Clinical trials: Infertility,Female
Infertility, Female, Infertility
Vitamin D and Polycystic Ovarian Syndrome (PCOS)
Primary Objectives: To evaluate the efficacy of metformin and Vitamin D supplementation on serum insulin and serum androgen levels (Total testosterone, Steroid Hormone Binding Globulin, Free Androgen Index) levels compared…
- Conditions
- Infertility, Female, Infertility, Vitamin D Deficiency
- Trial name
- NCT03989778
- Testing
- Vitamin D
- Where
- 2 sites in Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Polycystic Ovarian Syndrome, Infertility, Female
Spontaneous Reproductive Outcomes After Oral Inositol Supplementation in Infertile Polycystic Ovarian Syndrome Women.
Polycystic ovarian syndrome (PCOS) is a heterogeneous, multifaceted and complex disorder characterized by insulin resistance (IR), hyperinsulinemia, and hyperandrogenism leading ovarian disfunction and infertility.
- Trial name
- IROP-1 (NCT03598374)
- Testing
- Inositol + Folic acid, Folic acid, Regular intercourses
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Infertility, Female
Association Between Serum Thyroid-stimulating Hormone (TSH) and Intracytoplasmic Sperm Injection (ICSI) Outcome in Women Undergoing ICSI
TSH has been suggested to be involved in reproductive challenges such as ovulatory issues, infertility, miscarriage, and maternal complications for many years.
- Trial name
- NCT07449260
- Testing
- Basal TSH level
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Cairo University
Female Infertility
Looking for a Blood Epigenetic Signature to Predict Female Infertility
The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality.
- Trial name
- FIB_CARIPLO (NCT06098495)
- Testing
- search for epigenetic profile of infertility
- Where
- Italy
- Volunteers
- 1,456 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Infertility, Female
Single Dose Recombinant Human Follicle Stimulating Hormone Fc Husion Protein (KN015) in Healthy Volunteers
KN015,the active substance recombinant human Follicle Stimulating Hormone（FSH） Fc fusion protein, which belongs to the pharmaceutical class gonadotropins.KN015 is proposed for Assisted Reproductive Technology (ART) programs only.
- Trial name
- NCT03192527
- Testing
- KN015, Triptorelin
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alphamab Jilin Co., Ltd.
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Ovary; Anomaly, Infertility, Female
Autologous Platelet-Rich Plasma Intra-ovarian Infusion in Poor Responders
Autologous PRP intra ovarian infusion may improve ovarian response, patients' hormonal profile as well as fresh embryo transfer (ET)-ICSI cycles' outcome in patients presenting with Poor Ovarian Response (POR).
- Trial name
- PRP (NCT03937661)
- Testing
- PRP
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Infertility, Female, Reproductive Techniques, Assisted
Use of Autologous Exosomes vs Platelet Growth Factors to Regenerate the Ovary in Women With Infertility (Exosomas2024-1)
Ovarian stromal fibrosis resulting from each ovulation and due to aging is characterized by a decrease in hyaluronic acid concentrations, loss of synthesis and migration proteins CD63 and CD81, decreased miRNA125, miRNA21…
- Trial name
- Exosom2024-1 (NCT06773572)
- Testing
- Autologous Exososomes procedure obtained from the patients' own platelets., Patient group for activated platelet growth factors, the control group
- Where
- Venezuela
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biotech Fertility C.A.
Chorioamnionitis
Intrapartum Study of Sterile and Clean Gloves
The purpose of this study is to determine whether the use of sterile or clean gloves during labor exams affects the rate of chorioamnionitis. Chorioamnionitis is an infection of the membranes around the baby.
- Trial name
- NCT01852188
- Testing
- Type of glove used for intrapartum vaginal exams
- Where
- United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Female Infertility of Tubal Origin
Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief in HSG in a Tertiary Hospital in Kano
This study compares the effect of intracervical block with 1% lidocaine and intramuscular diclofenac 75mg in decreasing pain perception during hysterosalpingography.
- Trial name
- NCT02918812
- Testing
- Intracervical lidocaine, Intramuscular Diclofenac
- Where
- Nigeria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bayero University Kano, Nigeria
Infertility, Stress
Mandala Activity Accompanied With Two Different Music on Infertility
In this study; In this study, it is aimed to determine the stress level and the effect of the mandala activity, which is applied to two different musical accompaniments, on coping with stress in infertile women who have undergone…
- Conditions
- Infertility, Stress, Coping Behavior
- Trial name
- NCT05839171
- Testing
- music and mandala coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University
Infertility, Female
Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility
Prevalence of anti-H.pylori IgG in serum of women with unexplained infertility and comparing that with it's prevalence in fertile women.
- Trial name
- NCT02684604
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Opioid Use, Post-operative Pain
Opioid Use After Laparoscopic Salpingectomy
The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine if a multimodal, non-opioid pain control regimen is non-inferior to a…
- Conditions
- Opioid Use, Post-operative Pain, Sterility, Female
- Trial name
- NCT06434233
- Testing
- Acetaminophen, Ibuprofen, Oxycodone
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Fertility, Infertility
Internet-based Study of Fertility and Early Pregnancy (PEEPS)
The purpose of this study is to assess the feasibility of conducting an Internet-based prospective pregnancy study with preconception enrollment with women completing daily journals for up to 12 months while trying to conceive…
- Conditions
- Fertility, Infertility, Pregnancy, Abortion, Spontaneous
- Trial name
- PEEPS (NCT01904669)
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Courtney D.Lynch, PhD MPH
Infertility
Comapring Luteal Phase Support in IVF Patients Who Are at High Risk for Developing OHSS
The purpose of this study is to compare two luteal support protocols in In vitro fertilization patients (IVF) and are at risk of developing ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT02827656
- Testing
- Decapeptyl, hCG luteal support
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Tubal Obstruction
Antispasmodic Drug for Diagnosis Proximal Tubal Occlusion on Hysterosalpingography
This study finds premedication Hyoscine-N-butylbromide before hysterosalpingography have a potential effect for diagnosis of proximal tubal obstruction in infertile women.
- Trial name
- NCT02618785
- Testing
- hysterosalpingography
- Where
- Thailand
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Infertility, Female
Automated Intracytoplasmic Sperm Injection (ICSIA)
The purpose of this research study is to evaluate Overture's automated Intracytoplasmic Sperm Injection (ICSIA) System. ICSIA is an investigational medical device that automates injection of sperm into eggs.
- Trial name
- ICSIA (NCT05633316)
- Testing
- Investigational device named ICSIA, Manual ICSI
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Overture Life
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Female Infertility
Effectiveness of Low Dose Gonadotropin Stimulation Protocol Vs High Dose Gonadotropin Protocol in Poor Responders
In the present study we examined the effect of addition of CC to a low dose gonadotropin (150 IU/day) / GnRH antagonist protocol in comparison to a high gonadotropin dose (300 IU/day) regiment (short protocol) in women with poor…
- Trial name
- NCT06778733
- Testing
- Clomiphane citrate, recombinant human Follicle-Stimulating Hormone (r-FSH-alfa)
- Where
- 2 sites in Greece
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Athens
Infertility, Female
A New Revolutionary 3-Injection- Protocol in Infertile Women
This is a prospective randomised study of the evaluation of the clinical IVF results after following a new revolutionary 3-Injection- Protocol for controlled ovarian stimulation in infertile women.
- Trial name
- NCT03877185
- Testing
- Live birth rate
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assisting Nature