Clinical trials: Infectious Respiratory Diseases
Congestive Heart Failure, Angina Pectoris
Does Telephone Follow-up Improve Patients Satisfaction
Several studies have shown the importance of Telephone follow-up in reducing hospital readmissions for heart failure. Therefore, we aimed in this cohort to investigate whether telephone follow-up with patients discharged from the…
- Conditions
- Congestive Heart Failure, Angina Pectoris, Pneumonia, Urinary Tract Infection
- Trial name
- NCT00192738
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Rambam Health Care Campus
SARS-CoV Infection, Covid19
Cross Sectional CFAR HIV/COVID-19 Study
The main purpose of this research study is to learn the rate of SARS COV-2 on HIV infected children, adolescents, and youth receiving their primary HIV care at the University of Miami Miller School of Medicine.
- Trial name
- NCT04514016
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Miami
Covid19, Neurological Complication
COVID-19 Infection: Exploration of Respiratory Control Center Abnormalities
The purpose of the present study is to determine whether there is a decrease in the emotional response to experimental induction of dyspnea by hypoxic stimulation in subjects with a "neurological" form of COVID-19, compared to…
- Trial name
- CRC-COVID (NCT04363749)
- Testing
- hypoxia : 14.3 and 12.7% FIO2, hypercapnia 7% CO2, inspiratory mechanical constraint
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ventilator Associated Pneumonia, Respiratory Infection
Aerosolized Antibiotics and Respiratory Tract Infection in Patients on Mechanical Ventilation
The purpose of this study was to determine the effect of aerosolized antibiotics on respiratory infection in mechanically ventilated patients.We hypothesize that aerosolized antibiotics , which achieve high drug concentrations in…
- Conditions
- Ventilator Associated Pneumonia, Respiratory Infection, Tracheobronchitis
- Trial name
- NCT00396578
- Testing
- aerosolized vancomycin or gentamicin
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stony Brook University
Pulmonary Fungal Infection
An Efficacy and Safety Study of Itraconazole Sequential Therapy (Intravenous Injection Followed by Oral Solution) in Invasive Pulmonary Fungal Infections
The purpose of this study is to evaluate the efficacy and safety of itraconazole sequential therapy (intravenous injection/oral solution) in participants with invasive pulmonary fungal infections ([IPFI]; lung diseases caused by…
- Trial name
- NCT01823289
- Testing
- Itraconazole
- Volunteers
- 71 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Covid19, Kidney Diseases
Michigan Medicine COVID-19 Cohort: Clinical Characteristics, Inflammatory Markers and Outcomes of Patients Hospitalized for COVID-19
To better understand the role of inflammation in COVID-19, we established the Michigan Medicine COVID-19 Cohort (M2C2). M2C2 is a funded and ongoing cohort which has currently enrolled over 1500 adult patients (≥18 years) with…
- Conditions
- Covid19, Kidney Diseases, Inflammation, SARS-CoV Infection
- Trial name
- M2C2 (NCT04706533)
- Testing
- Biomarkers of inflammation
- Where
- United States
- Volunteers
- 3,402 people
- Sponsor
- University of Michigan
Laryngeal Cancer
Comparison of 2 Cefazolin Prophylactic Protocol in Laryngectomy Patients
Patients who need major head \& neck surgery are at risk of post operative wound infection. In spite of role of antibiotics in prophylaxis of clean contaminated head and neck surgery has been well documented, controversy exists…
- Trial name
- NCT00467948
- Testing
- cefazolin
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Tehran University of Medical Sciences
Covid19, Mechanical Ventilation Complication
Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation
The principal objective of the CONFIDENT trial is to assess the efficacy of two units (400-500 mL in total) of convalescent plasma, as compared to Standard of Care (SoC), to reduce day-28 mortality in patients with SARS-CoV-2…
- Conditions
- Covid19, Mechanical Ventilation Complication, Corona Virus Infection, Respiratory Failure
- Trial name
- CONFIDENT (NCT04558476)
- Testing
- Convalescent Plasma, Standard of Care
- Where
- 17 sites in Belgium
- Volunteers
- 475 people
- Sponsor
- University of Liege
Invasive Fungal Disease, Lung Transplant Recipients
Assessing Diagnostic Methods for Invasive Fungal Disease in Lung Transplant Recipients
This study aims to assess the diagnostic performance of different tests, including metagenomic next-generation sequencing (mNGS), real-time PCR, galactomannan assay, and lateral-flow device tests, in detecting invasive fungal…
- Conditions
- Invasive Fungal Disease, Lung Transplant Recipients, Invasive Pulmonary Aspergillosis, Pneumocystis Jirovecii Pneumonia
- Trial name
- NCT06654076
- Volunteers
- 109 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
COVID, Coronavirus
Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization
Our overarching goal is to improve the outcomes of critically ill COVID-19 patients with or at risk for development of acute kidney injury (AKI).
