Clinical trials: Infertility,Male
Infertility
Quantitative MRI for Functional Imaging of the Testis: A New Methodology for Evaluation of the Infertile Male
Infertility-the inability to conceive despite one year of properly timed unprotected intercourse-is a common problem. Of all types of male factor infertility, non-obstructive azoospermia may be the most difficult for couples.
- Trial name
- NCT02756325
- Testing
- MRI
- Sponsor
- NYU Langone Health
Male Infertility, Nonobstructive Azoospermia
Platelet Rich Plasma Testis Treatment for Infertile Men
Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who already underwent a negative sperm retrieval.
- Conditions
- Male Infertility, Nonobstructive Azoospermia, Azoospermia
- Trial name
- NCT05479474
- Testing
- Platelet rich plasma
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Psychological Experience in Fertility Treatment, Hypogonadism
Male Experiences With Intra Cytoplasmic Sperm Injection (ICSI) and Reduced Sperm Quality
Several international studies indicate that men with reduced semen quality often feel overlooked in the context of fertility treatment.
- Conditions
- Psychological Experience in Fertility Treatment, Hypogonadism, Testosteron Levels, Quality of Life
- Trial name
- NCT07546435
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility, Infertility, Male
Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection
Laser-assisted intracytoplasmic sperm injection (ICSI) has been suggested as a more effective alterative to conventional ICSI when this method of insemination is indicated for patients undergoing in vitro fertilization (IVF).
- Trial name
- NCT00114725
- Testing
- Laser-assisted intracytoplasmic sperm injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Male Infertility, Heart Valve Disease
Warfarin Effects on Male Fertility After Cardiac Surgery
Young male patients undergoing cardiac surgery may require oral anticoagulation with warfarin either lifelong, such as after mechanical valve replacement, or for a limited postoperative period, for example following valve repair…
- Trial name
- NCT07330869
- Testing
- Semen analysis, sperm DNA fragmentation and hormonal evaluation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Città di Lecce Hospital, GVM Care & Research
Infertility, Sexuality
Sexual Counseling According to the PLISSIT Model in Primary Infertile Couples
This study was planned to determine the effect of sexual counseling given to primary infertile couples in line with the PLISSIT model on sexual function and sexual satisfaction.
- Conditions
- Infertility, Sexuality, Sexual Dysfunction, Nurse's Role
- Trial name
- NCT04791683
- Testing
- sexaul counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Non-obstructive Azoospermia
Use of Semen TEX101 to Improve Sperm Retrieval Rates for Men With Non-obstructive Azoospermia
The investigators hypothesize that sperm production varies with time in men with no sperm in semen (non-obstructive azoospermia, NOA) and that the semen protein, TEX101, is able to monitor these changes.
- Trial name
- NCT02851966
- Testing
- mTESE
- Where
- 3 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Mount Sinai Hospital, Canada
Male Infertility
A Study of the Pre- and Post-operative Semen Analyses and Reproductive Hormone Levels of Men Undergoing Weight-reduction Surgery
A correlation between obesity and male fertility has been observed in a few clinical studies. Normal weight men appear to have higher sperm concentrations and sperm motility when compared to obese men, suggesting that weight loss…
- Trial name
- NCT00596739
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Infertility, Male, Cancer
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy.
- Conditions
- Infertility, Male, Cancer, Autoimmune Disorder
- Trial name
- NCT04452305
- Testing
- Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pittsburgh
Male Infertility, Oxidative Stress
Effect of Daily Intake of Gazpacho on Semen Quality and Oxidative Stress
The goal of this clinical trial is to learn whether drinking a daily serving of gazpacho can improve semen quality in men with reduced sperm quality.
- Conditions
- Male Infertility, Oxidative Stress, Subfertility, Oligozoospermia
- Trial name
- G-OXSEM (NCT07375238)
- Testing
- Standardized Mediterranean Diet, Gazpacho
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Ginefiv
Spermatozoa, Abnormal, in Vitro Fertilization
The Influence of Sperm Morphology and Functional Indices on Blastocyst Development in Assisted Reproduction
Samples from male partners of 120 infertile couples undergoing IVF were analyzed. Sperm morphology was assessed using the SpermBlue staining method, while TZI, MAI, and SDI were calculated.
