Clinical trials: Infections, Coronavirus
SARS-CoV-2 Infection
Microvascular Injury and Distal Thrombosis in COVID-19
Investigators aimed to better understand the pathophysiology of SARS-CoV-2 pneumonia in non-critically ill hospitalized patients secondarily presenting with clinical deterioration and increase in oxygen requirement
- Trial name
- MIND (NCT04990505)
- Testing
- lung ventilation/perfusion scintigraphy
- Where
- Monaco
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Princesse Grace
Post-COVID Condition, Long COVID
Long-Term Health Effects of Previous Coronavirus Disease 2019 (COVID-19) in Patients Undergoing Preoperative Anesthesia Evaluation
The Coronavirus Disease 2019 (COVID-19) pandemic has resulted in persistent health problems in a significant proportion of individuals after recovery from the acute infection.
- Conditions
- Post-COVID Condition, Long COVID, Sequelae of COVID-19
- Trial name
- NCT07435805
- Testing
- Post-COVID Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
SARS-CoV-2 Infection, COVID-19
A Study to Evaluate the Immunogenicity and Safety of a Recombinant Protein COVID-19 Vaccine in Population Aged ≥18 Years
The study is a randomized, double-blind, positive-controlled Phase II booster study. It will evaluate the immunogenicity and safety of SCTV01E compared with Comirnaty.
- Trial name
- NCT05329051
- Testing
- SCTV01E, Comirnaty
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Preventive Immunization COVID-19
An Open Study of the Safety, Tolerability and Immunogenicity of "Gam-COVID-Vac Lyo" Vaccine Against COVID-19
the purpose of this study: to evaluate the safety, tolerability and immunogenicity of the drug "Gam-COVID-Vac Lyo", a lyofilizate for preparing solution for intramuscular administration, at various times after vaccination in…
- Trial name
- NCT04437875
- Testing
- Gam-COVID-Vac Lyo
- Where
- Russia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
This is a Pilot Study Which Aims to Assess the Validity and Applicability of Lateral Flow Assays (LFAs) Which Can be Used as a Point of Care Test for COVID-19, Covid19
The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19
This is a pilot study which aims to assess the validity and applicability of lateral flow assays (LFAs) which can be used as a point of care test for COVID-19.
- Trial name
- LAVA (NCT04629157)
- Testing
- Innova Lateral Flow Device
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
COVID-19, Respiratory Failure
Characteristics and Outcomes of Patients With COVID-19 Treated With HFNO and Prone Positioning
A subset of patients with COVID-19 develops acute respiratory failure and acute respiratory distress syndrome (ARDS) (1). The use of invasive mechanical ventilation for the treatment of these conditions is associated with high…
- Conditions
- COVID-19, Respiratory Failure, Prone Position, Endotracheal Intubation
- Trial name
- AW-PP_Covid (NCT05178212)
- Where
- Argentina
- Volunteers
- 600 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Covid-19
Effects of Face Masks on Cardiopulmonary Capacity in Healthy Individuals
The aim of our study is to compare the effects of face masks on cardiopulmonary capacity in young healthy individuals. The results of our study will show the effects of face masks commonly used during the pandemic period.
- Trial name
- NCT04785781
- Testing
- without masks, Surgical face mask (Vheal Med Co., Ltd., Istanbul, Turkey), FFP2\N95 protective face mask (Musk protective technology, Gaziantep, Turkey)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
COVID-19
A Study to Assess the Safety and Immunogenicity of the Coronavac Vaccine Against COVID-19
This is an open-label uncontrolled study in which all participants will receive two doses of the inactivated adsorbed vaccine against COVID-19, and will be followed up for safety and immunogenicity analysis for 24 months.
- Trial name
- NCT04756830
- Testing
- Adsorbed COVID-19 (inactivated) Vaccine
- Where
- 2 sites in Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
SARS-CoV Infection, Covid19
Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel
Emerging in China in December 2019, Covid-19, whose pathogen is SARS-Cov-2, was declared a global pandemic in March 2020. The clinical presentation is highly variable, ranging from asymptomatic forms to acute respiratory distress…
- Trial name
- SeroCovEms (NCT04516928)
- Testing
- Anti-SARS-CoV2 Serology, Questionnaire
- Where
- France
- Volunteers
- 392 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Pandemic, COVID-19, Sedentary Behavior
Socioeconomic Behavior Changes During the Pandemic
The goal of this observational study was to determine the changing shopping and movement habits of people during the period of March 2020- June 2021, when full and partial lockdown measures were in force due to the covid 19…
- Trial name
- NCT06473467
- Where
- Turkey (Türkiye)
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Istanbul University
NSCLC Stage IV, HIV
Nivolumab/Ipilimumab and Chemotherapy Combination in Advanced NSCLC Patients With HIV, HBV, HCV and Long Covid Syndrome
Study type: Phase 2 - Interventional Trial Number of patients to be enrolled: 105 Participating countries: Italy Study drugs: nivolumab and ipilimumab Cohort A: HBV and HCV patients Cohort B: HIV patients Cohort C: Long COVID…
- Conditions
- NSCLC Stage IV, HIV, HBV, HCV
- Trial name
- LUNGVIR (NCT05597800)
- Testing
- Nivolumab and Ipilimumab
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- Universita di Verona
Covid-19, Cancer
COVID-19 in Pediatric Oncology and Hematology Centers in France
Since the description of the first cases of infection in December 2019 in the Hubei province in China, a new coronavirus, called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), emerged and caused a pandemic.
- Trial name
- PEDONCOVID (NCT04433871)
- Testing
- No intervention, observational
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Vaccination Refusal, COVID-19 Pandemic
COVID-19 Messaging for Vaccination
This study will distribute videos of health professionals encouraging Covid-19 vaccination to a large sample of Facebook users, and will test the most effective ways to maximize diffusion of this vaccine-related content to…
- Trial name
- NCT05182554
- Testing
- Doctor Videos, Sharing Videos, Sharing Videos (Influencers)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
COVID-19
Feasibility and Safety of High-intensity Exercise Training in Patients Surviving COVID-19
This current protocol encompasses an investigator-blinded randomized exercise intervention in 10 COVID-19 survivors that have been discharged from hospital.
- Trial name
- NCT04549337
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COVID-19, Acute Respiratory Failure
Influence of Vibroacoustic Therapy Modes on the Course of Coronavirus Infection
Assessment of the dynamics of changes in physical, instrumental and laboratory parameters in patients with identified coronavirus infection complicated by acute respiratory failure included in the study in accordance with the…
- Conditions
- COVID-19, Acute Respiratory Failure, Vibration; Exposure
- Trial name
- NCT05143372
- Testing
- Vibrolung
- Where
- 3 sites in Kazakhstan
- Volunteers
- 60 people
- Sponsor
- Astana Medical University
Covid19
The Prevent Severe COVID-19 (PRESECO) Study
Double-blinded, placebo control, randomized, phase-3 clinical trial to evaluate clinical efficacy of Favipiravir in patients with mild to moderate symptoms related to COVID-19 infection
- Trial name
- PRESECO (NCT04600895)
- Testing
- Favipiravir
- Where
- 38 sites in United States, Brazil and 1 more
- Volunteers
- 1,187 people
- Sponsor
- Appili Therapeutics Inc.
Covid-19
Retrospective Study on Anosmias and Ageusias Linked to Infection by Covid-19
Odor and taste disturbances have increased dramatically during this time of the COVID-19 pandemic. Currently, we have very little information on the demographic and clinical characteristics of the affected population, on the…
- Trial name
- STras-Cov-2 (NCT04681157)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19
Study of Intravenous Administration of Allogeneic Adipose Stem Cells for COVID-19
This study is designed rapidly assess safety and preliminary efficacy in hospitalized patients with COVID-19 respiratory distress to provide clinical guidance for possible wider use in treating patients in this pandemic…
- Trial name
- CoronaStem1 (NCT04486001)
- Testing
- PSC-04
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sorrento Therapeutics, Inc.
Dyspnea Caused by 2019-nCoV
Bevacizumab in Post-acute Sequelae of COVID-19 : Efficacy and Safety (Pilot Study)
The aim of this research is to evaluate an innovative treatment, Bevacizumab, in patients suffering from respiratory complications related to COVID-19.
- Trial name
- BASECOVID (NCT07089719)
- Testing
- Bevacizumab Injection
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronavirus COVID-19, Respiratory Infection
EEG as Predictor of HD-tDCS Effectiveness in Long COVID-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Trial name
- NCT05289128
- Testing
- Experimental group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Paraíba
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