- Conditions
- COVID, Coronavirus, Coronavirus Infection, AKI
- Trial name
- NCT04530448
- Testing
- Sodium bicarbonate, Standard of Care
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- West Virginia University
Pneumococcal Vaccine
A Study to Evaluate Tolerability, Safety and Immunogenicity of MVX01 Pneumococcal Vaccine
The objectives of this first-in-human study is to evaluate the tolerability, safety, and immunogenicity of MVX01, a pneumococcal vaccine candidate, at four dose levels.
- Trial name
- NCT06337643
- Testing
- MVX01
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Matrivax Research and Development Corporation
COVID-19 Pneumonia, Sequelae of; Infection
Assessment of Long-term Sequelae of Coronavirus Disease 2019 (COVID-19) Pneumonia With Chest CT and Pulmonary Function Tests
The goal of this prospective multicentric study is to evaluate the presence of long-term pulmonary sequelae in patients who had required hospitalization for treating COVID-19 pneumonia, trough chest CT and pulmonary function…
- Conditions
- COVID-19 Pneumonia, Sequelae of; Infection, Respiratory Function Impaired, SARS CoV 2 Infection
- Trial name
- NCT05835128
- Where
- 2 sites in Portugal
- Volunteers
- 250 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Ventilator Associated Pneumonia
Toothbrushing and Ventilator-associated Pneumonia
The hypothesis is that adding the toothbrushing to the oral care with clorhexidine 0.12% could be reduce the incidence of ventilator-associated pneumonia due to that oral cavity may be an important reservoir of pathogens that…
- Trial name
- NCT01477099
- Testing
- Toothbrushing with a manual brush
- Where
- Spain
- Volunteers
- 436 people
- Sponsor
- Hospital Universitario de Canarias
Covid19, Vertical Transmission of Infectious Disease
Clinical Outcomes of Newborns Born to Pregnant Women With and Without COVID-19
A case-control trial was conducted to test the early postpartum period clinical outcomes of newborns born to pregnant women with and without COVID-19.
- Conditions
- Covid19, Vertical Transmission of Infectious Disease, Neonatal Infection, Pregnancy Related
- Trial name
- NCT04883801
- Testing
- Reviewed clinical records and laboratory results
- Where
- Turkey (Türkiye)
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
COVID
Double Therapy With IFN-beta 1b and Hydroxychloroquine
The novel coronavirus (SARS-CoV-2), is a single-stranded RNA coronavirus. The virus was first isolated from patients presented with pneumonia in Wuhan in December 2019.
- Trial name
- NCT04350281
- Testing
- Interferon Beta-1B, Hydroxychloroquine
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
SARS-CoV-2 Infection
Study to Evaluate the Efficacy and Safety of Oral RP7214, a DHODH Inhibitor, in Patients With Symptomatic Mild COVID-19 Infection.
This is a randomized, double-blind, placebo-controlled study of RP7214 in patients with symptomatic mild SARS-CoV-2 infection, having at least one high-risk feature (e.g., age > 60 years, hypertension, diabetes mellitus, chronic…
- Trial name
- NCT05007236
- Testing
- RP7214 + Standard of care (SOC)
- Where
- 16 sites in India
- Volunteers
- 163 people
- Sponsor
- Rhizen Pharmaceuticals SA
Coronavirus Covid-19 Infection Variant Omicron, SARS (Severe Acute Respiratory Syndrome)
Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.
The investigators will enroll 104 patients with severe COVID-19 infection that mechanical ventilation is needed for respiratory support.
- Trial name
- NOSARSCOVID (NCT04290871)
- Testing
- Nitric Oxide Gas, The delivery system will be set up anyway without study gas administration
- Sponsor
- Xijing Hospital
Respiratory Tract Infection Bacterial
Epidemiology of Hospital Acquired Pneumonia
This project aimed at analyzing and assessing of the early and late Hospital-Acquired Pneumonia(HAP) bacterial pathogens and their resistance to antimicrobial agents.
- Trial name
- HAP (NCT02614144)
- Volunteers
- 214 people
- Sponsor
- University Hospital Olomouc
Corona Virus Infection
Placebo Controlled Trial to Evaluate Zinc for the Treatment of COVID-19 in the Outpatient Setting
This is a randomized, double-blind, placebo-controlled trial to assess the efficacy of zinc in a higher risk COVID-19 positive outpatient population.
- Trial name
- NCT04621461
- Testing
- Zinc Sulfate 220 MG
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- St. Francis Hospital, New York
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.