Clinical trials: Infection of Bloodstream
Bloodstream Infection, Pneumonia, Bacterial
Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients
DETERMINE trial is a prospective multicenter multinational cohort study. This study will be carried out to predict the risk of bloodstream infections (BSIs) or other types of invasive infection with carbapenem resistant…
- Conditions
- Bloodstream Infection, Pneumonia, Bacterial, Intra-abdominal Infection, Urinary Tract Infections
- Trial name
- DETERMINE (NCT04229511)
- Testing
- Detection of CRKp colonization
- Where
- Turkey (Türkiye)
- Volunteers
- 520 people
- Sponsor
- SCARE (Study group for carbapenem resistance)
Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection
Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery
Randomized controlled trial comparing femoral vs internal jugular insertion site of central venous catheters (CVC) in newborns and infants undergoing cardiac surgery.
- Conditions
- Central Line-associated Bloodstream Infection (CLABSI), Central Venous Catheter Associated Bloodstream Infection, Heart; Surgery, Heart, Functional Disturbance as Result, Congenital Heart Disease
- Trial name
- PRECiSE (NCT03282292)
- Testing
- Internal jugular vein CVC insertion
- Where
- Italy
- Sponsor
- IRCCS Policlinico S. Donato
Artificial Intelligence, Central Venous Catheter Associated Bloodstream Infection
Artificial Intelligence With Determination of Central Venous Catheter Line Associated Infection Risk
The goal of this methodological, retrospective and prospective study is to; it is a tool to develop a risk estimator tool to detect risk gaps in individuals using artificial intelligence technology that is dangerous for those…
- Trial name
- NCT05914571
- Volunteers
- 2,000 people
- Sponsor
- Saglik Bilimleri Universitesi
Kidney Failure, Chronic, Catheter-Related Infections
Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection
The purpose of this study is determine safety and effectiveness of Neutrolin, a catheter lock solution, for prevention of central venous catheter associated bloodstream infection in hemodialysis patients.
- Trial name
- NCT02651428
- Testing
- Neutrolin, Heparin
- Where
- 5 sites in United States
- Volunteers
- 806 people
- Sponsor
- CorMedix Therapeutics
Bacteremia, Gram-Positive Bacterial Infections
Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections
This study will treat hemodialysis patients who have a central catheter that is thought to be infected with a specific bacteria (Gram positive bacteria).
- Trial name
- NCT00108433
- Testing
- Cefazolin IV, Linezolid IV, Vancomycin (IV)
- Where
- 17 sites in United States, Colombia and 5 more
- Volunteers
- 61 people
- Sponsor
- Pfizer
Enterococcus Faecalis Infection, Blood Stream Infection
Antimicrobial Combination Therapy for Treatment of Enterococcus Faecalis Bacteremia
Prospective, multicenter, national, observational pharmacological study on the evaluation of efficacy of appropriate monotherapy vs combination treatment for non-complicated Enterococcus faecalis (EF) bloodstream infection (BSI)…
- Conditions
- Enterococcus Faecalis Infection, Blood Stream Infection, Gut Microbiomes
- Trial name
- MicroEFfAECT (NCT06833593)
- Where
- 4 sites in Italy
- Volunteers
- 510 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Relapsed Multiple Myeloma, Refractory Multiple Myeloma
INfections in Patients Treated With CAR-T
This study includes adults with multiple myeloma or B-cell lymphoma who were/will be treated with CAR-T cell therapy at the IRCCS Azienda Ospedaliero-Universitaria di Bologna.
- Conditions
- Relapsed Multiple Myeloma, Refractory Multiple Myeloma, B-Cell Non-Hodgkin Lymphoma, Bloodstream Infections
- Trial name
- IN-CART (NCT07713511)
- Where
- Italy
- Volunteers
- 290 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bloodstream Infection
Efficacy and Safety of 7 Versus 14 Days of Antibiotic Treatment for Pseudomonas Aeruginosa Bacteraemia
Phase IV, open-labeled, randomized and multicenter clinical trial to demonstrate the superiority of antibiotics with authorized indication for 7 days versus 14 days in the treatment of bloodstream infections produced by P.
- Trial name
- SHORTEN2 (NCT05210439)
- Testing
- Short-treatment of any active antibiotic regimen, Long-treatment of any active antibiotic regimen
- Where
- 37 sites in Spain
- Volunteers
- 306 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Sore Throat
Inhalation of Lidocaine Before Intubation
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
- Trial name
- NCT01838993
- Testing
- Lidocaine inhalation
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- New Taipei City Hospital
Cardiogenic Shock Acute, Bypass, Cardiopulmonary
Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock
Mixed cardiogenic-vasoplegic shock (M-CS) represents a distinct and severe phenotype of cardiogenic shock characterized by concomitant myocardial dysfunction and inappropriate systemic vasodilation.
