Clinical trials: Infertility,Female
Infertility, Infertility, Female
The Outcome of Two Protocols Used to Prepare Endometrium for Frozen Embryo Transfer
This is a RCT to test the outcome of two protocols used for preparation of the endometrium for frozen blastocyst embryo transfer
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- NCT04507022
- Testing
- Estradiol Valerate, Progesterone, Aromatase inhibitor
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rahem Fertility Center
Infertility, Assisted Reproductive Technology
Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes
This prospective observational cohort study investigates the role of the microbiome and metabolome in couples undergoing in vitro fertilization.
- Conditions
- Infertility, Assisted Reproductive Technology, Pregnancy Complications, Pregnancy Loss, Early
- Trial name
- Mi IVF (NCT07532629)
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Endometriosis, Pelvic Pain
Machine Learning for Early Diagnosis of Endometriosis(MLEndo)
The project aims to create a large prospective data bank using the Lucy medical mobile application and collect and analyze patient profiles and structured clinical data with artificial intelligence.
- Conditions
- Endometriosis, Pelvic Pain, Infertility, Female
- Trial name
- MLEndo (NCT06147687)
- Testing
- Self reported data collection
- Where
- 2 sites in Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Normal Endometrial Physiology
Endometrial Basis for Infertility in Women With Recurrent Implantation Failure and Pregnancy Loss
Background: Pregnancy loss is the most common complication of pregnancy. It occurs in roughly one-half of natural conceptions. It most frequently occurs in the first 2 to 3 weeks of pregnancy.
- Trial name
- NCT04939064
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Periodontitis, Gingivitis
Evaluation of Matrix Metalloproteinase 8 Salivary Test for Diagnosis of Periodontitis
Despite the great progress in understanding the causes of infertility, the reason for the failure of pregnancy has not been discovered among 25% of infertile couples.
- Conditions
- Periodontitis, Gingivitis, Infertility
- Trial name
- NCT03542630
- Testing
- salivary MMP8 test, periodontal examination, blood tests
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Polycystic Ovary Syndrome
Treatment of Hyperandrogenism Versus Insulin Resistance in Infertile Polycystic Ovary Syndrome (PCOS) Women
The goal of this three-armed randomized controlled trial is to establish the relative roles of treatment of hyperandrogenism versus obesity (as the largest modifiable factor contributing to insulin resistance) in treating…
- Trial name
- OWL-PCOS (NCT00704912)
- Testing
- Orlistat/Meal Replacement/Lifestyle Modification, Loestrin 1/20, Combination of treatments
- Where
- 2 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Childbearing, Delayed, Marriage Age
Youth Outlook on Life Opportunities Study
Singapore's fertility rate is currently below 1.2, raising concerns about population ageing and long-term sustainability. The fertility decline is characterized by falling birth rates among women in their 20s with almost no…
- Conditions
- Childbearing, Delayed, Marriage Age, Educational Problems, Anxiety
- Trial name
- NCT05026619
- Testing
- Information about age-related fertility, Information about policy initiatives, Information about diabetes
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Infertility, Female
Can Virtual Reality Technology Improve the Patient Experience in Oocyte Retrieval?
A non-pharmacological, non-blinded, randomized cohort study that will investigate the effect of Virtual Reality technology on the patient experience during oocyte retrieval.
- Trial name
- NCT05826938
- Testing
- Virtual reality technology
- Where
- Denmark
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility, Female Infertility
What is the Optimal Cycle Regimen for Frozen- Thawed Embryo Transfer Cycles
Investigators will be comparing artificial (HRT) frozen-thawed embryo transfer cycles to correctly conducted spontaneous natural cycles after the transfer of a chromosomally normal embryo.
- Conditions
- Infertility, Female Infertility, Pregnancy Early
- Trial name
- NCT03954587
- Where
- United Arab Emirates
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, Female
Melatonin Study Between Diminished and Normal Responder in IVF
Poor sleep quality may lead to increase in oxidative stress and free radicals which in turn may decrease the reproductive function.
- Trial name
- NCT03117725
- Testing
- Melatonin adminstration
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Infertility, Vaginal Blood Loss
A Virtual Reality System for Pain and Anxiety Management During Outpatient Hysteroscopy
To evaluate the effectiveness of VR as a distraction technique in the management of acute pain and anxiety during operative hysteroscopy in the outpatient setting.
- Trial name
- NCT04625920
- Testing
- SootheVR: AppliedVR, Los Angeles, California
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Infertility, Female, Infertility Unexplained
Pro-inflammatory Cytokines and Implantation Process in Women With Primary Idiopathic Infertility
Infertility is a common, worldwide problem. In about 20% of couples, the causative agent of infertility cannot be identified after routine diagnostic tests.
- Conditions
- Infertility, Female, Infertility Unexplained, Inflammatory Response
- Trial name
- NCT05190250
- Testing
- Pipelle biopsy
- Where
- Poland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Infertility, Intrauterine Insemination (IUI)
The Level of Infertility Distress and Fertility Readiness of Women
The infertility treatment process is a multidisciplinary teamwork involving different professional groups. Especially the Controlled Ovarian Hyperstimulation (COH) protocols applied during the infertility treatment process…
- Trial name
- NCT06659497
- Testing
- web-based patient education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duzce University
Infertility (IVF Patients), Infertile Females or Females with Ovarian Insufficiency
Evaluation of Pregnancy Outcome with Usage of Drug-free In-vitro Activation of Follicles Ovary
This study is the pilot study to evaluate the effect of Drug-free in vitro activation to improve the outcomes of IVF in poor responder women
- Trial name
- NCT06769789
- Testing
- Drug free invitro activation Ovary
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Malihe Mahmoudinia
Female Infertility
Looking for a Blood Epigenetic Signature to Predict Female Infertility
The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality.
- Trial name
- FIB_CARIPLO (NCT06098495)
- Testing
- search for epigenetic profile of infertility
- Where
- Italy
- Volunteers
- 1,456 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Association Model; Chinese Medicine Physique Types; Health Care Base on Traditional Chinese Medicine; Women Infertility
Discussion on the Association Model of Traditional Chinese Medi-cine Body Constitution and Female Infertility
Abstract Background: Infertility may cause physiological and psychological distress. The Health Promotion Administration in Taiwan has listed infertility improvement under the "Reproductive health and prevention section" in the…
- Trial name
- NCT05725629
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Infertility, Female
CAPA In-vitro Oocyte Maturation (CUHK Medical Centre Limited)
In vitro oocyte maturation (IVM) is a mild-approach assisted reproductive technology (ART). Because of its simplicity, the more favorable financial implications (reduced cost) for patients, and the lower health risk profile of…
- Trial name
- NCT07083427
- Testing
- CAPA-IVM
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Infertility, Female
CAPA In-vitro Oocyte Maturation
In vitro oocyte maturation (IVM) is a mild-approach assisted reproductive technology (ART). Because of its simplicity, the more favorable financial implications (reduced cost) for patients, and the lower health risk profile of…
- Trial name
- NCT06984081
- Testing
- CAPA IVM
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endometrioma, Infertility
Ethanol Sclerotherapy Prior to ART
The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are: 1.
- Conditions
- Endometrioma, Infertility, Sclerotherapy, ART
- Trial name
- START (NCT05962775)
- Testing
- Ethanol Sclerotherapy for Endometrioma
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara University