
- NCT07137026
- Testing
- Personnel intervention and patients
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Wound Debridement
A Comparative Study of the Efficacy and Safety of Two Methods in the Treatment of Skin Wounds
This study will compare the experimental group (debridement assisted by surgical microscope + VSD) and the control group (debridement under naked-eye observation + VSD) in terms of the rate of change in BWAT scores at one week…
- Trial name
- NCT07323615
- Testing
- microscopic
- Volunteers
- 98 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Surgical Wound Infection
Prospective Cohort Study in Evaluation of Risk Factors for Infection During and After Coronary Graft Operations.
We aim to prospectively evaluate the risk factors that can play a role before, during or after the surgical period.
- Trial name
- NCT04258878
- Testing
- Sternotomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Surgical Site Infection
The Use of 2% Chlorhexidine Gluconate Impregnated Cloth Bathing in Preoperative Skin Preparation
To compare the use of towels impregnated with 2% chlorhexidine gluconate in the traditional preoperative bath with 2% chlorhexidine gluconate in preventing the occurrence of surgical site infection among patients undergoing…
- Trial name
- NCT03813693
- Testing
- towels impregnated with 2% chlorhexidine gluconate, chlorhexidine gluconate 2% liquid
- Where
- Brazil
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Wound Heal
Electroceutical Dressing Technology (EDT) Against Wound Microbial Biofilm Infection
There are currently limited treatments available that show anti-biofilm efficacy for wound infection management Biofilms account for over 80% of infections and approximately 65% of nosocomial infections caused by microorganisms…
- Trial name
- EDT BioFilm (NCT04794621)
- Testing
- Electroceutical Dressing Technology-EDThi, Adding EDTlo (Procellera®) for 3 weeks after use of EDThi
- Where
- 3 sites in United States
- Volunteers
- 112 people
- Sponsor
- Indiana University
Hypothermia, Hemorrhage, Postpartum
Complications Associated With Intraoperative Hypothermia.
Maintaining intraoperative normothermia and temperature measurement is a marker of quality of care. We know that intraoperative hypothermia is associated with an increased risk of cardiovascular events, infection of the surgical…
- Conditions
- Hypothermia, Hemorrhage, Postpartum, Infection Surgical Wound, Transfusion-dependent Anemia
- Trial name
- NCT05203016
- Testing
- Hipotermia/Normotermia
- Where
- Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Cervical Cancer, Uterine Cervical Neoplasm
Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer
During radiation therapy (RT) to pelvic tumors, the small intestine, colon and rectum are inevitably included in the radiation field and are healthy tissues that suffer damage as an adverse effect.
- Conditions
- Cervical Cancer, Uterine Cervical Neoplasm, Pelvic Inflammatory Disease, Radiation Toxicity
- Trial name
- NCT03994055
- Testing
- Omega-3 fatty acids, Antioxidants, Soluble fiber
- Where
- Mexico
- Volunteers
- 136 people
- Sponsor
- National Institute of Cancerología
Surgical Site Infection
Effect of Vitamin E Ointment on Incisional SSI in Colorectal Surgery
A prospective, randomized study was performed. The patients were randomized into 2 groups: those patients undergoing subcutaneous vitamin E ointment application (Group 1) and those patients who not (Group 2).
- Trial name
- NCT02820948
- Testing
- Vitamin E ointment application
- Volunteers
- 108 people
- Sponsor
- Hospital General Universitario Elche
Surgical Wound Infection, Heart; Surgery, Heart, Functional Disturbance as Result
Early Detection of Surgical Wound Infections Using Sensor Technology
Infections that are caused by surgical incision are commonly known as surgical site infections (SSI). A surgical wound infection can develop at any time after surgery until the wound has healed (usually two to three weeks after…
- Trial name
- SSI-Sensor (NCT03401658)
- Testing
- Sensor light detector
- Where
- United Kingdom
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Coronavirus Infection, Multi-Organ Disorder
Capturing MultiORgan Effects of COVID-19
The C-MORE study is prospective observational holistic longitudinal study which will characterise the prevalence of multi-organ injury among COVID-19 survivors post hospital discharge and assess its effects on quality of life…
- Trial name
- C-MORE (NCT04510025)
- Testing
- Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Surgical Site Infection, Capsular Contracture Associated With Breast Implant
Postoperative Antibiotics Following Primary and Secondary Breast Augmentation
Postoperative antibiotics are routinely used for implant-based breast augmentation at the investigators' institution. From 2017-2019, the investigators' institution has conducted approximately 270 primary and secondary breast…
- Conditions
- Surgical Site Infection, Capsular Contracture Associated With Breast Implant, Antibiotic Resistant Infection, Antibiotic Side Effect
- Trial name
- NCT04834310
- Testing
- Cefazolin, Cephalexin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Surgical Wound Infection
Prevention of Surgical Site Infections
The primary research question is whether interventions to prevent caregiver and system errors will increase the proportion of laparotomy patients who receive recommended measures to prevent surgical site infections.
- Trial name
- NCT00353613
- Testing
- Package of targeted interventions to reduce error
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- The University of Texas Health Science Center, Houston
Multiple Sclerosis, Relapsing-Remitting
A Post-Authorization, Long-term Study of Ozanimod Real-world Safety
The purpose of this study is to determine the rates of adverse events of interest (AEIs) in a real-world population of participants with relapsing remitting multiple sclerosis (RRMS) receiving Ozanimod, sphingosine-1 phosphate…
- Trial name
- ORION (NCT05605782)
- Where
- United States
- Volunteers
- 9,000 people
- Sponsor
- Bristol-Myers Squibb
Tick Bites, Tick-borne Diseases
Tick-borne Illness and Clothing Study of Rhode Island
Lyme and other tick-borne diseases pose a significant health threat to outdoor workers. This study is a double-blind randomized controlled trial of outdoor workers in Rhode Island and the surrounding area that will address the…
- Trial name
- NCT02613585
- Testing
- Permethrin Impregnated Clothing
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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