- Conditions
- Cardiogenic Shock Acute, Bypass, Cardiopulmonary, Septic Shock, Mechanical Circulatory Support
- Trial name
- PROMIX (NCT07354568)
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Bloodstream Infection
Ethanol Locks for the Treatment of Central Venous Line Infections
Ethanol Locks as an Adjunct Treatment for Central Venous Line Infections Purpose To evaluate the effectiveness of a 70% ethanol lock solution when used as an adjunct therapy with antibiotics to treat central venous line…
- Trial name
- NCT00680459
- Testing
- 70% ethanol, heparin flush solution
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Baystate Medical Center
CLABSI - Central Line Associated Bloodstream Infection, Catheter-Related Blood Stream Infection
Study on the Reduction of Catheter-related Infections by Use of Self-disinfecting Venous and Arterial Access Caps
Observational study on the reduction of catheter-related Infections by use of self-disinfecting venous and arterial access caps (Curos caps ;3M, Saint Paul, MN, USA)
- Trial name
- STERILE (NCT04534348)
- Testing
- 70% isopropyl alcohol-impregnated catheter caps
- Where
- Germany
- Volunteers
- 598 people
- Sponsor
- University of Cologne
Catheter-related Bloodstream Infection
Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)
We proposed to perform a prospective randomized controlled trial to study the effect of the use of a commercially-available chlorhexidine-impregnated sponge (Biopatch) as part of central venous catheter care on catheter-related…
- Trial name
- NCT00548132
- Testing
- Chlorhexidine-impregnated foam dressing
- Where
- United States
- Volunteers
- 1,088 people
- Sponsor
- Washington University School of Medicine
Pulmonary Embolism, Medical Device Complication
Angel® Catheter Post Market Registry
This is a post-market, observational, retrospective multi-center Registry designed to gather information on the performance of the Angel® Catheter in general clinical practice.
- Conditions
- Pulmonary Embolism, Medical Device Complication, Deep Vein Thrombosis, Catheter Thrombosis
- Trial name
- NCT02917135
- Testing
- Angel® Catheter
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 2,000 people
- Sponsor
- BiO2 Medical
Beta Lactam Resistant Bacterial Infection, Enterobacteriaceae Infections
PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)
Data regarding optimal treatment for extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae blood-stream infection are lacking.
- Conditions
- Beta Lactam Resistant Bacterial Infection, Enterobacteriaceae Infections, Bacteremia
- Trial name
- PETERPEN (NCT03671967)
- Testing
- Piperacillin/tazobactam, Meropenem
- Where
- 14 sites in Canada, Israel
- Volunteers
- 1,084 people
- Sponsor
- Rambam Health Care Campus
Catheter-related Bloodstream Infection
SQ53 Disinfectant Wipes for Prevention of CRBSI
SQ53 is a novel antimicrobial, sporicidal solution that is based on a platform of quaternary ammonium chloride compounds. It has been tested against a wide range of bacteria, viruses, spores and fungal pathogens.
- Trial name
- NCT04822467
- Testing
- SQ53 Wipe, Ethanol Wipe
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- The Cleveland Clinic
Gram-negative Bacterial Infections
Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream Isolates
This research is important because it allows for the determination of resistance rates to antibiotics that may not be frequently tested by the clinical microbiology laboratory at University of Pittsburgh Medical Center…
- Trial name
- NCT00394784
- Where
- United States
- Sponsor
- University of Pittsburgh
Premature Intestinal Microbiota, Necrotizing Enterocolitis
Defining the Intestinal Microbiota in Premature Neonates
The investigators will collect daily faecal samples from premature (<32 weeks) infants in the intensive care unit from the day of birth until they are discharged.
- Conditions
- Premature Intestinal Microbiota, Necrotizing Enterocolitis, Late Onset Bloodstream Infection
- Trial name
- NCT01102738
- Where
- 3 sites in United Kingdom
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Central Line-Associated Bloodstream Infection
Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection
Use of long-term central venous access devices (including tunneled lines and ports) can be associated with development of bloodstream infection caused by build-up of bacteria or fungus on the inside of the device, called central…
- Trial name
- NCT01472965
- Testing
- ethanol
- Where
- 2 sites in United States, Australia
- Volunteers
- 95 people
- Sponsor
- St. Jude Children's Research Hospital
Skin and Soft Tissue Infections, Hiv
ASAP: Access to Syringes at Pharmacies for the Prevention of Bloodborne Infections Among People Who Inject Drugs
Access to Syringes at Pharmacies (ASAP) is a refinement of an evidence-based, pharmacy intervention to increase pharmacy-based sales of syringes to PWID in order to reduce bloodborne illnesses among them.
- Conditions
- Skin and Soft Tissue Infections, Hiv, Hepatitis C, Bloodstream Infection
- Trial name
- ASAP (NCT05270135)
- Testing
- ASAP
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Arizona