Clinical trials: Infertility/Sterility
Hiv, Contraception
Mobile Phone Messaging to Improve Reproductive Health for Women Living With HIV in Kenya (Mobile WACh Empower)
Use of a mobile health (mHealth) intervention to provide reproductive life counseling to women living with HIV may improve delivery of integrated reproductive health/HIV services and prevent adverse reproductive health outcomes.
- Conditions
- Hiv, Contraception, Fertility Issues
- Trial name
- NCT05285670
- Testing
- Digital counseling plus interactive two-way SMS dialogue
- Where
- 10 sites in Kenya
- Volunteers
- 3,310 people, healthy volunteers welcome
- Sponsor
- University of Washington
Male Infertility, HCV
Effect of New Oral Treatment for Hepatitis C Virus on Seminal Parameters
Hepatitis C virus is commona viral infection. Direct-acting antiviral (DAA) oral drugs has been used in treatment of HCVs. the effect of these drugs on male infertility is still under investigation.
- Trial name
- NCT05616598
- Testing
- Sofosbuvir +daclatasvir+ simeprevir+Ribavirin
- Where
- 2 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Benha University
Fertility Issues
Continuous Double Ovarian Stimulation.
To evaluate the efficacy of the weekly use of corifollitropin alfa in double ovarian stimulation process and to compare it to the conventional protocol with daily medication administration.
- Trial name
- NCT05815719
- Testing
- Corifollitropin Alfa, Follitropin Alfa, Follitropin Alfa Biosimilar
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility
The Effect of Follicular Flushing on Oocyte Retrieval Rate and Embryo Quality
Researchers will investigate the effect of flushing according to follicle size on the success of obtaining oocytes from a single follicle.
- Trial name
- NCT05584436
- Where
- Turkey (Türkiye)
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infertility
Metformin Use and Clinical Pregnancy Rate in Women With Unexplained Infertility
The aim of this study is to asses the effect of metformin on clinical pregnancy rate in women with unexplained infertility (randomized controlled trial).
- Trial name
- NCT03681197
- Testing
- Metformin, Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Elham Raafat
Infertility
Overture Metabolomics Non-Selection Study
In this study, study investigators will collect embryo culture media on day 5 of vitro fertilization (IVF) culture, prior to vitrification and embryo transfer for testing via Metabolomic screening.
- Trial name
- NCT04878991
- Testing
- Overture Metabolomics Embryo Selection
- Where
- 2 sites in United States, Spain
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Overture Life
Infertility, Female
The Effect of Motivational Interviews
The aim of the study was to determine the effect of motivational interviews applied to infertile women on their ability to cope with infertility, self-efficacy and stress.
- Trial name
- NCT06181890
- Testing
- Motivational Interview
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Infertility, Female, Infertility of Uterine Origin
Progesterone Levels and Endometrial Compaction in Frozen-Thawed Embryo Transfer Cycles
This study is intended to determine whether there is a correlation between endometrial compaction and serum progesterone levels on the day of frozen embryo transfers by using transvaginal sonography for the endometrial assessment.
- Conditions
- Infertility, Female, Infertility of Uterine Origin, Implantation; Placenta
- Trial name
- NCT04554654
- Testing
- transvaginal ultrasound,
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cem Demirel
Infertility, Infertility, Female
The Outcome of Two Protocols Used to Prepare Endometrium for Frozen Embryo Transfer
This is a RCT to test the outcome of two protocols used for preparation of the endometrium for frozen blastocyst embryo transfer
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- NCT04507022
- Testing
- Estradiol Valerate, Progesterone, Aromatase inhibitor
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rahem Fertility Center
Female Infertility, Uterine Fibroid
The Effects of Uterine Fibroids on Pregnancy in Women
Female fertility may be affected by uterine fibroids, although this association has not been elucidated. This retrospective cohort study aims to evaluate the impact of fibroids on women fertility.
