Clinical trials: Infectious Diseases Morbidity
Infertility, Female, Pelvic Inflammatory Disease
Effect of Prophylactic Antibiotics for Hysterosalpingography on Post Procedure Morbidity
The study will be a parallel randomised trial. There are two groups. The first group will be given prophylactic antibiotics before a procedure (hysterosalpingography) and the second group will be given a placebo(multivitamin).
- Trial name
- NCT04234945
- Testing
- Doxycycline Capsule, Multivitamins W/Iron Tab
- Where
- Nigeria
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
HIV Infections, Mental Disorders
Psychiatric Problems in Children and Adolescents Infected With HIV at Birth
The purpose of this study is to determine whether HIV and anti-HIV drugs cause mental health problems or make mental health problems worse in children and adolescents who were infected with HIV at birth.
- Trial name
- NCT00100542
- Testing
- Psychiatric interviews
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Prenatal Infection, Congenital Infection
Congenital CYtoMEgalovirus Infection in VIEtnam (CYMEVIE)
To estimate the prevalence of congenital CMV infection in Vietnamese neonates and relating morbidity within 2-year follow-up. Along with evaluating the predictive value of the presence and the level of CMV replication in the…
- Conditions
- Prenatal Infection, Congenital Infection, Neonatal Disease
- Trial name
- CYMEVIE (NCT04822142)
- Where
- Vietnam
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Hanoi Obstetrics and Gynecology Hospital
COVID-19, SARS-CoV 2 Infection, Health Disparities
EMPOWER - BAME vs COVID
The COVID-19 virus pandemic has massively affected us all. Moreover, there is a disproportionately high number of COVID-19 severe infections and deaths in British Black, Asian and minority ethnic (BAME) patients.
- Trial name
- NCT04399733
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Endometrial, Infection
EFFECTIVENESS OF PREOPERATIVE VAGINAL CLEANING IN REDUCING POST CAESAREAN INFECTIOUS MORBIDITY
After obtaining an informed consent a detailed history and clinical examination was performed. Labs were carried out to fulfill inclusion and exclusion criteria. Women were randomly divided into two groups.
- Conditions
- Endometrial, Infection, Surgical Site Infection Following Cesarean Delivery
- Trial name
- NCT07053995
- Testing
- Vaginal cleaning, Non vaginal cleansing
- Where
- Pakistan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
HIV, Infant Morbidity
Mitigating Infectious Morbidity and Growth Deficits in HIV Exposed Uninfected infanTs With Human Milk Oligosaccharides
Primary Objective: To evaluate the effects of synbiotics on infectious morbidity and growth while it is in place from 4 to 24 weeks of age.
- Conditions
- HIV, Infant Morbidity, Breast Feeding
- Trial name
- MIGH-T MO (NCT05282485)
- Testing
- Synbiotic, Maltodextrin
- Where
- South Africa
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Columbia University
Periodontitis, Gingivitis
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : improved dental health reduced risk of pneumonia better glucose…
- Conditions
- Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections
- Trial name
- NHOralHealth (NCT06890676)
- Testing
- Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Missouri Department of Health and Senior Services
Schistosomiasis, Malaria
The Effect of Praziquantel Treatment on Schistosoma Mansoni Morbidity and re-Infection Along Lake Victoria, Uganda
The overall objective of the project is to contribute to an increased knowledge about the effect of praziquantel on schistosomiasis related morbidity and re-infection level among communities living along Lake Victoria in Mayuge…
- Trial name
- NCT00215267
- Testing
- praziquantel
- Where
- Uganda
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- DBL -Institute for Health Research and Development
Childhood Mortality
Mortality Reduction After Oral Azithromycin: Morbidity Study
The long-term goal of this study is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood morbidity and increasing growth, and for the potential selection of antibiotic…
- Trial name
- MORDORMorb (NCT02048007)
- Testing
- Azithromycin
- Where
- 6 sites in United States, Malawi and 3 more
- Volunteers
- 72,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV/AIDS, Chronic Pain
Acceptance and Commitment Therapy for Aging People Living With HIV in Chronic Pain
Chronic pain impacts a large proportion of aging people living with HIV (aPLWH) and involves factors directly related to HIV (neurotoxicity) and psychosocial co-morbidities common in aPLWH (i.e. social isolation and loneliness).
- Trial name
- NCT03699020
- Testing
- Acceptance and Commitment Therapy (ACT), Chronic Pain Education
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Postpartum Infectious Morbidity in Cesarean Section Delivery
Role of Skin Cleansing and Prophylactic Antibiotic in Preventing Infectious Morbidity After Cesarean Section Delivery
This study aims to determine the effectiveness of skin cleansing and prophylactic antibiotics given to women undergoing a cesarean section for reducing the incidence of postpartum infectious morbidity and to assess potential…
- Trial name
- NCT03007706
- Testing
- Women undergo cesarean section delivery
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Raghda Gamal Mohamed
Postpartum Hemorrhage, Postpartum Depression
Postpartum Video Education in High Risk Populations
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Depression, Postpartum Sepsis, Postpartum Preeclampsia
- Trial name
- NCT06310720
- Testing
- Video Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
HIV, AIDS
The DC Cohort Longitudinal HIV Status Neutral Study
The goal of the DC Cohort is to establish a clinic-based city-wide longitudinal cohort that will describe clinical outcomes, and improve the quality of care for patients diagnosed with Human Immunodeficiency Virus/Acquired Immune…
- Trial name
- DC Cohort (NCT01206920)
- Where
- 14 sites in United States
- Volunteers
- 19,000 people, healthy volunteers welcome
- Sponsor
- George Washington University
Preterm Labor With Preterm Delivery, Premature Rupture of Membranes Prolonged
Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor
This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine…
- Trial name
- NCT05469984
- Testing
- Ampicillin Only Product, ampicillin plus gentamicin
- Where
- Israel
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
HIV Infections, Immune Activation
The University of Zimbabwe College of Health Science (UZ-CHS) BIRTH COHORT Study
Background Commencement of lifelong highly active antiretroviral therapy (HAART) immediately after HIV diagnosis (option B+), for treatment of human immunodeficiency virus (HIV), has greatly improved maternal-infant health in sub…
- Conditions
- HIV Infections, Immune Activation, Comorbidities
- Trial name
- UZ-CHS-BC (NCT04087239)
- Testing
- HIV
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
HIV Infection, Healthy
Trends of Morbidity and Mortality Among Thai HIV-infected and HIV-uninfected Patients: a Five-year Prospective Cohort Study
1. To describe the morbidity and clinical characteristics among HIV-infected patients and HIV-uninfected patients. 2. To identify the risk factors for the complication or morbidity among HIV-infected patients and HIV-uninfected…
- Trial name
- TNT-HIV (NCT01634477)
- Where
- Thailand
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Chronic Hepatitis b
Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B in the Rural Area of Niakhar, Senegal
This study aims at estimating the prevalence of chronic hepatitis B virus (HBV) infection in rural Senegal (area of Niakhar) and at evaluating the associated burden in terms of both health-related and socio-economic consequences.
- Trial name
- AMBASS (NCT03215732)
- Testing
- HBV testing with dried blood spots (DBS) technique
- Where
- Senegal
- Volunteers
- 3,119 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Prematurity, RSV
The Impact of a Short Intervention During RSV Prophylaxis on Influenza Vaccination Rate.
Premature infants (born before 34 wk) are routinely vaccinated against RSV but vaccination rate against influenza are low in spite of national programs.
- Conditions
- Prematurity, RSV, Influenza, Upper Respiratory Tract Infection
- Trial name
- NCT01985620
- Testing
- Educational intervention
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe