Clinical trials: Infection Wound
Patients Undergoing Hepatopancreatobiliary Surgery
Negative Pressure Wound Therapy to Reduce Surgical Site Infection
The purpose of this study is to compare the rate of surgical site infection between traditional wound care and negative pressure wound therapy.
- Trial name
- NCT01905397
- Testing
- Conventional wound therapy, Negative pressure wound therapy
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Duke University
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections
Postpartum infection if a major cause of maternal morbidity and mortality and surgical site infections are some of the common complications following cesarean section.
- Conditions
- Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
- Trial name
- NCT05392400
- Testing
- Steri3X, Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Acquired Brain Injury, Comparative Effectiveness Research
Efficacy of EFA in Acquired Brain Injury
Acquired brain injury (ABI) is one of the biggest cause of death and disability in the world. Patients with ABI often have difficulties with swallow and breath.
- Conditions
- Acquired Brain Injury, Comparative Effectiveness Research, Lung Diseases, Obstructive
- Trial name
- NCT05993364
- Testing
- Free Aspire with Expiratory Flow Accelerator (EFA) technology, In-Exufflator Machine, Traditional respiratory treatment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
COVID -19, Acute Kidney Injury
Acute Kidney Injury in Critical COVID-19: Outcomes and Risks
This retrospective observational study aims to determine the incidence of acute kidney injury (AKI) associated with COVID-19, risk factors, and effects on mortality for intensive care unit patients.
- Conditions
- COVID -19, Acute Kidney Injury, Intensive Care Unit (ICU) Admission, Mortality
- Trial name
- NCT07089693
- Where
- Turkey (Türkiye)
- Volunteers
- 238 people
- Sponsor
- Ankara University
Surgical Site Infection
The Impact of Using Triclosan-antibacterial Sutures on the Incidence of Surgical Site Infection
To compare conventional polyglactin 910 sutures with triclosan-coated polyglactin 910 antimicrobial sutures for the reduction of surgical site infections and any associated health and economic benefits.
- Trial name
- NCT01019447
- Testing
- Vicryl Plus, Vicryl
- Where
- 2 sites in Egypt
- Volunteers
- 701 people
- Sponsor
- Cairo University
Common Bile Duct Injury
Post-cholecystectomy Major Bile Duct Injury
Bile duct injury (BDI) is one of the devastating recognized complications of cholecystectomy which does not respect the seniority or experience of the surgeon.
- Trial name
- NCT05436626
- Testing
- Early BDI reconstruction without abdominal sepsis control, Early BDI reconstruction with abdominal sepsis control, Delayed reconstruction
- Volunteers
- 277 people
- Sponsor
- South Valley University
Community-acquired Methicillin-resistant Staphylococcus Aureus Infection
New Mexico Honey Wound Treatment Research Study
In a time of emerging bacteria that are resistant to antibiotics, honey offers an alternative that has potential to reduce the heavy reliance on pharmaceutical antibiotics.
- Trial name
- NCT01748318
- Testing
- New Mexico Honey, Bactrim DS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- R. Stephen Rankin, M.D.
Sepsis
PyroEVs/PLIN3 Mediate Lipid Droplet-Mitochondrial Coupling in Sepsis Endothelial Injury
Objective: To investigate the correlation of PyroEVs and PLIN3 with the severity and prognosis of sepsis patients. Participants: Sepsis patients meeting the Sepsis 3.0 diagnostic criteria admitted to the Intensive Care Unit of…
- Trial name
- NCT07727265
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Covid19, Mental Health Disorder
MIND/COVID-19: Mental Health Impact and NeeDs Associated With COVID-19: a Comprehensive National Evaluation in Spain
The aim of the proposed project is to provide a comprehensive assessment of the mental health impact of the ongoing COVID-19 outbreak in Spain.
- Conditions
- Covid19, Mental Health Disorder, Mental Health Conditions
- Trial name
- NCT04556565
- Where
- 18 sites in Spain
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Jordi Alonso
COVID19, Acute Renal Failure
The Effect of the Severity of COVID-19 Disease on the Incidence of Acute Renal Failure in ICU
Aim of the study is to determinate the frequency of acute renal failure in COVID-19 patients, its relationship with the severity of COVID-19 disease in ICU, and the ability to take precautions against these factors.