- Trial name
- NCT06020924
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,658 people, healthy volunteers welcome
- Sponsor
- Wenwen Wang
Infertility
Optimal Timing of Intrauterine Insemination (IUI) When Utilizing Superovulation Combined With GnRH Antagonists
The timing of IUI following ovulation induction has been the subject of many studies and a consensus has developed that a single insemination approximately thirty-six hours after ovulation induction is sufficien.
- Trial name
- NCT00675142
- Testing
- Intrauterine Insemination
- Where
- Israel
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Subfertility
Predicting Ovarian Response in Artificial Insemination With Low Stimulation
This large prospective multi-center cohort study aims to identify patient's characteristics that significantly influence ovarian response to mild stimulation with a fixed dose of 75 IU recombinant FSH.
- Trial name
- NCT01662180
- Testing
- Follicle Stimulating Hormone
- Where
- 7 sites in Netherlands
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Isala
T-Shaped Uterus, Infertility, Female
Investigation of U1-A Uterine Anomalies Implantation Markers From the Lateral Walls of the Endometrium
Various types and classes of uterine malformations have been identified and the ESHRE / ESGE classification system has recently been published on female genital system anomalies.
- Conditions
- T-Shaped Uterus, Infertility, Female, Genital Tract Anomalies
- Trial name
- NCT04501003
- Testing
- Bipolar cutting electrode (26040 BL1 Karl Storz, Tuttlingen)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Infertile Patient Undergoing ICSI Procedure
Advanced Sperm Selection in ICSI: A Comparative Study of PICSI and ZyMot
our study explores the effectiveness of two advanced sperm selection techniques-PICSI and the ZyMot microfluidic device-in improving outcomes of Intracytoplasmic Sperm Injection (ICSI).
- Trial name
- NCT07240779
- Testing
- picsi dish
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sunrise Fertility Center
Infertility
Cost Effectiveness Analysis for Induction of Ovulation in the Polycystic Ovary Syndrome by Letrozole Versus Clomiphene Citrate
To evaluate cost effectiveness of Letrozole versus clomiphene citrate (CC) in induction of ovulation in patients with polycystic ovary syndrome.
- Trial name
- NCT04361175
- Testing
- Letrozole, Clomiphine Citrate
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility, Female
Intracervical Anasthesia in Outpatient Hystroscopy, Can Procedure be Completed Diagnostic and Therapeutic With no Need to General Anaesthesia
Single blind randomized controlled study in which 80 patients coming for hystroscopy due to multiple indication as infertility, AUB and missed IUD were assigned for our study.
- Trial name
- NCT03747692
- Testing
- study group, control group
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility
Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles
This is a randomized, double-blind, single center clinical trial study to compare oocyte competence and risk of ovarian hyperstimulation syndrome (OHSS) after receiving the standard dose of human chorionic gonadotropin (hCG)…
- Trial name
- NCT02310919
- Testing
- Low dose hCG plus FSH co-trigger, Standard dose of hCG
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility
Frozen Embryo Transfer (FET) in Natural Cycles or in Natural Cycles Controlled by Human Chorionic Gonadotropin (hCG) Administration
The rational of the study is to assess the implantation, pregnancy and live birth rates after the transfer of frozen- thawed embryos in natural cycles with spontaneous Luteinizing Hormone (LH)/Progesterone rise or in natural…
- Trial name
- FRET (NCT00809107)
- Testing
- HCG
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Periodontal Disease, Gingivitis and Periodontal Diseases
Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease
Periodontal disease is a chronic inflammatory condition of the tooth-supporting tissues in which the host inflammatory response drives the destruction of alveolar bone and periodontal attachment.
- Conditions
- Periodontal Disease, Gingivitis and Periodontal Diseases, Biomarker Discovery and Validation, Pathways
- Trial name
- BYHN-GCF-HIPPO (NCT07759466)
- Testing
- ELISA Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Inonu University
Infertility, IVF
Health of IVF Versus IVM Children (FM-BABIES)
The investigators conduct a follow up of our randomized controlled trial (RCT) to investigate the development of children born from In-vitro fertilization (IVF) and In-vitro maturation (IVM), in order to give strong evidence…
- Conditions
- Infertility, IVF, IVM
- Trial name
- FM-BABIES (NCT04296357)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
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