- Conditions
- Spermatozoa, Abnormal, in Vitro Fertilization, Blastocyst, Aneuploidy
- Trial name
- NCT06801652
- Testing
- Sperm morphology indexes
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Calla IVF Center
Conventional IVF, ICSI
Child Follow-up in Women Treated With Conventional IVF or ICSI
To compare the physical, mental and motor development of babies born from pregnancy using ICSI technique and and conventional IVF in non-male factor infertile couples.
- Trial name
- NCT04866524
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 322 people
- Sponsor
- Mỹ Đức Hospital
Endocrine Disease, Infertility
Hormonal Regulation of Puberty and Fertility
Background: The body produces gonadotropin-releasing hormone (GnRH) about every 2 hours. GnRH travels through the bloodstream to the pituitary gland, where it stimulates the gland to produce hormones called gonadotropins.
- Conditions
- Endocrine Disease, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01511588
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Healthy, Male Infertility
Expanding Fertility Care to Poor and Low Resourced Settings Study
The investigators currently lack an understanding of barriers to completing the male factor infertility evaluation. Furthermore, as the investigators continue to expand access to fertility treatment particularly within…
- Conditions
- Healthy, Male Infertility, Infertility, Male, Fertility Disorders
- Trial name
- EXPLORE (NCT05205733)
- Testing
- Mail-in semen analysis kit
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients
Ovulatory dysfunction affects 18 to 25% of infertile women, the most common identifiable condition is polycystic ovarian syndrome (PCOS).
- Trial name
- HIP (NCT05555680)
- Testing
- Ferriman-Gallwey Score
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Clinique Ovo
Non-obstructive Azoospermia, Hormone Deficiency
Sperm Retrieval Rates in Non-obstructive Azoospermic Men Subjected to Gonadotropin Therapy
Azoospermia is defined as the complete absence of spermatozoa in the ejaculate. Two-thirds of azoospermic patients have non-obstructive azoospermia (NOA); the latter comprises up to 10% of infertile men overall.
- Conditions
- Non-obstructive Azoospermia, Hormone Deficiency, Hypogonadism, Male, Male Infertility
- Trial name
- NCT05110391
- Testing
- Hormonal Therapy Agent
- Where
- Brazil
- Volunteers
- 616 people
- Sponsor
- ANDROFERT - Clinica de Andrologia e Reproducao Humana
Covid19, Infertility, Male
Impact of the Coronavirus Disease 2019 (COVID-19) on Sperm Parameters
This study aims to better understand the effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, virus that causes the coronavirus disease 2019 (COVID-19), on male fertility.
- Trial name
- NCT04937608
- Testing
- Sperm analysis
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Fertilys
Infertility, Male
The Effect of a Multimodal Lifestyle Program on Male Fertility
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment.
- Trial name
- NCT04761250
- Testing
- Lifestyle
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
PCOS, Endometriosis
Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment
tTe investigators estimate pomegranate supplementation effect on oxidative stress in infertile women with PCOS, endometriosis and advanced maternal age during IVF treatment.
- Conditions
- PCOS, Endometriosis, Advised Maternal Age, Male Factor Infertility
- Trial name
- NCT03978013
- Testing
- Pomegranate juice, Apple juice
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Prostate Cancer, Sexual Dysfunction and Infertility
Hormone Therapy in Treating Patients With Prostate Cancer
RATIONALE: Male hormones can stimulate the growth of prostate cancer cells. Hormone therapy using flutamide and finasteride may fight prostate cancer by reducing the production of male hormones.
- Trial name
- NCT00003323
- Testing
- finasteride, flutamide, quality-of-life assessment
- Where
- 43 sites in United States
- Volunteers
- 101 people
- Sponsor
- Alliance for Clinical Trials in Oncology