Clinical trials: Infection Wound
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS: Stress Reduction for Refugees
The COVID-19 pandemic crisis is associated with a wide range of stressors for the general population. For forcibly displaced persons (FDPs), the turmoil of this crisis is magnified significantly, and elevated pre-existing…
- Trial name
- NCT04761510
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Geriatric Presentation of Urinary Tract Infection, Acute Kidney Injury
Intraoperative NGAL Level in Geriatric Patients Undergoing Laparotomy
The aim of this study is to detect early renal dysfunction that may occur during the surgical procedure in geriatric patients who will undergo laparotomy surgery.
- Trial name
- NCT05030727
- Testing
- record of pNGAL
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Surgical Site Infection
Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection
Surgical site infections (SSI) are the most common healthcare-associated infections and sources of morbidity and over-mortality.
- Trial name
- NCT06108791
- Testing
- FIO2=0.8, FIO2=0.33
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Assiut University
Covid19
COVID-19 Soliris Expanded Access Protocol
This protocol provides participants with COVID-19 access to Soliris.
- Trial name
- NCT04802083
- Testing
- Eculizumab
- Sponsor
- Alexion Pharmaceuticals, Inc.
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Wound Infection
To Assess Use of Vancomycin Powder in Craniotomy on Wound Infection Rates
Surgical site infection (SSI) after craniotomy is a major cause of morbidity and mortality besides its major health care cost. In each hospital, all measures are taken to decrease SSI.
- Trial name
- NCT04917627
- Testing
- Vancomycin
- Where
- Qatar
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hamad General Hospital
Surgical Site Infection
AO Multicenter Intervention Trial for Prevention of Surgical Site Infection
This study is designed to collect data from 8,476 fracture patients during a pre-and post-intervention phases of two years length each. The intervention consists on the implementation of the AOT SSI Prevention Bundle. D
- Trial name
- AOPOSSI (NCT03380273)
- Testing
- Implementation of the AO Trauma SSI Prevention Bundle
- Where
- 14 sites in United States, Argentina and 4 more
- Volunteers
- 222 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Postoperative Wound Infection Superficial Incisional, Postoperative Wound Infection Deep Incisional Surgical Site
Is the NPWTi Better Than the Conventional NPWT
The goal of this clinical trial is to compare the effectiveness of NPWTi and NPWT in superficial and deep surgical site infections using an improvised system with continuous lavage with saline and chlorhexidine.
- Trial name
- NCT06014788
- Testing
- NPWTi, Conventional NPWT
- Where
- Bulgaria
- Volunteers
- 100 people
- Sponsor
- Military Medical Academy, Bulgaria
Bacterial Infections, Antibiotic Resistant Infection
Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan
The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.
- Conditions
- Bacterial Infections, Antibiotic Resistant Infection, Surgical Site Infection
- Trial name
- NCT05106803
- Testing
- ciprofloxacin
- Where
- Jordan
- Volunteers
- 24 people
- Sponsor
- Yarmouk University
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
COVID-19, Psychological Distress
Psychological Impact of COVID-19 on Intensive Care Survivors
Psychological distress is commonly experienced by survivors of an intensive care admission, including patients treated during previous pandemics.
- Conditions
- COVID-19, Psychological Distress, Depression, Anxiety
- Trial name
- PIM-COVID (NCT05092529)
- Where
- 50 sites in United Kingdom
- Volunteers
- 1,620 people
- Sponsor
- Royal Liverpool University Hospital
Sepsis
EARLY-MYO-SEPSIS Registry
The diagnosis and pathophysiology of sepsis-induced cardiac dysfunction remain unknown. This registry is to evaluate characteristics of sepsis patients by multi-modalities imaging, including echocardiography, cardiovascular…
- Trial name
- NCT04513795
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Sepsis, Acute Kidney Injury
Efficacy of Online Hemodiafiltrationlysis in Cytokine Removal
Following the concept of "peak concentration hypothesis", which suggest the cutting peak of pro- and anti-inflammatory mediators would result in restoring a situation of immunohomeostasis.
- Trial name
- NCT01791712
- Testing
- On-line hemodiafiltration, High-flux Hemodialysis
- Where
- Thailand
- Volunteers
- 28 people
- Sponsor
- Chulalongkorn University
Wound Infection
Randomized Trial to Assess PO Versus IV Antibiotics
The goal of this study is to evaluate the effect of treatment of post-op wound infection in long bones after fracture fixation or joint fusion and either: (Group 1) operative debridement and PO antibiotic treatment for 6 weeks…
- Trial name
- POvIV (NCT01714596)
- Testing
- PO versus IV antibiotics Route of administration evaluation
- Where
- 24 sites in United States
- Volunteers
- 233 people
- Sponsor
- Major Extremity Trauma Research Consortium
Low Gelsolin, Trauma
Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels
This study is designed to assess the pharmacokinetics and safety of an infusion of a single dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the Intensive Care Unit with documented low levels…
- Conditions
- Low Gelsolin, Trauma, Infection, Burns
- Trial name
- NCT00671307
- Testing
- rhu-pGelsolin
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Critical Biologics Corporation
Intensive Care Unit, Intraventricular Hemorrhage
Prediction of Undesired Obstruction in External Ventricular Drains.
Acute obstructive hydrocephalus often complicates intraventricular hemorrhage (IVH). The insertion of an external ventricular drain (EVD) is typically necessary in order to alleviate intracranial pressure by draining excess…
- Conditions
- Intensive Care Unit, Intraventricular Hemorrhage, External Ventricular Drain
- Trial name
- EVD-OBS (NCT06466811)
- Testing
- Patients of intensive care unit, Patients of surgical intensive care unit
- Where
- France
- Volunteers
- 640 people
- Sponsor
- Nantes University Hospital
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Infection Rates Between Primary Wound-closure (Allgower) and Secondary Wound Healing After Removal of an External Fixator
Wound Closure (Allgower) Versus Secondary Open Wound Healing After Removal of the External Fixator
In this prospective randomized controlled single-center trial, based on a non-inferiority design, the outcome of the treatment of patients are analyzed, whereas in half of the cases the wounds are left open and the other ones are…
- Trial name
- Pinsides (NCT03842956)
- Testing
- Primary wound closure in Allgower Technique vs. secondary open wound healing of pin-sides after removal of the fixated-externe
- Where
- Switzerland
- Volunteers
- 241 people
- Sponsor
- Luzerner Kantonsspital
Neurologic Disorder, Stroke
Home Based Tele-exercise for People With Chronic Neurological Impairments
To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health and wellness in people with chronic neurological impairments (CNI).
- Conditions
- Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- Telex (NCT04564495)
- Testing
- Seated exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Burke Medical Research Institute
Septic Shock, Stress Response
Effect of Dexmedetomidine vs Esmolol or Placebo on Cerebral Hemodynamics in Septic Shock
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Some researchers proposed that the dysregulated response or organ dysfunction can be lessened by reducing the stress…
- Conditions
- Septic Shock, Stress Response, Cerebral Hemodynamics
- Trial name
- NCT06169475
- Testing
- Dexmedetomidine Hydrochloride, Esmolol Hydrochloride
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Xinchen Wang
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