- Trial name
- NCT04799600
- Testing
- BRESCİA-COVİD Respiratory Severity Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Shock, Septic, Renal Failure, Acute
Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care)
Sepsis and septic shock are still important causes of mortality in intensive care medicine. Renal replacement therapy by standard volume haemofiltration is currently used, but a higher-volume haemofiltration may improve the…
- Trial name
- IVOIRE (NCT00241228)
- Testing
- Venovenous haemofiltration (renal replacement therapy)
- Where
- 16 sites in Belgium, France and 1 more
- Volunteers
- 139 people
- Sponsor
- University Hospital, Bordeaux
Gut Microbiota, Intra-abdominal Infections
Gut Microbiota Analysis in IAI Patients With Sepsis-associated Liver Dysfunction
With the rapid development of intensive care medicine, the mortality of patients with sepsis has decreased over the past decade, but it is still the leading cause of death in intensive care unit (ICU).
- Conditions
- Gut Microbiota, Intra-abdominal Infections, Acute Gastrointestinal Injury, Sepsis-associated Liver Dysfunction
- Trial name
- 2022-11-09 (NCT05628493)
- Testing
- Gut microbiota Analysis
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese Medical Association
Wound Healing Disturbance of Port-A
Using a Thermal Imaging System to Evaluate the Wound of Port-A and the Relationship Between Thermal Images and Infection
Permanently implantable venous ports (Port-A) is very important to patients receiving chemotherapy. It not only provides a reliable route to administrate intravenous drugs, and it also requires minimal care when it is not in use.
- Trial name
- NCT02072265
- Testing
- Infrared thermal images
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Surgical Site Infection, Surgical Wound Infection
Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections
A Randomized controlled trail to To assess the efficacy of povidone-iodine wash before wound closure in preventing surgical site infections.
- Trial name
- NCT05077592
- Testing
- 10% Povidone Iodine
- Where
- Egypt
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Site Infection
One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection
The purpose of this study is to compare the outcomes of two different treatment options commonly used to manage periprosthetic joint infection (PJI), an infection around the artificial knee or hip.
- Trial name
- NCT02734134
- Testing
- One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
- Where
- 5 sites in United States
- Volunteers
- 343 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Wound Surgical, Wound Infection
PINTA - Prophylactic Incisional Negative Pressure Therapy for Major Amputations
Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. This study is taking place to investigate if Negative Pressure Wound Therapy (NPWT) dressings reduces Surgical Site Infections, post…
- Conditions
- Wound Surgical, Wound Infection, Cosmesis
- Trial name
- PINTA (NCT06025253)
- Testing
- Negative Pressure Wound Therapy, Standard Wound Dressing
- Where
- 7 sites in Ireland
- Volunteers
- 728 people
- Sponsor
- Royal College of Surgeons, Ireland
Amputations for Management of Sarcoma,Trauma,or Chronic Infection
Quality of Life in Amputated Patients Based on Social Deprivation Factors
The purpose of this study is to investigate the quality of life in patients who previously underwent major amputation, and to determine any correlation with social deprivation factors.
- Trial name
- NCT06205745
- Where
- United States
- Sponsor
- University of Florida
Wound Healing, Wound Infection
Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on Thigh
This study aims to compare the effectiveness of two wound dressings, Acticoat Absorbent (AA) and BCT Antimicrobial (BCT) on Split Thickness Skin Graft (STSG) donor site.
- Conditions
- Wound Healing, Wound Infection, Pain, Pruritus
- Trial name
- NCT01769144
- Testing
- Acticoat Absorbent, BCT
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Obstruction, Cancer
Intravenous Nutrition in Hospitalized Patients: Comparison of Two Oils
Intravenous nutrition is an important therapy for the recovery of many patients. It is indicated when the patients cannot take food by mouth or use their intestines for feeding.
- Conditions
- Obstruction, Cancer, Ileus, Malnutrition
- Trial name
- NCT01943409
- Testing
- Intralipid, ClinOleic
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Johane Allard
Acute Kidney Injury, Septic Shock
Macro and Micro Haemodynamic Responses to Shock in the Renal and Systemic - MICROSHOCK - RENAL
An observational study of the state of the renal and systemic circulations in patients with early septic shock. Both macro and microvascular parameters will be assessed using echocardiography, sublingual incident dark field…
- Trial name
- NCT03713307
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College London
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.